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Digitalization Revolutionizes Biomanufacturing: Advanced Platforms Drive Operational Excellence, Visibility, and Control Across Bioprocessing Operations

09-25-2025 02:45 PM CET | Health & Medicine

Press release from: Roots Analysis

Digitalization Revolutionizes Biomanufacturing: Advanced

Recognizing the potential of digitalization, biomanufacturers are increasingly adopting advanced platforms that enable operational excellence, enhance visibility, improve control, and synchronization across their bioprocessing operations

Biomanufacturing refers to a standardized process that utilizes microorganisms and other biological systems to produce and develop biomolecules as therapeutic modalities. Traditionally, the biopharmaceutical companies have hesitated to adopt cutting-edge digital technologies, such as cloud computing, artificial intelligence (AI), machine learning and internet of things (IoT), in the field of bioprocessing.

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The global digital biomanufacturing market, valued at $2.0 billion in 2024, is projected to reach $2.4 billion in 2025 and $12.0 billion by 2035, representing a CAGR of 18% during the forecast period.

This reluctance can be attributed to the lack of technical know-how, complex regulatory requirements and a higher financial burden associated with their adoption. However, the advantages associated with the digital biomanufacturing (such as enhanced process optimization, increased staff safety, environmental sustainability, and consistent product quality) has led the pharmaceutical companies to explore the potential of digital innovations / technologies in bioprocessing.
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In recent years, it has been demonstrated that the use of digitalization in manufacturing process can boost the productivity of the process and longevity of existing infrastructure. The advantages offered by such solutions are expected to increase manifolds, as several advancements are currently being evaluated, including improved process visualization, data collation, data integration, data handling, process connectivity, process intelligence, data analytics, process control algorithms, and automation.

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Digital biomanufacturing harnesses the advancements that have been made in data analytics and IoT domain to transform information into actionable insights. However, it also means that a process network has to be built at a high level for data analysis, information management and process control.

The digital biomanufacturing software enhances asset availability and reliability while reducing maintenance needs. It is worth highlighting that digital biomanufacturing also offers real-time process optimization based on factors, such as anticipated product quality and batch profitability. Notably, process optimization is one of the critical factors to be considered since both upstream and downstream processing must sustain the unique requirements of living cells and their products. Moreover, in order achieve excellence in the process optimization, digital biomanufacturing software facilitates a comprehensive understanding of entire biomanufacturing process by integrating physical processes with the digital domain.

During the research, it was identified more than 135 digital technologies / software, developed by various industry stakeholders to enable digitalization in the biomanufacturing industry. The market landscape is fragmented, featuring the presence of both start-ups and well-established companies offering different types of technologies for digital biomanufacturing. Notably, digital biomanufacturing is dominated by small and mid-sized companies, which is indicative of the fact that this domain is currently evolving and offers opportunities for innovation and growth to the players emerging in this domain.

Close to 95% of the process analytical technologies are capable of offering process automation; of these, 30% technologies have been developed to be deployed on-premises. Further, it is worth mentioning that majority of the manufacturing execution systems can be integrated with various technologies, enabling functions such as data control, production tracking, performance analysis, and data integration.

Contact Details
Gaurav Chaudhary
Email: Gaurav.chaudhary@rootsanalysis.com or sales@rootsanalysis.com
Website: https://www.rootsanalysis.com

About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. All reports provided by us are structured in a way that enables the reader to develop a thorough perspective on the given subject. Apart from writing reports on identified areas, we provide bespoke research / consulting services dedicated to serve our clients in the best possible way.

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