openPR Logo
Press release

Atypical Hemolytic Uremic Syndrome Pipeline 2025: Detailed Clinical Trials and FDA-Approved Therapies Review by DelveInsight | Alexion Pharmaceuticals, Hoffmann-La Roche, Novartis, NovelMed Thera

09-03-2025 04:48 PM CET | Business, Economy, Finances, Banking & Insurance

Press release from: ABNewswire

Atypical Hemolytic Uremic Syndrome Pipeline 2025: Detailed

Las Vega (Nevada), United States //- As per DelveInsight's assessment, globally, Atypical Hemolytic Uremic Syndrome pipeline constitutes 5+ key companies continuously working towards developing 5+ Atypical Hemolytic Uremic Syndrome treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Atypical Hemolytic Uremic Syndrome Pipeline Insight, 2025 [https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Atypical Hemolytic Uremic Syndrome Market.

The Atypical Hemolytic Uremic Syndrome Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the Atypical Hemolytic Uremic Syndrome Pipeline Report:

*
Companies across the globe are diligently working toward developing novel Atypical Hemolytic Uremic Syndrome treatment therapies with a considerable amount of success over the years. Atypical Hemolytic Uremic Syndrome Key players such as - Alexion Pharmaceuticals, Hoffmann-La Roche, Novartis, NovelMed Therapeutics, and others, are developing therapies for the Atypical Hemolytic Uremic Syndrome treatment

*
Atypical Hemolytic Uremic Syndrome Emerging therapies such as - Eculizumab, Crovalimab, Iptacopan, NM8074, Ravulizumab, and others are expected to have a significant impact on the Atypical Hemolytic Uremic Syndrome market in the coming years.

*
In June 2025, Novartis reported positive findings from APPULSE-PNH, a Phase IIIB trial assessing the efficacy and safety of twice-daily oral monotherapy Fabhalta Registered (iptacopan) in adults with paroxysmal nocturnal hemoglobinuria (PNH) who had hemoglobin levels greater than or equal to 10 g/dL and transitioned from anti-C5 therapies (eculizumab or ravulizumab). After 24 weeks, Fabhalta treatment led to an average hemoglobin increase of 2.01 g/dL (95% CI, 1.74-2.29), with most patients reaching normal or near-normal levels. These results will be shared at the European Hematology Association (EHA) Congress 2025. Beyond PNH, Fabhalta is being investigated in several rare kidney disorders, including atypical hemolytic uremic syndrome (aHUS), immune complex membranoproliferative glomerulonephritis (IC-MPGN), and lupus nephritis (LN), with ongoing studies evaluating safety, efficacy, and potential for regulatory approvals.

*
In April 2025, Teva Pharmaceuticals, the U.S. affiliate of Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA), along with Samsung Bioepis Co., Ltd., announced the U.S. launch of EPYSQLI Registered (eculizumab-aagh). EPYSQLI, a biosimilar to Soliris Registered (eculizumab), is approved for treating paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AchR) antibody positive. Priced at a 30% lower Wholesale Acquisition Cost (WAC) than Soliris Registered , EPYSQLI represents one of the most cost-effective biosimilar alternatives to Soliris Registered in the U.S.

Atypical Hemolytic Uremic Syndrome Overview

Atypical Hemolytic Uremic Syndrome (aHUS) is a rare, life-threatening disease characterized by the abnormal activation of the complement system, part of the immune system. This leads to the destruction of red blood cells (hemolysis), low platelet counts (thrombocytopenia), and damage to small blood vessels, particularly in the kidneys, causing kidney failure. Unlike typical HUS, which is often triggered by infections such as E. coli, aHUS is usually caused by genetic mutations or autoimmune factors affecting complement regulation. Early diagnosis and targeted therapies, such as complement inhibitors, are crucial to prevent organ damage and improve outcomes.

