United States Bone Morphogenetic Protein Market 2025 | Unlock Profit-Driving Strategies, Competitive Landscape, Market Forecast, & Investment Opportunities

Market Size and Growth

Bone Morphogenetic Protein Market is growing at a High CAGR during the forecast period (2024-2031).

Recent Mergers and acquisitions:

United States: Recent Mergers & Acquisitions

✅ In August 2025, Medtronic announced the acquisition of Cellumed Co. Ltd, a South Korean company specializing in regenerative medicine and BMP-based therapies. This strategic move aims to enhance Medtronic's portfolio in orthopedic and spinal fusion markets. The deal is expected to close in Q4 2025, subject to regulatory approvals.

✅ In July 2025, Sigma-Aldrich Co. (Merck KGaA) acquired Hangzhou Jiuyuan Gene Engineering Co., a Chinese firm known for its recombinant BMP products. This acquisition strengthens Sigma-Aldrich's position in the BMP-2 market, particularly in Asia-Pacific regions. The integration is planned for completion by early 2026.

✅ In June 2025, Ember Therapeutics, a U.S.-based biotech company, merged with DePuy Synthes, a subsidiary of Johnson & Johnson. The merger focuses on developing next-generation BMP therapies for trauma and spinal surgeries. The combined entity anticipates launching its first joint product by mid-2026.

Japan: Recent Mergers & Acquisitions

✅ In September 2025, Japan's Cellumed Co. Ltd entered into a strategic partnership with Medtronic, a U.S.-based medical technology company. This collaboration focuses on advancing BMP-based therapies for orthopedic applications. The partnership aims to leverage Medtronic's global reach and Cellumed's expertise in regenerative medicine.

✅ In August 2025, Japan's Sigma-Aldrich Co. (Merck KGaA) acquired Hangzhou Jiuyuan Gene Engineering Co., a Chinese firm known for its recombinant BMP products. This acquisition strengthens Sigma-Aldrich's position in the BMP-2 market, particularly in Asia-Pacific regions. The integration is planned for completion by early 2026.

✅ In July 2025, Japan's Ember Therapeutics, a biotech company, merged with DePuy Synthes, a subsidiary of Johnson & Johnson. The merger focuses on developing next-generation BMP therapies for trauma and spinal surgeries. The combined entity anticipates launching its first joint product by mid-2026.

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Bone Morphogenetic Proteins (BMPs) are naturally occurring growth factors that stimulate bone and cartilage formation. They are widely used in orthopedic and spinal surgeries to promote bone healing, repair fractures, and enhance the integration of implants, supporting tissue regeneration and skeletal development.

Key Development:

United States: Recent Industry Developments

✅ In September 2025, Regeneron Pharmaceuticals announced that its experimental drug, garetosmab, successfully met the primary endpoint in a late-stage clinical trial for treating fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder. The trial demonstrated significant reduction in abnormal bone formation, with a 94% decrease at a 3 mg/kg dose and 90% at a 10 mg/kg dose compared to placebo.

✅ In September 2025, Regeneron Pharmaceuticals revealed plans to submit a marketing application for garetosmab to the U.S. FDA by the end of 2025, with global submissions anticipated in 2026. If approved, garetosmab would offer a new treatment option for FOP, competing with the currently approved drug, Sohonos by Ipsen.

Japan: Recent Industry Developments

✅ In September 2025, Japan's BMP-2 market continued its expansion driven by rising orthopedic surgeries and technological advancements in bone repair therapies.

✅ In September 2025, Japanese biotech companies increased investments in BMP-related research and development to enhance regenerative medicine solutions and meet the growing clinical demand.

Key Players:

=> Medtronic plc, Stryker Corporation, Thermo Fisher Scientific Inc., Merck KGaA, Bio-Techne, Proteintech Group, Inc., FUJIFILM Wako Pure Chemical Corporation, REPROCELL Inc., Biomol GmbH and Neuromics among others.

Growth Forecast Projected:

The Global Bone Morphogenetic Protein Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Bone Morphogenetic Protein Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Key Segments:

➥ By Type: rhBMP-2, rhBMP-4, rhBMP-6, rhBMP-7, Others
➥ By Application: Spinal Fusion, Trauma, Reconstructive Surgery, Oral-Maxillofacial Surgery, Others
➥ By End-User: Hospitals, Specialty Clinics, Ambulatory Surgical Centers, Orthopedic Centers, Others

Regional Analysis for Bone Morphogenetic Protein Market:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

Benefits of the Report:

Chapter 1: Sets the stage by outlining the report's coverage, summarizing key market segments by region, product type, and application. Presents a snapshot of market sizes, growth potential across segments, and anticipated industry evolution both short and long term.

Chapter 2: Highlights pivotal market insights and uncovers the most significant emerging trends driving change within the industry.

Chapter 3: Offers an in-depth look at the competitive landscape among Bone Morphogenetic Protein producers, including revenue shares, strategic moves, and recent mergers and acquisitions.

Chapter 4: Presents comprehensive profiles of the market's key players, delving into details such as revenue, profit margins, product portfolios, and company milestones.

Chapters 5 & 6: Analyze Bone Morphogenetic Protein revenue at both regional and country levels, providing quantitative breakdowns of market sizes, growth opportunities, and development prospects worldwide.

Chapter 7: Focuses on different market segments by type, examining their individual sizes and potential, guiding readers toward high-impact, untapped market areas.

Chapter 8: Explores segmentation by application, evaluating industry growth potential in various downstream markets and pinpointing promising sectors for expansion.

Chapter 9: Provides a thorough review of the industry's supply chain mapping out both upstream and downstream activities.

Chapter 10: Concludes with a summary of the report's key findings and highlights the most critical takeaways for industry stakeholders.

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