Chronic Plaque Psoriasis Market to Reach USD 44 Billion by 2034

Chronic plaque psoriasis is the most common form of psoriasis, accounting for nearly 80-90% of all cases. It is a chronic, immune-mediated skin disorder characterized by red, scaly plaques that can significantly affect physical and psychological well-being. The disease is linked to genetic, immune, and environmental factors, and often coexists with conditions such as psoriatic arthritis, cardiovascular disease, and metabolic syndrome.

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The global chronic plaque psoriasis market is undergoing a major transformation with the advent of biologics, small-molecule targeted therapies, and precision medicine approaches. Increased awareness, supportive reimbursement frameworks, and rising prevalence of autoimmune diseases are fueling strong growth through 2034.

Market Overview
• Market Size 2024: USD 25 billion
• Forecast 2034: USD 44 billion
• CAGR (2025-2034): 6%

The chronic plaque psoriasis market is projected to expand at a robust CAGR, driven by rising adoption of biologics, expanding biosimilar portfolios, and innovation in oral small molecules such as JAK inhibitors and TYK2 inhibitors. Patient demand for effective and long-term solutions is also boosting uptake.

Leading Players include: Novartis, AbbVie, Eli Lilly, Johnson & Johnson, Amgen, Bristol Myers Squibb, Pfizer, UCB, and emerging biotech firms focusing on dermatology.

Segmentation Analysis
By Product
• Biologics (TNF inhibitors, IL-17 inhibitors, IL-23 inhibitors, IL-12/23 inhibitors)
• Small-Molecule Targeted Therapies (JAK inhibitors, TYK2 inhibitors)
• Conventional Systemics (methotrexate, cyclosporine, acitretin)
• Topical Agents (corticosteroids, vitamin D analogs, calcineurin inhibitors)
• Biosimilars
• Supportive Care Medications

By Platform
• Hospital Pharmacies
• Specialty Pharmacies
• Online Pharmacies

By Technology
• Biologic & Biosimilar Drug Development
• Small Molecule Innovation Platforms
• Precision Medicine & Biomarker Testing
• Digital & AI-Based Dermatology Tools

By End Use
• Hospitals & Dermatology Clinics
• Specialty Immunology Centers
• Academic & Research Institutes
• Homecare Settings

By Application
• Mild to Moderate Plaque Psoriasis
• Moderate to Severe Plaque Psoriasis

Summary:
Biologics dominate the market, particularly IL-17 and IL-23 inhibitors, due to their efficacy and durability. Small-molecule therapies such as JAK and TYK2 inhibitors are emerging as attractive oral alternatives. Biosimilars are expanding affordability and access globally.

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Regional Analysis
North America
• Largest market, driven by high prevalence, FDA approvals of biologics and oral therapies, and strong reimbursement support.
• U.S. dominates with rapid adoption of IL-23 inhibitors and TYK2 inhibitors.
Europe
• Strong presence supported by EMA approvals, universal healthcare systems, and widespread biosimilar adoption.
• Germany, France, and the UK lead in advanced therapy uptake.
Asia-Pacific
• Fastest-growing region with rising prevalence of autoimmune disorders, improving access to biologics, and expanding biosimilar markets in China, India, and Japan.
Middle East & Africa
• Gradual growth as dermatology infrastructure expands, though access to biologics remains limited.
Latin America
• Moderate growth, with Brazil and Mexico leading adoption of biologics and biosimilars.
Regional Summary:
While North America and Europe dominate in adoption, Asia-Pacific is expected to record the fastest CAGR through 2034, driven by rising awareness, healthcare investments, and biosimilar launches.

Market Dynamics
Key Growth Drivers
• Rising prevalence of chronic plaque psoriasis globally.
• Expanding adoption of biologics and targeted oral therapies.
• Growing biosimilar availability lowering treatment costs.
• Advances in precision medicine and biomarker-driven care.

Key Challenges
• High costs of biologics and novel oral therapies.
• Limited awareness and access in low-income regions.
• Risk of adverse effects and loss of response to biologics.

Latest Trends
• FDA/EMA approvals of TYK2 inhibitors (e.g., deucravacitinib).
• Expansion of IL-23 inhibitors as long-term therapy.
• Growth of digital health platforms for psoriasis management.
• Increasing focus on combination regimens for better efficacy.

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Competitor Analysis
Major Players in the Market:
• Novartis - Strong with Cosentyx (IL-17 inhibitor).
• AbbVie - Market leader with Humira and Skyrizi (IL-23 inhibitor).
• Eli Lilly - Leading with Taltz (IL-17 inhibitor).
• Johnson & Johnson - Strong portfolio with Stelara (IL-12/23 inhibitor) and Tremfya (IL-23 inhibitor).
• Amgen - Focused on biologics and biosimilar launches.
• Bristol Myers Squibb - Innovator with TYK2 inhibitor deucravacitinib.
• Pfizer - Expanding JAK inhibitor pipeline.
• UCB - Key dermatology-focused biologic portfolio.

Competitive Dynamics:
The market is competitive and innovation-driven, with AbbVie, Novartis, and Eli Lilly dominating biologics, while BMS and Pfizer are pushing oral small molecules. Biosimilar adoption is further intensifying competition.

Conclusion
The chronic plaque psoriasis market is evolving rapidly with the rise of biologics, oral targeted therapies, and biosimilars. While affordability and access remain challenges, the strong pipeline and adoption of precision medicine ensure robust growth through 2034.

Key Takeaways:
• Market projected to grow at a CAGR of 6.0% (2025-2034).
• IL-17 and IL-23 inhibitors dominate, while TYK2 and JAK inhibitors are the fastest-growing therapies.
• North America and Europe lead adoption, while Asia-Pacific posts strongest growth.
• Biosimilars and digital health platforms are expanding accessibility.
• Competition is driven by pipeline innovation, biosimilar expansion, and precision medicine approaches.

Overall, the chronic plaque psoriasis market presents strong opportunities for global pharma leaders, biotech innovators, and healthcare providers, with next-generation therapies paving the way for long-term disease control and improved patient quality of life.

This report is also available in the following languages : Japanese (慢性プラーク乾癬市場), Korean (만성 플라크 건선 시장), Chinese (慢性斑块型银屑病市场), French (Marché du psoriasis en plaques chronique), German (Markt für chronische Plaque-Psoriasis), and Italian (Mercato della psoriasi a placche cronica), etc.

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