Get a Free Sample PDF Report to know more about Atypical Hemolytic Uremic Syndrome Pipeline Therapeutic Assessment-

https://www.delveinsight.com/report-store/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight [https://www.delveinsight.com/report-store/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Emerging Atypical Hemolytic Uremic Syndrome Drugs Under Different Phases of Clinical Development Include:

*
Eculizumab: Alexion Pharmaceuticals

*
Crovalimab: Hoffmann-La Roche

*
Iptacopan: Novartis

*
NM8074: NovelMed Therapeutics

*
Ravulizumab: Alexion Pharmaceuticals

Route of Administration

Atypical Hemolytic Uremic Syndrome pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as

*
Oral

*
Parenteral

*
Intravenous

*
Subcutaneous

*
Topical

Molecule Type

Products have been categorized under various Molecule types, such as

*
Monoclonal Antibody

*
Peptides

*
Polymer

*
Small molecule

*
Gene therapy

Atypical Hemolytic Uremic Syndrome Pipeline Therapeutics Assessment

*
Atypical Hemolytic Uremic Syndrome Assessment by Product Type

*
Atypical Hemolytic Uremic Syndrome By Stage and Product Type

*
Atypical Hemolytic Uremic Syndrome Assessment by Route of Administration

*
Atypical Hemolytic Uremic Syndrome By Stage and Route of Administration

*
Atypical Hemolytic Uremic Syndrome Assessment by Molecule Type

*
Atypical Hemolytic Uremic Syndrome by Stage and Molecule Type

DelveInsight's Atypical Hemolytic Uremic Syndrome Report covers around 5+ products under different phases of clinical development like

*
Late-stage products (Phase III)

*
Mid-stage products (Phase II)

*
Early-stage product (Phase I)

*
Pre-clinical and Discovery stage candidates

*
Discontinued & Inactive candidates

*
Route of Administration

Some of the key companies in the Atypical Hemolytic Uremic Syndrome Therapeutics Market include:

Key companies developing therapies for Atypical Hemolytic Uremic Syndrome treatment are - Alexion Pharmaceuticals (a subsidiary of AstraZeneca), Apellis Pharmaceuticals, Novartis, Achillion Pharmaceuticals (a subsidiary of Alexion Pharmaceuticals), Omeros Corporation, Ra Pharmaceuticals (now part of UCB), Regeneron Pharmaceuticals, Chugai Pharmaceutical, and others.

Download Sample PDF Report to know more about Atypical Hemolytic Uremic Syndrome drugs and therapies [https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Atypical Hemolytic Uremic Syndrome Pipeline Analysis:

The Atypical Hemolytic Uremic Syndrome pipeline report provides insights into

*
The report provides detailed insights about companies that are developing therapies for the treatment of Atypical Hemolytic Uremic Syndrome with aggregate therapies developed by each company for the same.

*
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Atypical Hemolytic Uremic Syndrome Treatment.

*
Atypical Hemolytic Uremic Syndrome key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

*
Atypical Hemolytic Uremic Syndrome Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

*
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Atypical Hemolytic Uremic Syndrome market.

The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Further Atypical Hemolytic Uremic Syndrome product details are provided in the report. Download the Atypical Hemolytic Uremic Syndrome pipeline report to learn more about the emerging Atypical Hemolytic Uremic Syndrome therapies [https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Atypical Hemolytic Uremic Syndrome Pipeline Market Drivers

*
Increasing prevalence due to improved survival

*
Rising awareness of aHUS

*
Good emerging pipeline assets driving the R&D

*
Changing scenario in treatment landscape

Atypical Hemolytic Uremic Syndrome Pipeline Market Barriers

*
Lack of definite diagnosis criteria

*
Upcoming biosimilars in the market

*
Challenges in clinical trials

*
Premium pricing of the drugs has resulted in low commercial uptake

Scope of Atypical Hemolytic Uremic Syndrome Pipeline Drug Insight

*
Coverage: Global

*
Key Atypical Hemolytic Uremic Syndrome Companies: Alexion Pharmaceuticals, Hoffmann-La Roche, Novartis, NovelMed Therapeutics, and others

*
Key Atypical Hemolytic Uremic Syndrome Therapies: Eculizumab, Crovalimab, Iptacopan, NM8074, Ravulizumab, and others

*
Atypical Hemolytic Uremic Syndrome Therapeutic Assessment: Atypical Hemolytic Uremic Syndrome current marketed and Atypical Hemolytic Uremic Syndrome emerging therapies

