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US Ophthalmology Amniotic Membrane Market Size to Reach US$ 7.35 billion by 2033 - Exclusive Report by DataM Intelligence
US Ophthalmology Amniotic Membrane Market - DataM Intelligence
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Key Market Drivers:
➠ Rising Burden of Eye Disorders: Increasing prevalence of conditions like dry eye disease, corneal ulcers, and keratopathy has accelerated the use of amniotic membranes in ocular surface healing.
➠ Advances in Ophthalmic Surgery: Expanding applications in corneal transplantation, pterygium excision, and refractive surgery recovery support adoption.
➠ Aging Population: The rapidly growing elderly demographic in the US fuels demand, as age-related degenerative eye diseases remain a leading cause of visual impairment.
➠ Regenerative Medicine Trends: Amniotic membranes, valued for their anti-inflammatory and healing properties, align with the broader shift toward biologics and regenerative therapies.
➠ Healthcare Access & Reimbursement: Favorable reimbursement structures in certain surgical procedures improve patient affordability and encourage wider use.
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Market Segments:
By Product Type (Cryopreserved Amniotic Membrane, Lyophilization Amniotic Membrane, Dehydrated Amniotic Membrane)
By Application (Ophthalmology, Surgical Wounds, Others)
By End-User (Hospitals, Ambulatory Surgical Centers (ASCs), Specialty Clinics, Others)
Key clinical & product developments (2024-2025)
✅ New advanced AM biomaterials for ocular/regenerative work - Celularity published (June 2025) in Regenerative Engineering & Translational Medicine on a tri-layer decellularized, dehydrated amniotic membrane (DDHAM-3L) that supports limbal stem cell proliferation (potential carrier for iPSC-derived limbal stem cells). This is an R&D / translational advance that could enable future cell-based ocular surface reconstructions.
✅ Existing commercial cryopreserved products active in 2025 clinical discussions - BioTissue's products (e.g., PROKERA, AmnioGraft / CAM360 formats, Clarix family) remain widely used and were featured in clinical/practice discussions and product literature (PROKERA still described as the FDA-cleared cryopreserved AM device in their materials). BioTissue also reported product presentations/studies in 2025.
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Mergers & acquisitions 2025
✅ New Horizon / Precise Bioscience (closed Mar 19, 2025) - New Horizon announced closing on the acquisition of Precise Bioscience, which the buyer described as a leader in advanced lyophilized amniotic membrane technologies. This is a direct example of consolidation and vertical integration in AM processing/portfolio expansion during 2025.
✅ Ongoing consolidation trend (context) - the tissue/AM space continues to consolidate (examples from prior years such as RTI Surgical's earlier activity are still relevant), and 2025 saw continued M&A and partnering activity across companies offering AM or adjacent biologic products.
Market Key Players:
Key players are MiMedx Group, Inc., Corza Ophthalmology (Katena Products, Inc.), Skye Bioscience, Inc., INTEGRA LIFESCIENCES HOLDINGS CORPORATION, Amnio Technology, LLC, Human Regenerative Technologies, LLC, Surgenex, BioTissue, VIVEX Biologics, Inc., and Merakris Therapeutics, Inc.
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