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In-Situ Hybridization Market to Grow at 11.9% CAGR, Driven by Cancer Diagnostics and Key Players Like Abbott, Roche, and Thermo Fisher

09-08-2025 02:53 PM CET | Health & Medicine

Press release from: DataM Intelligence 4Market Research LLP

In-Situ Hybridization Market

In-Situ Hybridization Market

According to DataM Intelligence,the In-Situ Hybridization (ISH) Market was valued at US$ 9700.40 million in 2022 and is projected to reach US$ 15087.46 million by 2031, growing at a CAGR of 11.9% during the forecast period 2024-2031.

The In-Situ Hybridization (ISH) Market focuses on techniques using labeled DNA, RNA, or modified nucleic acid probes to localize specific nucleic acid sequences in tissue samples, cells, or circulating tumor cells (CTCs). Unlike immunohistochemistry, which targets proteins, ISH is critical for diagnosing cancer, genetic disorders, and infectious diseases, and is used in hospitals, diagnostic laboratories, academic institutes, pharmaceutical companies, and contract research organizations (CROs).

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☛ In-Situ Hybridization (ISH) Market Forces Driving Future Growth

The ISH market is driven by the rising incidence of cancer, linked to smoking, poor diet, and lifestyle factors, with approximately 10 million cancer deaths globally in 2020, per WHO. ISH's role in diagnosing cancer subtypes, chromosomal abnormalities, and genetic diseases fuels demand. Advancements like fluorescence in situ hybridization (FISH) and new product launches, such as Vizgen's multiplexed error-resilient FISH dataset in May 2021, enhance diagnostic precision and market growth.

Challenges include a lack of trained personnel with molecular expertise, particularly in developing countries, and resistance to transitioning from manual to automated ISH processes. These factors limit widespread adoption, especially in resource-constrained settings.

Opportunities lie in expanding applications in cancer diagnostics, infectious disease detection, and neuroscience, particularly in North America, where high cancer prevalence and R&D investments drive growth. The Asia-Pacific region's rising healthcare infrastructure and genetic research also offer significant potential.

☛ In-Situ Hybridization (ISH) Industry News

Product Launches: In May 2021, Vizgen launched a public spatial genomics dataset for multiplexed error-resilient FISH, mapping 483 gene transcripts in mouse brain receptors. In March 2020, Creative Bioarray introduced an improved FISH probe for detecting 2019 novel coronavirus in infected cells.

Partnerships: In April 2021, Applied Spectral Imaging and KromaTiD partnered to distribute KromaTiD's Pinpoint FISH probes globally. In May 2020, Leica Biosystems and Bio-Techne launched the CE-IVD RNAscope ISH Detection Kit for automation on the BOND-III platform in Europe.

Market Expansion: Growing product launches and collaborations in North America strengthen the region's dominance in the ISH market.

☛ In-Situ Hybridization (ISH) Market: Industry Giants and Emerging Leaders
✦ Abbott Laboratories
✦ F. Hoffmann-La Roche AG
✦ Becton, Dickinson and Company
✦ Agilent Technologies, Inc.
✦ Thermo Fisher Scientific
✦ Bio-Rad Laboratories, Inc.
✦ Bio-Techne Corporation
✦ Creative Bioarray
✦ Biocat GmbH
✦ Zytovision

Research Methodology
Our research methodology integrates qualitative and quantitative approaches to deliver reliable market intelligence. We conduct thorough secondary research using trusted industry publications, proprietary databases, and credible market sources, complemented by primary research involving structured surveys and in-depth interviews with industry leaders, subject matter experts, and key market participants.

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☛ Segments Covered in the In-Situ Hybridization (ISH) Market

By Product
Consumables (kits, reagents, probes, accessories) dominate due to recurring use in ISH workflows. Instruments and Software support automated and precise diagnostics.

By Technology
Fluorescence In Situ Hybridization (FISH) holds the largest share due to its use in cancer diagnostics, gene mapping, and chromosomal abnormality detection. Subtypes include DNA FISH, RNA FISH, PNA FISH, alongside Chromogenic In Situ Hybridization (CISH).

By Application
Cancer Diagnostics leads due to high cancer prevalence, followed by Cytology, Infectious Disease Diagnostics, Neuroscience, and Immunology, driven by ISH's precision in detecting genetic markers.

By End User
Hospitals & Diagnostic Laboratories dominate due to widespread diagnostic services. Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, and CROs contribute through research and development.

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✔ Customized regional/country reports as per request and country-level analysis.
✔ Potential & niche segments and regions exhibiting promising growth.
✔ Top-down and bottom-up approach for regional analysis.

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☛ Regional Analysis for In-Situ Hybridization (ISH) Market
⇥ North America (U.S., Canada, Mexico) - Dominates due to high cancer rates (1.9 million new cases in 2022, per American Cancer Society), frequent product launches, and robust R&D by key players.

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands, Rest of Europe) - Growing due to advancements in automated ISH platforms and research collaborations.

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia, Rest of Asia Pacific) - Fastest-growing region, driven by rising healthcare investments and genetic research.

⇥ South America (Colombia, Brazil, Argentina, Rest of South America) - Emerging market with increasing diagnostic capabilities.

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa) - Steady growth supported by expanding healthcare infrastructure.

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About Us
DataM Intelligence is a Market Research and Consulting firm that provides end-to-end business solutions to organizations from Research to Consulting. We leverage our top trademark trends, insights, and developments to deliver swift and astute solutions to clients. Our research database features countless statistics and in-depth analyses across a wide range of 6300+ reports in 40+ domains, creating business solutions for more than 200+ companies across 50+ countries, catering to the key business research needs that influence the growth trajectory of our vast clientele.

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