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Steady Expansion Forecast for Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market, Projected to Reach $6.09 Billion by 2029

09-16-2025 08:49 AM CET | Health & Medicine

Press release from: The Business Research Company

Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market

Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market

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Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
There has been a significant increase in the size of the adeno-associated virus (avv) vectors in the gene therapy market in recent years. The market, which was worth $2.7 billion in 2024, is predicted to rise to $3.16 billion in 2025, with a compound annual growth rate (CAGR) of 16.7%. The previously observed growth can be attributed to factors such as the increase in gene therapy research investments, the rising usage of gene editing technologies, growth in genetic disorders and unfulfilled medical needs, escalating demand for targeted therapies, and a rise in the collaboration between biotech firms and research institutes.

Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Size Forecast: What's the Projected Valuation by 2029?
In the coming years, the market size for adeno-associated virus (AVV) vectors in gene therapy is projected to experience rapid growth, with an expectation to reach $6.09 billion in 2029 at a compound annual growth rate of 17.6%. This predicted growth in the forecast period can be credited to multiple factors, including the rise in advancements in AAV capsid engineering, an increased focus on precision medicine, amplified investments in the sectors of genetic research and biotechnology, an upswing in the number of clinical trials and approvals for gene therapy, and a growing demand for tailored treatments. Prominent trends in the prediction timeline include the advancements in artificial intelligence usage for AAV capsid engineering, the emergence of hybrid AAV vectors for larger genetic payloads, innovations in AAV targeting through bispecific antibody-mediated, developments in AAV production and purification methodologies that can be scaled up, and the creation of adaptable AAV platforms that can accommodate a variety of viral vectors.

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What Are the Drivers Transforming the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
The escalating emphasis on therapies centered around genes is predicted to fuel the expansion of the adeno-associated virus (AAV) vectors within the gene therapy market in the future. Gene-centered therapies are procedures that adjust or influence genes to preempt, remedy, or eradicate diseases at the molecular scale. Progressions in genetic examination are responsible for the intensified emphasis on developing gene-based therapies, as they amplify the accuracy and effectivity of gene alteration techniques. Adeno-associated virus (AAV) vectors in gene therapy contribute to the creation of gene-based therapies by securely and effectively transporting curative genes into desired cells, with benefits such as decreased immunogenicity and long-term gene expression. For example, as per IQVIA, an American firm that offers superior analytics and technological resolutions for the life sciences sector, global expenditure on cell and gene therapies was $5.9 billion in 2023, revealing a 38% surge from 2022. Consequently, the amplified emphasis on developing gene-based therapies is fostering the expansion of the adeno-associated virus (AAV) vectors market.

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What Are the Key Trends Driving Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Growth?
Leading corporations in the gene therapy market for adeno-associated virus (AAV) vectors are directing their attention towards advanced innovation, such as customised vector diversity for assay adaptability. This aids in increasing target tissue preciseness, bettering therapeutic efficiency, and speeding up the creation of personalized gene therapies for a range of indications. Customised vector diversity for assay adaptability means utilizing various AAV serotypes or designs to provide support for a plethora of analytical tests and therapeutic uses. For example, in May 2024, a pharmaceutical company based in the US called Charles River Laboratories introduced newer reference materials for both AAV and Lentiviral vectors (LVV). These materials are designed to back the increasing demands of development in cell and gene therapy (CGT). The portfolio enables a more seamless move from primary research to GMP-grade production and helps to standardize methods and enhance regularity in viral vector production. This launch effectively tackles a significant hurdle in escalating CGT programs towards readiness for clinical and commercial purposes.

Which Segments in the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Offer the Most Profit Potential?
The adeno-associated virus (avv) vectors in gene therapy market covered in this report is segmented -

1) By Type of Therapy: Gene Augmentation, Immunotherapy, Other Type of Therapy
2) By Type of Gene Delivery Method Used: Ex Vivo, In Vivo
3) By Scale of Operation: Preclinical, Clinical, Commercial
4) By Target Therapeutic Area: Genetic Disorders, Hematological Disorders, Infectious Diseases, Metabolic Disorders, Ophthalmic Disorders, Muscle Disorders, Neurological Disorders, Other Target Therapeutic Area

Subsegments:
1) By Gene Augmentation: Monogenic Disorders, Neurological Disorders, Muscular Disorders, Ophthalmological Disorders, Metabolic Disorders
2) By Immunotherapy: Oncology, Infectious Diseases, Autoimmune Disorders, Vaccine Development, T-Cell Engineering
3) By Other Type of Therapy: Gene Editing Support, RNA Interference, Neuroprotection and Neuroregeneration, Anti-Inflammatory Applications, Regenerative Medicine

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Which Firms Dominate the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market by Market Share and Revenue in 2025?
Major companies operating in the adeno-associated virus (AVV) vectors in gene therapy market are F. Hoffmann-La Roche Ltd., Sanofi S.A., Novartis AG, Astellas Gene Therapies Inc., Biogen Inc., Sarepta Therapeutics Inc., Oxford BioMedica plc, Rocket Pharmaceuticals Inc., Aldevron LLC, REGENXBIO Inc., uniQure N.V., Passage Bio Inc., Voyager Therapeutics Inc., Dyno Therapeutics Inc., MeiraGTx Holdings plc, Abeona Therapeutics Inc., 4D Molecular Therapeutics Inc., GenSight Biologics S.A., Taysha Gene Therapies Inc., LogicBio Therapeutics Inc.

Which Regions Offer the Highest Growth Potential in the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
North America was the largest region in the adeno-associated virus (AVV) vectors in gene therapy market in 2024. The regions covered in the adeno-associated virus (AVV) vectors in gene therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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