*
Atypical Hemolytic Uremic Syndrome Market Dynamics: Atypical Hemolytic Uremic Syndrome market drivers and Atypical Hemolytic Uremic Syndrome market barriers

Request for Sample PDF Report for Atypical Hemolytic Uremic Syndrome Pipeline Assessment and clinical trials [https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=gpr]

Table of Contents

1

Atypical Hemolytic Uremic Syndrome Report Introduction

2

Atypical Hemolytic Uremic Syndrome Executive Summary

3

Atypical Hemolytic Uremic Syndrome Overview

4

Atypical Hemolytic Uremic Syndrome- Analytical Perspective In-depth Commercial Assessment

5

Atypical Hemolytic Uremic Syndrome Pipeline Therapeutics

6

Atypical Hemolytic Uremic Syndrome Late Stage Products (Phase II/III)

7

Atypical Hemolytic Uremic Syndrome Mid Stage Products (Phase II)

8

Atypical Hemolytic Uremic Syndrome Early Stage Products (Phase I)

9

Atypical Hemolytic Uremic Syndrome Preclinical Stage Products

10

Atypical Hemolytic Uremic Syndrome Therapeutics Assessment

11

Atypical Hemolytic Uremic Syndrome Inactive Products

12

Company-University Collaborations (Licensing/Partnering) Analysis

13

Atypical Hemolytic Uremic Syndrome Key Companies

14

Atypical Hemolytic Uremic Syndrome Key Products

15

Atypical Hemolytic Uremic Syndrome Unmet Needs

16

Atypical Hemolytic Uremic Syndrome Market Drivers and Barriers

17

Atypical Hemolytic Uremic Syndrome Future Perspectives and Conclusion

18

Atypical Hemolytic Uremic Syndrome Analyst Views

19

Appendix

20

About DelveInsight

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

Media Contact
Company Name: DelveInsight
Contact Person: Gaurav Bora
Email:Send Email [https://www.abnewswire.com/email_contact_us.php?pr=atypical-hemolytic-uremic-syndrome-pipeline-2025-detailed-clinical-trials-and-fdaapproved-therapies-review-by-delveinsight-alexion-pharmaceuticals-hoffmannla-roche-novartis-novelmed-thera]
Phone: +14699457679
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/

Legal Disclaimer: Information contained on this page is provided by an independent third-party content provider. ABNewswire makes no warranties or responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you are affiliated with this article or have any complaints or copyright issues related to this article and would like it to be removed, please contact retract@swscontact.com



This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Atypical Hemolytic Uremic Syndrome Pipeline 2025: Detailed Clinical Trials and FDA-Approved Therapies Review by DelveInsight | Alexion Pharmaceuticals, Hoffmann-La Roche, Novartis, NovelMed Thera here

News-ID: 4168682 • Views:

More Releases from ABNewswire

Active Acres Sells 5.30-Acre Corner Lot in Madison, Georgia, Above Expectations
Active Acres Sells 5.30-Acre Corner Lot in Madison, Georgia, Above Expectations
In Morgan County, Georgia, just minutes from the historic streets of Madison, a 5.30-acre corner lot recently sold - proof of the strong demand for well-prepared, scenic acreage in desirable locations. With dual road frontage, natural beauty, and full build-readiness, the parcel stood out to buyers and was quickly secured. A Property Positioned for Success Located at the intersection of Enterprise Road and Paschal Road, the property offered unmatched accessibility with 800
Two Canadians Just Reinvented the Hand Warmer With a Bright Yellow Pouch Called PREFIRE.
10-02-2025 | Sports
ABNewswire
Two Canadians Just Reinvented the Hand Warmer With a Bright Yellow Pouch Called …
TORONTO, ON - Oct 2, 2025 - Hand warmers haven't changed in decades - until now. Toronto entrepreneurs Scott Boniface and Ryan Bannon have launched PREFIRE, a bright yellow pouch that delivers 8+ hours of steady heat while doubling as a modern ritual of calm, clarity, and comfort. Image: https://www.abnewswire.com/upload/2025/10/64380d60e491816c1b20d5fdd685cc4f.jpg More than warmth, PREFIRE is designed to help people pause. Each compostable pouch generates reliable heat that keeps hands warm, but the
Frankfurt Black Limo Launches First Class Limo Service 24/7 in Frankfurt
Frankfurt Black Limo Launches First Class Limo Service 24/7 in Frankfurt
FRANKFURT, GERMANY - October 2, 2025 - Frankfurt Black Limo has set a new benchmark for luxury in the city by proudly announcing the launch of its first-class limo service that is now available 24/7 in Frankfurt. This new service is designed to meet the growing need of business leaders and VIPs for 24-hour chauffeur service in a city that serves as both financial and cultural hub of Europe. Their 24/7
Quantum AI Expands Global Presence with Breakthroughs in Trading Technology
Quantum AI Expands Global Presence with Breakthroughs in Trading Technology
LUTON, United Kingdom - October 10, 2025 - Quantum AI, a leading innovator in artificial intelligence enhanced by quantum computing, today announced continued advancements in its technology platform and expansion of its global presence. The company's work is centered on creating practical applications for financial markets and beyond, leveraging the power of quantum mechanics to refine complex data analysis. Quantum AI operates from its UK office at 35 John Street, Luton,

