Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market is expected to reach US$ 7.64 billion by 2031 | Top key players - Madrigal Pharmaceuticals, Simson Pharma Limited, Dr. Reddy's Laboratories Ltd.

Market Size and Growth:

The Global Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market size reached US$ 1.67 billion in 2023 and is expected to reach US$ 7.64 billion by 2031, growing at a CAGR of 21.8% during the forecast period 2024-2031.

Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market report, published by DataM Intelligence, provides in-depth insights and analysis on key market trends, growth opportunities, and emerging challenges. Committed to delivering actionable intelligence, DataM Intelligence empowers businesses to make informed decisions and stay ahead of the competition. Through a combination of qualitative and quantitative research methods, it offers comprehensive reports that help clients navigate complex market landscapes, drive strategic growth, and seize new opportunities in an ever-evolving global market.

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The Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market refers to the healthcare segment focused on therapies, drugs, and interventions aimed at managing and treating MASH, a progressive liver disease linked to metabolic dysfunction. The market encompasses pharmacological treatments, lifestyle interventions, and emerging therapeutic innovations designed to slow disease progression, reduce complications, and improve patient outcomes globally.

Recent Key Developments of USA and Japan:

USA:

August 15, 2025: Prime Therapeutics releases a clinical insights report highlighting the impact of Rezdiffra's FDA approval and the growing role of GLP-1s like semaglutide in treating MASH.

September 3, 2025: The FDA's Center for Drug Evaluation and Research (CDER) accepts a letter of intent to qualify Liver Stiffness Measurement by Vibration-Controlled Transient Elastography (VCTE) as a surrogate endpoint for MASH trials, potentially reducing the need for invasive liver biopsies.

Japan:

June 6, 2025: The Ministry of Health, Labour and Welfare (MHLW) and the Pharmaceuticals and Medical Devices Agency (PMDA) implement new regulatory changes to accelerate drug development and approval, aiming to reduce the country's drug lag.

March 18, 2025: The MHLW announces a six-point strategy to enhance Japan's clinical research infrastructure, focusing on improving local trial systems, using decentralized and data-driven trials, and incentivizing research participation.

Market Key Players:

Madrigal Pharmaceuticals
Simson Pharma Limited
Dr. Reddy's Laboratories Ltd.
Thermo Fisher Scientific Inc.
Biosynth
Affgility Solutions
Conscientia Industrial Co. Ltd.
Smolecule Inc.
89 Bio Inc.
Sandoo Pharmaceuticals and Chemicals Co. Ltd.

Growth Forecast Projected:

The Global Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.

Research Process:

Both primary and secondary data sources have been used in the global Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.

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Market Segmentation:

By Treatment: Drug, Therapy, Weight Management, Diabetes control, Regular Exercise, Foscarnet, Others.

By End-User: Hospitals, Specialty Clinics, Homecare, Others.

Regional Analysis:

⇥ North America (U.S., Canada, Mexico)

⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)

⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)

⇥ South America (Colombia, Brazil, Argentina, Rest of South America)

⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Benefits of the Report:

➡ A descriptive analysis of demand-supply gap, market size estimation, SWOT analysis, PESTEL Analysis and forecast in the global market.

➡ Top-down and bottom-up approach for regional analysis

➡ Porter's five forces model gives an in-depth analysis of buyers and suppliers, threats of new entrants & substitutes and competition amongst the key market players.

➡ By understanding the value chain analysis, the stakeholders can get a clear and detailed picture of this Market

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