2025 Viral Clearance Industry Trends Report: Long-Term Outlook Through 2034

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How Large Will the Viral Clearance Market Size By 2025?
In the past few years, the market size for viral clearance has seen quick expansion. From $0.82 billion in 2024, it is projected to reach $0.96 billion in 2025, with a compound annual growth rate (CAGR) of 16.9%. The surge during the historic period is mainly due to the escalation in biopharmaceutical production, enhanced regulatory focus on viral safety, increasing instances of chronic and infectious diseases, growth in manufacturing of plasma-derived products, a rise in outsourcing to Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs), and heightened usage of monoclonal antibodies and recombinant proteins.

How Big Is the Viral Clearance Market Size Expected to Grow by 2029?
Over the next several years, the viral clearance market is set for a quick expansion, with projections indicating it will increase to $1.77 billion by 2029, exhibiting a compound annual growth rate of 16.6%. The expected growth during this forecast period can be linked to the increased demand for cell and gene therapies, increased emphasis on biomanufacturing biosafety, stricter regulations on validation requirements, the growth of biologics production facilities, higher outsourcing of viral safety testing and growing use of single-use systems in bioprocessing. Key trends for the forecast period include the integration of high-throughput analytical technologies, increased adoption of single-use systems, advancements in filtration and chromatography techniques, growth in continuous bioprocessing and expansion of contract research and manufacturing services.

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Which Key Market Drivers Powering Viral Clearance Market Expansion and Growth?
The surge in chronic illnesses is set to boost the expansion of the viral clearance market in the future. Chronic illnesses are long-term health problems that develop gradually and can last for several months or years, often necessitating continuous treatment or management. The global increase in chronic diseases, predominantly due to an aging population and improved living standards, results in an upswing in age-related conditions such as heart disease, diabetes, cancer, and arthritis. Viral clearance, which is pivotal in the production of biologics and gene therapies for chronic illness treatment, guarantees their safety and effectiveness. For example, the Institute for Health Metrics and Evaluation, a U.S-based public health research centre, stated in June 2023, that over half a billion people around the world were affected by diabetes. This number is anticipated to more than double, hitting 1.3 billion individuals by 2050. Hence, the growing prevalence of chronic illnesses is spearheading the expansion of the viral clearance market.

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What Trends Will Shape the Viral Clearance Market Through 2029 and Beyond?
In the viral clearance market, leading companies are centering their efforts around enhancing their ability to expand, specifically through the development of large-scale viral vector manufacturing facilities. These facilities cater to the increasing demand for gene therapies and biologics. Such facilities are essentially advanced bioproduction sites equipped with specialized facilities aimed at producing viral vectors, which are used in cell and gene therapy. Their purpose is to maintain high purity, safety, and observance of viral clearance regulations. In August 2022, for example, Thermo Fisher Scientific, a biotech company based in the United States, unveiled its new commercial viral vector manufacturing facility, boasting 300,000 square feet, in Plainville, Massachusetts. This new addition has doubled its global capacity and allows for comprehensive manufacturing, including viral clearance and analytical testing. This prepares the way for the fast, secure commercial introduction of gene therapies, vaccines, and advanced biologics.

What Are the Emerging Segments in the Viral Clearance Market?
The viral clearance market covered in this report is segmented

1) By Method: Viral Clearance Method, Viral Removal Method, Viral Inactivation Method, Viral Detection Method
2) By Application: Vaccines And Therapeutics, Blood And Blood Products, Cellular And Gene Therapy Products, Tissue And Tissue Products, Other Applications
3) By End-User: Pharmaceutical And Biotechnology Companies, Contract Research Organizations, Academic Research Institutes, Other End Users

Subsegments:
1) By Viral Clearance Method: Downstream Processing, Filtration, Chromatography, Precipitation, Nanofiltration
2) By Viral Removal Method: Membrane Chromatography, Depth Filtration, Nanofiltration, Ultrafiltration, Protein A Affinity Chromatography
3) By Viral Inactivation Method: Solvent Detergent Method, Low pH Treatment, Heat Treatment (Pasteurization), UV-C Irradiation, Caprylate Treatment
4) By Viral Detection Method: PCR (Polymerase Chain Reaction), ELISA (Enzyme-Linked Immunosorbent Assay), Nucleic Acid Testing (NAT), Cell-Based Assays, Transmission Electron Microscopy (TEM)

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Who Are the Global Leaders in the Viral Clearance Market?
Major companies operating in the viral clearance market are F Hoffmann-La Roche Ltd., Merck Group, Thermo Fisher Scientific Inc., Asahi Kasei Corporation, SGS SA, Eurofins Scientific Inc., Lonza Group AG, WuXi AppTec, Catalent Biologics, Charles River Laboratories, Kedrion Biopharma, Nelson Labs, Pall Corporation, Sartorius AG, Syngene International, Microbac Laboratories, Creative Biolabs, Texcell SA, GTP Bioways, and Vironova AB.

Which are the Top Profitable Regional Markets for the Viral Clearance Industry?
North America was the largest region in the viral clearance market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the viral clearance market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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