Oncolytic Virus Cancer Therapy Pipeline 2025: MOA and ROA Insights, Clinical Trials Status, and Key Companies Involved by DelveInsight | Oncolys Biopharma, Imugene, Vaxiion Therapeutics, Boehringer

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Oncolytic Virus Cancer Therapy pipeline constitutes 120+ key companies continuously working towards developing 125+ Oncolytic Virus Cancer Therapy treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Oncolytic Virus Cancer Therapy Pipeline Insight, 2025 [https://www.delveinsight.com/sample-request/oncolytic-virus-cancer-therapy-pipeline-insight-2021?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Oncolytic Virus Cancer Therapy Market.

The Oncolytic Virus Cancer Therapy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Oncolytic Virus Cancer Therapy Pipeline Report:

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Companies across the globe are diligently working toward developing novel Oncolytic Virus Cancer Therapy treatment therapies with a considerable amount of success over the years.

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Oncolytic Virus Cancer Therapy companies working in the treatment market are Oncolys Biopharma, Imugene, Vaxiion Therapeutics, Boehringer Ingelheim, Treovir, Istari Oncology, Immvira Pharma, Genelux Corporation, DNAtrix, Nouscom, Astellas Pharma, CG Oncology, Targovax, Transgene, Istari Oncology, Targovax, Oncolytics Biotech, and others, are developing therapies for the Oncolytic Virus Cancer Therapy treatment

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Emerging Oncolytic Virus Cancer Therapy therapies in the different phases of clinical trials are- OBP-702, CF33-hNIS, VAX-014, BI-1831169, G207, PVSRIPO, MVR-T3011, Olvi-Vec, DNX 2440, NOUS PEV, ASP 9801, CG0070, ONCOS-102, TG 6002, PVS-RIPO, DNX-2401, ONCOS 102, Pelareorep, CG0070, and others are expected to have a significant impact on the Oncolytic Virus Cancer Therapy market in the coming years.

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In August 2025, Genelux Corporation announced the OnPrime study, a multi-center, randomized, open-label Phase 3 trial assessing the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab, compared to the Active Comparator Arm with physician's choice of chemotherapy and bevacizumab, in women with platinum-resistant or refractory ovarian cancer, including fallopian tube and primary peritoneal cancers.

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In March 2025, Genelux Corporation reported initial safety and anti-tumor activity results from the dose-escalation Phase 1b segment of its co-sponsored ongoing Phase Ib/II trial (OLVI-VEC-SCLC202), evaluating Olvi-Vec immunochemotherapy in patients with platinum-relapsed or platinum-refractory extensive small cell lung cancer.

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In November 2024, Mustang Bio, Inc. (Nasdaq: MBIO), a clinical-stage biopharmaceutical company dedicated to advancing cell therapies for challenging cancers, announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to Mustang for MB-108, a herpes simplex virus type 1 (HSV-1) oncolytic virus, for the treatment of malignant glioma.

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In July 2024, KaliVir Immunotherapeutics announced FDA clearance of the Investigational New Drug (IND) application for the STEALTH-001 trial of VET3-TGI in patients with advanced, incurable solid tumors.

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In April 2024, Replimune has shared interim findings from ARTACUS, a Phase I/II clinical trial evaluating RP1 monotherapy for skin cancers in patients who have received solid organ or hematopoietic cell transplants. Currently, RP1 is being tested in the Phase II IGNYTE study, a multi-cohort clinical trial that combines RP1 with OPDIVO.

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In March 2024, The FDA has granted fast track designation to MVR-T3011, an oncolytic virus product administered via intratumoral injection, for treating patients with recurrent or metastatic HNSCC whose disease has progressed after platinum-based chemotherapy and at least one prior line of anti-PD-1/PD-L1 therapy. MVR-T3011 is a proprietary 3-in-1 oncolytic virus developed by ImmVira. This genetically engineered agent aims to combine the most beneficial features of attenuated HSV-1, including replication potency in tumor cells and limited replication in normal cells. It functions by incorporating a PD-1 antibody and IL-12, which further enhances immune responses within the tumor microenvironment.