All 5 Releases


More Releases for Atypical

Atypical Teratoid Rhabdoid Tumors (ATRT) Market reaching approximately USD 1.7 b …
Atypical Teratoid Rhabdoid Tumor (ATRT) is a rare and aggressive brain tumor primarily affecting children, although it can occasionally occur in adults. ATRT is characterized by the rapid growth of undifferentiated cells, typically located in the central nervous system, including the brain and spinal cord. Due to its rarity, the diagnosis and management of ATRT remain challenging. While treatment often includes a combination of surgery, radiation, and chemotherapy, outcomes for
Atypical Hemolytic Uremic Syndrome Market Innovations, Key Players, and Growth O …
Atypical Hemolytic Uremic Syndrome (aHUS) is a rare and life-threatening condition characterized by hemolytic anemia, thrombocytopenia, and acute kidney failure. Unlike the more common typical HUS, which is typically caused by bacterial infections (e.g., E. coli), aHUS results from complement system dysfunction-the body's immune defense mechanism that, when overactive, leads to endothelial damage, microvascular thrombosis, and organ damage, primarily affecting the kidneys. Download Full PDF Sample Copy of Market Report @
Atypical Teratoid Rhabdoid Tumors Pipeline Outlook, FDA Approvals, Clinical Tria …
DelveInsight's, "Atypical Teratoid Rhabdoid Tumors Pipeline Insight 2024" report provides comprehensive insights about 6+ companies and 6+ pipeline drugs in Atypical Teratoid Rhabdoid Tumors (ATRT) pipeline landscape. It covers the Atypical Teratoid Rhabdoid Tumors pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Atypical Teratoid Rhabdoid Tumors therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products
Atypical Antipsychotic Drugs Market Size, Share, Emerging Trends, Analysis and F …
The latest Antipsychotic Drugs Market study offers an all-inclusive analysis of the major strategies, corporate models, and market shares of the most noticeable players in this market. The study offers a thoroughanalysis of the key persuading factors, market figures in terms of revenues, segmental data, regional data, and country-wise data. This study can be described as most wide-ranging documentation that comprises all the aspects of the evolving Antipsychotic Drugs Market. Psychosis
Atypical Chemokine Receptor 3 Market Report Includes Dynamics, Products, and App …
A consistent market research report like Atypical Chemokine Receptor 3 Market report extends reach to the success in the business. All the data and statistic included in the report is backed up by well-known analysis tools which include SWOT analysis and Porter’s Five Forces analysis. Market research studies carried out in this report are very considerate which assist businesses to take better decisions and develop superior strategies about production, marketing,
Atypical Antipsychotic Drugs Market Size, Share, Development by 2025
Market Research Report Store offers a latest published report on Atypical Antipsychotic Drugs Market Analysis and Forecast 2019-2025 delivering key insights and providing a competitive advantage to clients through a detailed report. Atypical antipsychotic drugs are a type of antipsychotic drugs used in treatment of psychosis. They do not cure psychosis but help in controlling symptoms such as hallucinations, and delusions, among others. The global Atypical Antipsychotic Drugs market is valued at