NGS-Based RNA-Sequencing Market Enhancing Transcriptome Profiling and Personalized Medicine Innovations

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global NGS-Based RNA-Sequencing Market Size, Share & Trends Analysis Report By Type (Targeted RNA Sequencing, mRNA Sequencing, Total RNA Sequencing, Single-cell RNA Sequencing (scRNA-Seq), De Novo Transcriptome Assembly , and Non-coding RNA Sequencing (miRNA, lncRNA, circRNA)), Workflow Component (Sequencing, Library Preparation & Sample Processing, Storage & Cloud Bioinformatics, and Data Analysis & Interpretation), Technology (Sequencing by Synthesis (SBS), Third-generation Sequencing (PacBio, ONT), Ion Semiconductor Sequencing, Nanopore Sequencing (Oxford Nanopore), and SOLiD & Pyrosequencing (legacy/declining)), Application (Precision Medicine, Drug Discovery & Development, Cancer Genomics, Disease Mechanism Studies, Biomarker Discovery, Single-Cell Transcriptomics in Immuno-Oncology, Plant and Microbial Transcriptomics), End-user (Pharmaceutical & Biotechnology Companies, Academic & Research Institutions, Contract Research Organizations (CROs), Government and Non-profit Organizations, Clinical & Diagnostic Laboratories),-Market Outlook And Industry Analysis 2034"

The Global NGS-Based RNA-Sequencing Market is valued at US$ 3.6 Bn in 2024 and it is expected to reach US$ 20.3 Bn by the year 2034 , with a CAGR of 19.2% during the forecast period of 2025-2034.

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Next-generation sequencing (NGS) of ribonucleic acid (RNA) is an advanced technique employed to detect and analyze RNA within a given sample. By leveraging NGS-based RNA sequencing, researchers can comprehensively examine the transcriptome, providing insights into the complete set of RNA molecules present.

The resulting data enables detailed analysis of gene expression, identification of novel transcripts, and detection of potential mutations, supporting a deeper understanding of biological processes at the molecular level. The expansion of the NGS-based RNA sequencing market is being driven by increasing demand for transcriptome profiling, the rising adoption of precision medicine, and continuous advancements in high-throughput sequencing technologies.

Furthermore, the market is expected to grow over the forecast period, fueled by a surge in product approvals and the introduction of RNA-sequencing platforms and consumables. The increasing focus on transcriptomic and whole-genome analyses to enable personalized medicine is further strengthening market demand.

Additionally, the application of NGS-based RNA sequencing in drug development, biomarker discovery, and disease diagnostics is contributing to its rising adoption. Key market participants, including BGI Genomics, Illumina, and Roche, are actively investing in technological advancements to enhance RNA sequencing capabilities, further supporting market growth.

List of Prominent Players in the NGS-Based RNA-Sequencing Market:
• Agilent Technologies
• QIAGEN
• Illumina, Inc.
• Thermo Fisher Scientific
• Takara Bio Inc.
• 10x Genomics
• Oxford Nanopore Technologies
• Pacific Biosciences (PacBio)
• BGI Genomics
• Novogene Corporation
• Eurofins Genomics
• Bio-Rad Laboratories
• Genewiz (Azenta Life Sciences)
• Parse Biosciences
• PerkinElmer (Revvity)
• CD Genomics
• Fulgent Genetics
• Macrogen Inc.
• Element Biosciences

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Market Dynamics:
Drivers:
The NGS-based RNA-sequencing market is witnessing rapid expansion driven by several key factors. The increasing demand for personalized medicine is a primary growth driver, as it necessitates advanced genomic analysis to tailor therapies to individual genetic profiles. Declining costs of sequencing technologies are further facilitating market growth by making RNA sequencing more accessible and cost-effective for both clinical and research applications.

The market is also bolstered by a surge in cancer research initiatives, as RNA sequencing offers unparalleled insights into tumor biology and biomarker discovery. In addition, the growing application of RNA sequencing in agricultural biotechnology-enabling enhanced crop yields and improved resilience-presents further growth opportunities.

Challenges:
Despite its growth prospects, the market faces several challenges. High sequencing costs limit access for smaller laboratories and institutions, resulting in market concentration among well-funded organizations. The complexity of data analysis and interpretation requires specialized expertise, creating potential bottlenecks in processing workflows.

Additionally, the absence of standardized protocols can lead to variability across studies, affecting reproducibility. Intellectual property considerations, including navigating complex patent landscapes, further add to operational and financial challenges.

Regional Trends:
In 2024, North America dominated the NGS-based RNA-sequencing market, supported by a robust ecosystem of leading universities, research institutions, and biotechnology companies, particularly in the United States. The region's innovation-friendly environment and rapid adoption of NGS technologies, combined with substantial public and private investment in biotechnology and healthcare, have reinforced its market leadership.

Over the forecast period, the Asia Pacific region is expected to register the highest compound annual growth rate (CAGR). Accelerated investments and government initiatives aimed at strengthening healthcare infrastructure are fueling regional market expansion. The adoption of advanced technologies, including NGS-based RNA sequencing, for research and diagnostics is being actively promoted. Furthermore, the growing emphasis on precision medicine-leveraging genetic insights for patient-specific therapies-is driving increased utilization of RNA sequencing in the region, particularly for studying genetic variations and disease mechanisms.

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Segmentation of NGS-Based RNA-Sequencing Market-
By Type-
• Targeted RNA Sequencing
• mRNA Sequencing
• Total RNA Sequencing
• Single-cell RNA Sequencing (scRNA-Seq)
• De Novo Transcriptome Assembly
• Non-coding RNA Sequencing (miRNA, lncRNA, circRNA)
By Workflow Component -
• Sequencing
• Library Preparation & Sample Processing
• Storage & Cloud Bioinformatics
• Data Analysis & Interpretation
By Technology-
• Sequencing by Synthesis (SBS)
• Third-generation Sequencing (PacBio, ONT)
• Ion Semiconductor Sequencing
• Nanopore Sequencing (Oxford Nanopore)
• SOLiD & Pyrosequencing (legacy/declining)
By Application-
• Precision Medicine
• Drug Discovery & Development
• Cancer Genomics
• Disease Mechanism Studies
• Biomarker Discovery
• Single-Cell Transcriptomics in Immuno-Oncology
• Plant and Microbial Transcriptomics
By End-user-
• Pharmaceutical & Biotechnology Companies
• Academic & Research Institutions
• Contract Research Organizations (CROs)
• Government and Non-profit Organizations
• Clinical & Diagnostic Laboratories
By Region-
North America-
• The US
• Canada
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Mexico
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa

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This release was published on openPR.