Oncolytic Virus Cancer Therapy Overview

Oncolytic virus cancer therapies are virus-based treatment modalities that infect and kill cancer cells, and by releasing tumor-specific antigens, also serve as an in situ cancer vaccine. Myxoma virus and reovirus are two examples of viruses that naturally target tumour cells while being nonpathogenic to healthy human cells.

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Emerging Oncolytic Virus Cancer Therapy Drugs Under Different Phases of Clinical Development Include:

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OBP-702: Oncolys Biopharma

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CF33-hNIS: Imugene

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VAX-014: Vaxiion Therapeutics

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BI-1831169: Boehringer Ingelheim

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G207: Treovir

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PVSRIPO: Istari Oncology

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MVR-T3011: Immvira Pharma

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Olvi-Vec: Genelux Corporation

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DNX 2440: DNAtrix

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NOUS PEV: Nouscom

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ASP 9801:Astellas Pharma

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CG0070: CG Oncology

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ONCOS-102: Targovax

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TG 6002 : Transgene

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PVS-RIPO: Istari Oncology

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DNX-2401: DNAtrix

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ONCOS 102: Targovax

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Pelareorep: Oncolytics Biotech

Oncolytic Virus Cancer Therapy Route of Administration

Oncolytic Virus Cancer Therapy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as

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Intranasal

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Intravenous

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Oral

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Oral/Intravenous

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Parenteral

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Subcutaneous

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Subcutaneous/Intramuscular

Oncolytic Virus Cancer Therapy Molecule Type

Oncolytic Virus Cancer Therapy Products have been categorized under various Molecule types, such as

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Oncolytic Viruse

Oncolytic Virus Cancer Therapy Pipeline Therapeutics Assessment

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Oncolytic Virus Cancer Therapy Assessment by Product Type

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Oncolytic Virus Cancer Therapy By Stage and Product Type

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Oncolytic Virus Cancer Therapy Assessment by Route of Administration

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Oncolytic Virus Cancer Therapy By Stage and Route of Administration

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Oncolytic Virus Cancer Therapy Assessment by Molecule Type

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Oncolytic Virus Cancer Therapy by Stage and Molecule Type

DelveInsight's Oncolytic Virus Cancer Therapy Report covers around 125+ products under different phases of clinical development like

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Late-stage products (Phase III)

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Mid-stage products (Phase II)

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Early-stage product (Phase I)

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Pre-clinical and Discovery stage candidates

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Discontinued & Inactive candidates

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Route of Administration

Further Oncolytic Virus Cancer Therapy product details are provided in the report. Download the Oncolytic Virus Cancer Therapy pipeline report to learn more about the emerging Oncolytic Virus Cancer Therapy therapies [https://www.delveinsight.com/sample-request/oncolytic-virus-cancer-therapy-pipeline-insight-2021?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Some of the key companies in the Oncolytic Virus Cancer Therapy Therapeutics Market include:

Key companies developing therapies for Oncolytic Virus Cancer Therapy are - Lokon Pharma, Merck, Wuhan Binhui Biotechnology, CG Oncology, Oncolys Biopharma, Replimune, Transgene, Sorrento Therapeutics, ORCA Therapeutics, TILT Biotherapeutics, BioEclipse Therapeutics, Oncolytics Biotech, Oncorus, DNAtrix, OncoMyx Therapeutics, Vyriad, Boehringer Ingelheim, IconOVir Bio, Imugene, Turnstone Biologics, Immvira Pharma, SillaJen Biotherapeutics, Advantagene, Nouscom, TOT Biopharm, Elicera Therapeutics, Takeda, Candel Therapeutics, Valo Therapeutics, Tessa Therapeutics, PsiOxus Therapeutics, KaliVir Immunotherapeutics, Oncos Therapeutics, Mustang Bio, Takara Bio, Vaxiion Therapeutics, Synthetic Biologics, Calidi Biotherapeutics, Genelux Corporation, Shanghai Sunway Biotech, BioInvent International AB, Guizhou Sinorda Biomedicine, EpicentRx, Hookipa Pharma Inc., Imvaq Therapeutics, Seneca Therapeutics, AmunBio, Orgenesis, Protheragen, Astellas Pharma, and others.

