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Autologous Stem Cell And Non-Stem Cell Based Therapies Market Trends That Will Shape the Next Decade: Insights from Advancements In Autologous T-cell Immunotherapy

09-15-2025 09:53 AM CET | Health & Medicine

Press release from: The Business Research Company

Autologous Stem Cell And Non-Stem Cell Based Therapies Market

Autologous Stem Cell And Non-Stem Cell Based Therapies Market

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How Large Will the Autologous Stem Cell And Non-Stem Cell Based Therapies Market Size By 2025?
There has been a swift expansion in the market size of autologous stem cell and non-stem cell based therapies in the last few years. It is projected to increase from $9.96 billion in 2024 to $11.49 billion in 2025, marking a compound annual growth rate (CAGR) of 15.5%. Factors such as the growing incidence of cancer and diabetes, an increasing geriatric population, heightened awareness about healthcare, a surge in research and development activities, a rise in clinical trials, and more regulatory approvals have largely contributed to this growth during the historic period.

How Big Is the Autologous Stem Cell And Non-Stem Cell Based Therapies Market Size Expected to Grow by 2029?
The market size for autologous stem cell and non-stem cell based therapies is predicted to experience significant growth in the forthcoming years. It is projected to escalate to "$20.07 billion by 2029 with a compound annual growth rate (CAGR) of 15.0%. The surge during the forecast period can be associated with factors such as the escalating incidence of specific diseases, the growing older population, the increasing frequency of neurodegenerative diseases, the rising number of cancer incidents, the heightened demand for skin transplants, greater awareness of regenerative medicine, and collaborations and partnerships among leading entities. The reimbursement for approved therapies is also getting better. Major trends during this forecast period encompass the incorporation of artificial intelligence and machine learning, the creation of ready-to-use allogeneic stem cell products, the enlargement of reimbursement policies, the adaptation of innovative biomaterials, advances in cell production technologies, the acceptance of autologous stem cell therapies, and the incorporation of gene editing technologies.

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Which Key Market Drivers Powering Autologous Stem Cell And Non-Stem Cell Based Therapies Market Expansion and Growth?
The growth of the autologous stem cell and non-stem cell-based therapies market is suspected to be bolstered by the increasing demand for personalized therapies. These treatments are developed to optimize benefits and decrease adverse consequences, taking into account a patient's unique genetic makeup, lifestyle, and preferences. Numerous factors, including advancements in genetics and technology which facilitate more accurate and successful treatments with fewer side effects, a rise in patient requests for personalized healthcare, and the possibility of reducing healthcare costs, are driving these personalized therapies. Customizing autologous stem cell and non-stem cell-based therapies to match a person's distinctive genetic and health traits improves their application, leading to superior results and reduced complications. For example, the Personalized Medicine Coalition, a professional membership organization in the US, noted that in 2022, 12 newly approved personalized medicines made up approximately 34% of all newly approved treatments. This represents a significant leap from previous years. For these reasons, the desire for personalized therapies is a major growth influencer for the autologous stem cell and non-stem cell-based therapies market.

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What Long-Term Trends Will Define the Future of the Autologous Stem Cell And Non-Stem Cell Based Therapies Market?
Leading businesses in the autologous stem cell and non-stem cell-based therapies market are advancing autologous T cell immunotherapy derived from tumors to improve personalized methods for cancer treatment. This type of immunotherapy involves extracting T cells from a patient's tumor, cultivating and activating them in a lab, and then reintroducing them back into the patient to strengthen their immune system's capability to specifically identify and eliminate cancer cells. For example, in February 2024, Iovance Biotherapeutics, an American biotechnology firm, gained expedited approval from the US-based Food and Drug Administration for Amtagvi (lifileucel), which marks the first cellular therapy prescribed for treating adult patients suffering from melanoma. Lifileucel, a immunotherapy based on autologous T-cells derived from tumors, consists of the patient's naturally occurring immune cells known as tumor-infiltrating lymphocytes (TILs). This enhances the immune system's ability of the patient to effectively recognize and combat the cancer.

What Are the Emerging Segments in the Autologous Stem Cell And Non-Stem Cell Based Therapies Market?
The autologous stem cell and non-stem cell based therapies market covered in this report is segmented -

1) By Type: Autologous Stem Cells, Autologous Non-Stem Cells, Other Types
2) By Application: Cancer, Neurodegenerative Disorders, Cardiovascular Disease, Orthopedic Diseases, Other Applications
3) By End-User: Hospitals, Ambulatory Surgical Centers, Research Facilities, Other End Users

Subsegments:
1) By Autologous Stem Cells: Hematopoietic Stem Cells, Mesenchymal Stem Cells, Neural Stem Cells, Endothelial Stem Cells
2) By Autologous Non-Stem Cells: Platelet-Rich Plasma (Prp), Adipose-Derived Cells, Peripheral Blood Cells
3) By Other Types: Exosome-Based Therapies, Tissue-Engineered Constructs

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Who Are the Global Leaders in the Autologous Stem Cell And Non-Stem Cell Based Therapies Market?
Major companies operating in the autologous stem cell and non-stem cell based therapies market are Bayer AG, Novartis AG, Takeda Pharmaceutical Company Limited, Gilead Sciences Inc., Merck & Co. Inc., Stemcell Technologies Inc., Dendreon Corporation, Vericel Corporation, Sangamo Therapeutics Inc., NEOSTEM, Orgenesis Inc., Adaptimmune Therapeutics, Stempeutics Research Pvt Ltd., MEDIPOST, Castle Creek Biosciences Inc., BrainStorm Cell Limited, Athersys Inc., Cytori Therapeutics Inc., Opexa Therapeutics, Gamida Cell, Regen BioPharma Inc., RepliCel Life Sciences, InGeneron Inc., BioCardia Inc., ReNeuron Group

Which are the Top Profitable Regional Markets for the Autologous Stem Cell And Non-Stem Cell Based Therapies Industry?
North America was the largest region in the autologous stem cell and non-stem cell based therapies market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the autologous stem cell and non-stem cell based therapies market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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