Press release
Chemotherapy-Induced Nausea and Vomiting (CINV) Market to Reach USD 4.02 Billion by 2034
Chemotherapy-Induced Nausea and Vomiting
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Growing global cancer prevalence, increasing adoption of highly emetogenic chemotherapy regimens, and the development of next-generation serotonin (5-HT3), neurokinin-1 (NK1) receptor antagonists based therapies are key factors driving market growth.
In 2024, the global CINV market is valued at USD 2.54 billion and is projected to reach USD 4.02 billion by 2034, growing at a CAGR of 4.7%.
Market Overview
• Market Size 2024: USD 2.54 billion
• Forecast 2034: USD 4.02 billion
• CAGR (2025-2034): 4.7%
Key Drivers
• Rising global incidence of cancer and chemotherapy usage.
• Strong demand for combination therapies improving efficacy.
• Increasing use of NK1 receptor antagonists and serotonin receptor antagonists.
• Advances in supportive oncology care and patient quality of life focus.
• Expansion of oncology drug pipelines in emerging markets.
Key Challenges
• High cost of branded anti-emetics.
• Limited access in low- and middle-income countries.
• Generic erosion of established therapies.
• Patient variability in treatment response.
Leading Players
Helsinn Healthcare, Merck & Co., GlaxoSmithKline, Roche Holding AG, Heron Therapeutics, Eisai Co. Ltd., Tesaro (GSK), Kyowa Kirin, and Dr. Reddy's Laboratories.
Segmentation Analysis
By Drug Class
• Serotonin (5-HT3) Receptor Antagonists
• Neurokinin-1 (NK1) Receptor Antagonists
• Dopamine Antagonists
• Corticosteroids
• Combination Therapies
By Distribution Channel
• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies
By End User
• Cancer Treatment Centers
• Hospitals
• Specialty Clinics
• Homecare
Summary:
Combination therapies dominate due to their ability to manage acute and delayed CINV more effectively. NK1 receptor antagonists are also gaining traction, particularly in high-emetogenic chemotherapy regimens.
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Regional Analysis
• North America
The largest market, driven by advanced oncology infrastructure, high cancer prevalence, and strong adoption of innovative therapies.
• Europe
Significant demand for anti-emetics, supported by government healthcare programs and increasing oncology care spending.
• Asia-Pacific
Fastest-growing market due to rising cancer incidence, expanding healthcare access in China and India, and government focus on oncology care.
• Middle East & Africa
Moderate growth, with demand driven by cancer treatment centers in GCC countries and South Africa.
• Latin America
Brazil and Mexico lead adoption due to expanding oncology treatment facilities and improved patient access to supportive therapies.
Summary:
North America and Europe dominate due to advanced oncology infrastructure, while Asia-Pacific is expected to see the fastest growth with expanding access to cancer care and drug availability.
Market Dynamics
Growth Drivers
1. Increasing global cancer burden requiring supportive oncology therapies.
2. Development of next-generation NK1 and 5-HT3 receptor antagonists.
3. Growth in combination therapies for better treatment outcomes.
4. Increasing healthcare expenditure in emerging economies.
5. Rising emphasis on patient-centric cancer care.
Challenges
• High cost and limited reimbursement in some regions.
• Patent expirations and generic competition.
• Unequal access to advanced therapies in low-resource settings.
• Side effects and patient compliance issues.
Latest Trends
• Development of oral fixed-dose combination drugs for convenience.
• Use of therapies for refractory CINV.
• Clinical trials focusing on precision oncology supportive care.
• Increasing role of biosimilars in reducing therapy costs.
• Partnerships between pharma companies and oncology centers for patient support programs.
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Competitor Analysis
Key Players
• Helsinn Healthcare
• Merck & Co.
• GlaxoSmithKline
• Roche Holding AG
• Heron Therapeutics
• Eisai Co. Ltd.
• Tesaro (GSK)
• Kyowa Kirin
• Dr. Reddy's Laboratories
Competitive Landscape
The CINV market is moderately consolidated, with Helsinn and Merck leading in NK1 receptor antagonists, while Roche and GSK focus on combination therapies. Generic drugmakers are increasing their market share by offering cost-effective alternatives, especially in Asia-Pacific and Latin America.
Conclusion
The CINV market plays a critical role in improving cancer treatment adherence and patient quality of life. Valued at USD 2.54 billion in 2024, the market is projected to reach USD 4.02 billion by 2034, growing at a CAGR of 4.7%.
Future opportunities lie in oral combination therapies and biosimilars. Companies that focus on innovation, affordability, and patient accessibility will remain leaders in this essential supportive oncology segment.
This report is also available in the following languages : Japanese (化学療法誘発性の吐き気と嘔吐), Korean (화학 요법으로 인한 메스꺼움 및 구토), Chinese (化疗引起的恶心和呕吐), French (Nausées et vomissements induits par la chimiothérapie), German (Durch Chemotherapie verursachte Übelkeit und Erbrechen), and Italian (Nausea e vomito indotti dalla chemioterapia), etc.
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