Oncolytic Virus Cancer Therapy Pipeline Analysis:

The Oncolytic Virus Cancer Therapy pipeline report provides insights into

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The report provides detailed insights about companies that are developing therapies for the treatment of Oncolytic Virus Cancer Therapy with aggregate therapies developed by each company for the same.

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It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Oncolytic Virus Cancer Therapy Treatment.

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Oncolytic Virus Cancer Therapy key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

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Oncolytic Virus Cancer Therapy Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

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Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Oncolytic Virus Cancer Therapy market.

The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about Oncolytic Virus Cancer Therapy drugs and therapies [https://www.delveinsight.com/sample-request/oncolytic-virus-cancer-therapy-pipeline-insight-2021?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Oncolytic Virus Cancer Therapy Pipeline Market Drivers

Increase in the number of patients with cancers, rising need for advanced and effective cancer therapeutics for improved quality of life are some of the important factors that are fueling the Oncolytic Virus Cancer Therapy Market.

Oncolytic Virus Cancer Therapy Pipeline Market Barriers

However, lack of development, scaleup and commercialisation resources available to developers, lack of awareness about the new class of anticancer immunotherapy and other factors are creating obstacles in the Oncolytic Virus Cancer Therapy Market growth.

Scope of Oncolytic Virus Cancer Therapy Pipeline Drug Insight

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Coverage: Global

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Key Oncolytic Virus Cancer Therapy Companies: Oncolys Biopharma, Imugene, Vaxiion Therapeutics, Boehringer Ingelheim, Treovir, Istari Oncology, Immvira Pharma, Genelux Corporation, DNAtrix, Nouscom, Astellas Pharma, CG Oncology, Targovax, Transgene, Istari Oncology, Targovax, Oncolytics Biotech, and others

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Key Oncolytic Virus Cancer Therapy Therapies: OBP-702, CF33-hNIS, VAX-014, BI-1831169, G207, PVSRIPO, MVR-T3011, Olvi-Vec, DNX 2440, NOUS PEV, ASP 9801, CG0070, ONCOS-102, TG 6002, PVS-RIPO, DNX-2401, ONCOS 102, Pelareorep, CG0070, and others

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Oncolytic Virus Cancer Therapy Therapeutic Assessment: Oncolytic Virus Cancer Therapy current marketed and Oncolytic Virus Cancer Therapy emerging therapies

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Oncolytic Virus Cancer Therapy Market Dynamics: Oncolytic Virus Cancer Therapy market drivers and Oncolytic Virus Cancer Therapy market barriers

Request for Sample PDF Report for Oncolytic Virus Cancer Therapy Pipeline Assessment and clinical trials [https://www.delveinsight.com/sample-request/oncolytic-virus-cancer-therapy-pipeline-insight-2021?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Table of Contents

1. Oncolytic Virus Cancer Therapy Report Introduction

2. Oncolytic Virus Cancer Therapy Executive Summary

3. Oncolytic Virus Cancer Therapy Overview

4. Oncolytic Virus Cancer Therapy- Analytical Perspective In-depth Commercial Assessment

5. Oncolytic Virus Cancer Therapy Pipeline Therapeutics

6. Oncolytic Virus Cancer Therapy Late Stage Products (Phase II/III)

7. Oncolytic Virus Cancer Therapy Mid Stage Products (Phase II)

8. Oncolytic Virus Cancer Therapy Early Stage Products (Phase I)

9. Oncolytic Virus Cancer Therapy Preclinical Stage Products

10. Oncolytic Virus Cancer Therapy Therapeutics Assessment

11. Oncolytic Virus Cancer Therapy Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Oncolytic Virus Cancer Therapy Key Companies

14. Oncolytic Virus Cancer Therapy Key Products

15. Oncolytic Virus Cancer Therapy Unmet Needs

16 . Oncolytic Virus Cancer Therapy Market Drivers and Barriers

17. Oncolytic Virus Cancer Therapy Future Perspectives and Conclusion

18. Oncolytic Virus Cancer Therapy Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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