United States Hyperammonemia Market 2025 | Growth Drivers, Trends & Market Forecast, Competitive Landscape & Investment Opportunities

Market Size and Growth

Global Hyperammonemia Market is expected to reach at a Significant CAGR during the forecast period 2024-2031.

Key Development:

United States: Recent Industry Developments

✅ July 2025: Amogy secured an additional $23 million in venture financing, bringing its total funding to $80 million. This investment aims to accelerate the company's growth and advance its ammonia-to-power solutions.

✅ July 2025: Navigator Gas announced a joint venture with Amon Maritime to construct two ammonia-fueled liquefied ammonia carriers. The vessels, each with a capacity of 51,530 cubic meters, are scheduled for delivery in 2028.

✅ April 2025: CF Industries, JERA Co., Inc., and Mitsui & Co., Ltd. formed a joint venture to build a low-carbon ammonia plant in Louisiana. The facility, expected to start production in 2029, will have an annual capacity of 1.4 million metric tons.

Japan: Recent Industry Developments

✅ July 2025: Baker Hughes and Hanwha announced a partnership to develop small-size ammonia turbines. The agreement focuses on creating 100% ammonia combustion turbines for power generation.

✅ May 2025: Marubeni Corporation and ExxonMobil signed a long-term offtake agreement for approximately 250,000 tonnes of low-carbon ammonia annually. The ammonia will be supplied to Kobe Power Plant, a subsidiary of Kobe Steel, Ltd.

✅ April 2025: Six Japanese companies signed a non-binding Memorandum of Understanding to explore investment in a green ammonia production project in eastern India. This initiative aims to create Japan's first green ammonia import route.

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Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia in the blood, often due to liver dysfunction or genetic enzyme deficiencies. It can cause neurological symptoms such as confusion, lethargy, and in severe cases, coma. Management includes dietary restrictions, medications to reduce ammonia levels, and treatment of underlying causes.

Recent Mergers and Acquisitions:

United States: Recent M&A Developments

✅ July 2025: Yara International announced plans to invest in U.S. ammonia projects as part of a broader strategy to enhance shareholder returns and revamp its ammonia portfolio. This initiative aims to strengthen Yara's financial position amid tightening nitrogen markets.

✅ December 2024: Woodside Energy acquired an ammonia plant under construction in Beaumont, Texas, from OCI Global for $2.35 billion. The facility, expected to produce 1.1 million metric tons of ammonia annually, integrates low-carbon hydrogen production and carbon capture technology.

Japan: Recent M&A Developments

✅ July 2025: ACME Group announced a joint venture with Japan's IHI Corporation to develop India's largest green ammonia project in Gopalpur, Odisha. This collaboration aims to advance clean energy initiatives and support India's decarbonization efforts.

Key Players:

=> Bausch Health Companies Inc., Recordati Rare Diseases Inc., Medunik USA, Pfizer Inc., Manus Aktteva Biopharma LLP, Wellona Pharma, Merck KGaA, Biobrick Pharma, Asterisk Laboratories Pvt. Ltd, and Orpharma Pty Ltd among others.

Growth Forecast Projected:

The Global Hyperammonemia Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Hyperammonemia Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Type: Acute Hyperammonemia, Chronic Hyperammonemia

➥ By Treatment: Intravenous Infusion, Oral Medication, Dietary Supplements

➥ By Route of Administration: Intravenous, Oral

➥ By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Regional Analysis for Hyperammonemia Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Hyperammonemia producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Hyperammonemia revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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