Press release
Elegen and Integrated DNA Technologies collaborate to transform the market for lengthy DNA synthesis
DNA synthesis
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Market Overview
The global DNA synthesis market was valued at USD 3.2 billion in 2024 and is projected to reach USD 12.6 billion by 2034, expanding at a CAGR of 14.6%.
Key Highlights:
• Market Size 2024: USD 3.2 billion
• Forecast 2034: USD 12.6 billion
• CAGR (2024-2034): 14.6%
• Growth Drivers: Expanding synthetic biology applications, rising demand for gene-based therapies, and increasing focus on personalized medicine.
• Challenges: High costs, technical complexity, and ethical concerns around genetic engineering.
• Leading Players: Thermo Fisher Scientific, Twist Bioscience, Integrated DNA Technologies (IDT), GenScript, Eurofins Genomics, DNA Script, Agilent Technologies, and BioBasic Inc.
This market is emerging as a critical enabler of next-generation healthcare and industrial biotechnology innovations.
Segmentation Analysis
By Product & Service:
• Oligonucleotide synthesis
• Gene synthesis
• Custom DNA libraries
• Reagents & consumables
• DNA synthesis software & services
By Technology:
• Solid-phase synthesis
• PCR-based enzymatic synthesis
• Chip-based DNA synthesis
• Enzymatic DNA synthesis (EDS)
• Others (ligation-based, microarray synthesis)
By Application:
• Drug discovery & development
• Genetic engineering & synthetic biology
• Diagnostics & molecular biology research
• Agricultural biotechnology
• Personalized medicine
• Vaccine development
By End-User:
• Academic & research institutes
• Pharmaceutical & biotechnology companies
• Contract research organizations (CROs)
• Diagnostic & clinical laboratories
• Agricultural and industrial biotech firms
Summary:
Drug discovery, diagnostics, and synthetic biology dominate applications, while enzymatic DNA synthesis (EDS) is expected to disrupt the market with faster, more precise, and cost-effective DNA assembly methods.
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Regional Analysis
North America
• Largest market due to advanced genomics research, early adoption of synthetic biology, and significant government funding (NIH, DARPA projects).
• The U.S. leads in DNA synthesis innovation with strong biotech and pharma presence.
Europe
• Germany, UK, and Switzerland are major hubs for genomics and synthetic biology.
• EU-funded projects on precision medicine and bioengineering boost demand.
Asia-Pacific
• Fastest-growing region, led by China, Japan, South Korea, and India.
• Rising pharmaceutical R&D investments, growing CRO industry, and government-backed biotechnology initiatives are driving growth.
Middle East & Africa
• Early adoption with expanding biotech investments in Gulf nations.
• Gradual rise in precision medicine and agricultural biotech applications.
Latin America
• Brazil and Mexico are leading markets with increasing collaborations in biotechnology and clinical research.
Summary:
North America holds the largest market share, but Asia-Pacific is projected to post the fastest CAGR (15%+), driven by cost-efficient outsourcing, growing clinical trials, and rapid biotech infrastructure expansion.
Market Dynamics
Key Growth Drivers:
• Expanding adoption of synthetic biology for healthcare, energy, and agriculture.
• Growing role of DNA synthesis in mRNA vaccines and personalized therapies.
• Rising demand for CRISPR-based gene editing requiring custom DNA sequences.
• Advances in AI-driven sequence design and automation.
Key Challenges:
• Ethical concerns around gene editing and synthetic organisms.
• High costs of large-scale, high-fidelity synthesis.
• Data storage and IP ownership issues in synthetic DNA.
Latest Trends:
• Commercialization of enzymatic DNA synthesis (EDS) for faster turnaround.
• Integration of cloud-based DNA design software with synthesis services.
• Growth in DNA data storage research as a next-gen information medium.
• Increasing partnerships between CROs, pharma companies, and DNA synthesis providers.
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Competitor Analysis
Major Players in the DNA Synthesis Market:
• Thermo Fisher Scientific - Leading supplier of synthesis reagents and oligo services.
• Twist Bioscience - Pioneer in high-throughput, chip-based DNA synthesis.
• Integrated DNA Technologies (IDT) - Specializes in oligos, gene fragments, and CRISPR products.
• GenScript - Global provider of custom gene synthesis and cloning services.
• Eurofins Genomics - Known for large-scale DNA sequencing and synthesis services.
• DNA Script - Innovator in enzymatic DNA synthesis (EDS) technology.
• Agilent Technologies - Active in gene synthesis, molecular biology tools, and sequencing.
• BioBasic Inc. - Supplier of affordable synthesis and molecular biology services.
Competitive Summary:
The market is highly competitive, driven by technological innovation and scalability. While established players dominate global sales, startups like DNA Script are disrupting with on-demand enzymatic synthesis platforms. Strategic acquisitions and collaborations are key growth strategies.
Conclusion
The DNA Synthesis Market is projected to reach USD 12.6 billion by 2034, driven by exponential advances in genomics, drug discovery, and synthetic biology. From vaccine development to DNA data storage, synthesis technologies are fueling innovations across industries.
Key Takeaways:
• Market to grow at 14.6% CAGR (2024-2034).
• Drug discovery, diagnostics, and synthetic biology are the leading applications.
• North America leads in adoption, while Asia-Pacific is the fastest-growing region.
• Enzymatic DNA synthesis and AI-driven platforms are the biggest disruptors.
• Competitive dynamics hinge on innovation, outsourcing, and scalability.
As the demand for faster, cheaper, and more accurate DNA synthesis continues to rise, this market will remain at the heart of precision medicine, biotechnology, and industrial genomics, shaping the next era of global innovation.
This report is also available in the following languages : Japanese (DNA合成市場), Korean (DNA 합성 시장), Chinese (DNA合成市场), French (Marché de la synthèse d'ADN), German (Markt für DNA-Synthese), and Italian (Mercato della sintesi del DNA), etc.
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