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Bevacizumab Biosimilars Market Forecasted to Reach USD 9.8 Billion by 2034, Key Players: Amgen & Pfizer

09-30-2025 02:33 PM CET | Health & Medicine

Press release from: Exactitude Consultancy

Bevacizumab Biosimilars

Bevacizumab Biosimilars

Biosimilars are reshaping the pharmaceutical industry by offering cost-effective alternatives to biologic therapies. Among these, Bevacizumab biosimilars have become a critical focus due to their role in treating cancers such as colorectal, lung, ovarian, and glioblastomas. Bevacizumab, originally commercialized under the brand Avastin by Genentech/Roche, is a monoclonal antibody that inhibits vascular endothelial growth factor (VEGF), thereby restricting tumor angiogenesis. With the original patent expiries, multiple biosimilars have entered the market, driving affordability and accessibility. Rising global cancer prevalence, escalating healthcare costs, and strong regulatory support for biosimilars are fueling demand.

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Market Overview
• Market Size 2024: USD 2.7 billion
• Forecast 2034: USD 9.8 billion
• CAGR (2024-2034): 13.5%

Key Highlights:
• Patent expiries of Avastin have opened lucrative opportunities for biosimilar manufacturers.
• Increasing cancer incidence worldwide, particularly colorectal and lung cancers, drives demand.
• Governments and payers are encouraging biosimilar adoption to reduce treatment costs.
• Strategic partnerships between biotech firms and pharmaceutical companies are expediting commercialization.

Challenges include regulatory complexities, physician reluctance in some regions, and high development costs. Yet, the overall trajectory remains strongly positive.

Market Segmentation
By Product Type
• Recombinant Humanized Monoclonal Antibodies (Bevacizumab)
• Combination Formulations

By Indication
• Colorectal Cancer
• Non-small Cell Lung Cancer (NSCLC)
• Renal Cell Carcinoma
• Ovarian Cancer
• Glioblastoma
• Others (including cervical and hepatocellular cancers)

By End User
• Hospitals
• Specialty Clinics
• Research & Academic Institutes
• Others

By Distribution Channel
• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies

Segmentation Summary:
Colorectal cancer remains the leading application segment due to its high global prevalence. NSCLC is the fastest-growing segment, reflecting the increasing burden of lung cancer worldwide. Hospitals dominate as the primary end users, while online pharmacies are expected to grow rapidly with rising digital healthcare adoption.

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Regional Analysis
North America
• Largest market in 2024, driven by strong biosimilar uptake and favorable reimbursement policies.
• The U.S. leads, with increasing FDA approvals and strong presence of both originator and biosimilar manufacturers.
Europe
• Accounts for nearly 30% of the market.
• EMA's supportive regulatory framework and cost-containment policies are accelerating biosimilar adoption.
• Germany, France, and the UK are leading markets.
Asia-Pacific
• Fastest-growing region, projected CAGR of over 15%.
• India, China, and South Korea are key hubs due to growing cancer burden and biosimilar manufacturing capacity.
• Increasing healthcare expenditure and government initiatives boost adoption.
Middle East & Africa
• Early-stage adoption, but demand is rising as oncology treatment access expands.
• Partnerships with global pharma companies support availability.
Latin America
• Brazil and Mexico are primary contributors, supported by expanding oncology care infrastructure.
• Cost advantages of biosimilars over branded biologics drive growth.
Regional Summary:
North America and Europe dominate current adoption, but Asia-Pacific will emerge as the fastest-growing market by 2034, fueled by local manufacturing capabilities, government support, and high unmet medical needs.

Market Dynamics
Growth Drivers
• Patent Expiry of Avastin: Creates significant opportunities for biosimilar entrants.
• Rising Cancer Incidence: Global burden of colorectal, lung, and ovarian cancers fuels demand.
• Cost-effectiveness: Biosimilars offer affordable alternatives, increasing patient accessibility.
• Regulatory Support: Streamlined approval pathways in Europe, U.S., and Asia are encouraging innovation.

Key Challenges
• Physician Reluctance: Some healthcare professionals remain cautious in prescribing biosimilars.
• High Development Costs: Manufacturing biologics and meeting regulatory requirements is capital intensive.
• Market Competition: Intense competition among biosimilar developers can limit pricing power.

Latest Trends
• Combination Therapies: Biosimilars being tested with other oncology treatments to enhance outcomes.
• Strategic Partnerships: Co-development and licensing deals are becoming common to reduce risks.
• Oncology Pipeline Expansion: Focus shifting toward biosimilars for other monoclonal antibodies in oncology.
• Digital Health Integration: E-commerce and online pharmacies enabling wider access to biosimilars.

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Competitive Landscape
Key Players
• Amgen Inc.
• Pfizer Inc.
• Biocon Biologics Ltd.
• Celltrion Healthcare
• Samsung Bioepis
• Teva Pharmaceutical Industries Ltd.
• Mylan N.V. (Viatris)
• Genentech (Roche)
• Dr. Reddy's Laboratories
• Sandoz (Novartis Division)
• BeiGene
• Innovent Biologics
• STADA Arzneimittel AG
• Apotex Inc.
• Amneal Pharmaceuticals

Competitive Summary:
The Bevacizumab biosimilars market is highly competitive, with several global and regional players vying for market share. Partnerships and co-marketing agreements are common strategies to accelerate commercialization. Companies like Amgen, Pfizer, and Biocon have already launched biosimilars in multiple markets, while Asian firms like Celltrion and Samsung Bioepis are expanding aggressively. Roche continues to defend its Avastin franchise but faces declining revenue share due to biosimilar uptake.

Conclusion
The Bevacizumab Biosimilars Market is projected to grow from USD 2.7 billion in 2024 to USD 9.8 billion by 2034, at a strong CAGR of 13.5%. With rising cancer cases and increasing focus on cost containment, biosimilars offer a sustainable solution for global oncology care.

North America and Europe currently lead adoption, but Asia-Pacific will drive the next phase of growth, reshaping the competitive landscape.

Advances in manufacturing technologies, combination therapies, and regulatory approvals will accelerate market penetration, while collaborations between pharma giants and biotech firms will enhance global reach.

For healthcare providers, patients, and investors, Bevacizumab biosimilars represent a critical frontier in making life-saving cancer treatments more accessible and affordable worldwide.

This report is also available in the following languages : Japanese (ベバシズマブバイオシミラー市場), Korean (베바시주맙 바이오시밀러 시장), Chinese (贝伐珠单抗生物类似药市场), French (Marché des biosimilaires du bevacizumab), German (Markt für Bevacizumab-Biosimilars), and Italian (Mercato dei biosimilari di Bevacizumab), etc.

Request for a sample of this research report at (Use Corporate Mail ID for Quick Response) @ https://exactitudeconsultancy.com/reports/72673/bevacizumab-biosimilars-market#request-a-sample

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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
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