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Protein Therapeutics Market to Hit USD 558.95 Billion by 2032 Amid Rising Chronic Disease Burden | Coherent Market Insights
Protein Therapeutics Market
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Global Protein Therapeutics Market Key Takeaways
According to Coherent Market Insights (CMI), the global protein therapeutics market size is projected to expand at a CAGR of 7.1% during the assessment period, reaching USD 558.95 Bn by 2032, up from USD 345.82 Bn in 2025.
Monoclonal antibodies (mAbs) are expected to remain highly sought-after products, accounting for more than two-fifths of the global protein therapeutics market share in 2025.
Cancer treatment, with an estimated market share of 28.2% in 2025, is projected to be the most lucrative application of protein therapeutics.
Recombinant DNA technology is posed to dominate the industry, capturing a 38.3% global market share by 2025.
North America remains the undisputed market leader, accounting for nearly two-fifths of the global protein therapeutics industry share in 2025.
Asia Pacific is expected to emerge as a hotbed for protein therapeutics companies during the forecast period.
Rising Prevalence of Chronic Diseases Fueling Market Growth
Coherent Market Insights' latest protein therapeutics market analysis highlights key factors driving industry expansion. Rising incidence of chronic diseases is one such prominent growth driver.
The global burden of chronic conditions like cancer, diabetes, autoimmune disorders, and cardiovascular diseases continues to rise. For instance, the International Agency for Research on Cancer (IARC) projects that annual new cancer cases will surpass 35 million by 2050.
This growing incidence of chronic diseases is expected to drive demand for protein therapeutics such as monoclonal antibodies and insulin analogs. These biological medicines offer targeted and effective treatment options for chronic and infectious diseases.
High Cost Limiting Protein Therapeutics Market Growth
The global protein therapeutics market outlook looks positive, owing to increasing demand for protein-based therapies. However, high cost of protein therapies remains a significant barrier to broader market growth.
Protein-based medicines are quite expensive as they need advanced biotechnological processes like fermentation and purification. This limits their adoption, especially across low- and middle-income regions, dampening protein therapeutics market demand.
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Biotech Advancements Creating Growth Avenues
Breakthroughs in biotechnology, especially the creation of monoclonal antibodies, are enhancing the specificity and efficacy of treatments. These innovations are transforming how diseases are managed by offering targeted therapies for conditions that were previously difficult to treat. Such innovations are anticipated to create lucrative growth opportunities in the protein therapeutics industry.
Impact of AI on the Protein Therapeutics Market
Artificial intelligence (AI) is turning out to be a powerful tool in the protein therapeutics market. It has the tendency to accelerate drug discovery as well as optimize protein design and enhance precision in treatment development.
AI-driven tools enable researchers to predict protein structures, identify potential therapeutic targets, and streamline clinical trial processes. By doing so, they significantly reduce time and costs.
AI also enables personalized medicine by examining large datasets to customize protein-based therapies for each patient. This approach enhances both treatment effectiveness and safety.
Players like Grifols lead from the forefront when it comes to employing AI-powered tools in protein therapeutic production. For instance, Grifols recently teamed up with Google Cloud to use advanced technologies like AI to accelerate the development of innovative biopharma medicines.
Emerging Protein Therapeutics Market Trends
Rising demand for monoclonal antibodies is a key trend in the protein therapeutics market. These antibodies are in high demand due to rising usage in oncology, immunology, and infectious diseases. Ongoing advancements in antibody engineering, such as the creation of bispecific antibodies and antibody-drug conjugates (ADCs) are expected to expand their therapeutic potential.
Advances in protein engineering like recombinant technology, CRISPR, and ADCs are enhancing specificity, stability, and treatment outcomes. These innovations will likely provide a strong impetus for the expansion of protein therapeutics industry.
Rise of biosimilars due to patent expirations is expected to improve the protein therapeutics market value during the forecast period. They are making protein therapeutics more accessible and cost-effective for patients.
Growing popularity of personalized medicine is creating revenue streams for protein therapeutic manufacturers. Protein therapeutics enable companies to create customized treatments based on individual genetic and molecular profiles.
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Analyst's View
"The global protein therapeutics industry is set to grow steadily, owing to increasing prevalence of chronic diseases, rising popularity of protein-based therapies like monoclonal antibodies, and advancements in biotechnology," said a senior CMI analyst.
Current Events and Their Impact on the Protein Therapeutics Market
Event
Description and Impact
European Union Regulatory Harmonization and Market Access Initiatives
* Description: In January 2025, the European Union Health Technology Assessment (HTA) Regulation came into effect, aiming to streamline the evaluation process for health technologies across member states EMA.
* Impact: This is expected to improve the availability of protein-based therapies in European nations.
AI-Driven Protein Therapeutics
* Description: Technologies like DeepMind's AlphaFold 4 are enhancing protein structure prediction accuracy.
* Impact: These innovations reduce protein drug development timelines and costs.
Breakthrough Therapy Designations and Accelerated Approval Trends
* Description: FDA has expanded use of real-world evidence for biologics.
* Impact: This reduces clinical trial requirements as well as accelerates market entry for protein therapeutics.
Competitor Insights
Key companies in protein therapeutics market report:
- Thermo Fisher Scientific Inc.
- Amgen Inc.
- Genentech (Roche)
- AbbVie Inc.
- Merck and Co.
- Novo Nordisk
- Biogen Inc.
- Johnson and Johnson
- Pfizer Inc.
- Eli Lilly and Company
- AstraZeneca
- Bristol-Myers Squibb
- Gilead Sciences
- Regeneron Pharmaceuticals
- Aurigene Pharmaceutical Services Ltd.
Key Developments
In June 2025, the U.S. Food and Drug Administration (FDA) approved Merck's ENFLONSIA for preventing RSV lower respiratory tract disease in infants born during or entering their first RSV season. It is a long-acting monoclonal antibody (mAb) that provides rapid and durable protection for up to five months.
In December 2024, Grifols shared the main results of its Phase 3 PRECIOSA study, which tested the long-term use of Albutein treatment in people with severe liver disease (decompensated cirrhosis) and fluid buildup in the abdomen (ascites).
Market Segmentation
Product Type Insights (Revenue, USD Bn, 2020 - 2032)
Monoclonal Antibodies (mAbs)
Insulin and Analogues
Recombinant Proteins
Fusion Proteins
Blood Factors
Human Growth Hormones (hGH)
Follicle-Stimulating Hormone (FSH)
Interferons
Others (e.g., Erythropoietin, etc.)
Application Insights (Revenue, USD Bn, 2020 - 2032)
Cancer Treatment
Autoimmune Diseases
Infectious Diseases
Hemophilia and Coagulation Disorders
Diabetes
Cardiovascular Diseases
Neurological Disorders
Genetic Disorders
Technology Insights (Revenue, USD Bn, 2020 - 2032)
Recombinant DNA Technology
Cell-Based Technology
Hybridoma Technology
Others (Gene Editing, Transfection)
Route of Administration Insights (Revenue, USD Bn, 2020 - 2032)
Parenteral (Injectables)
Oral
Others (Topical, Nasal)
End User Insights (Revenue, USD Bn, 2020 - 2032)
Hospitals
Clinics
Research Laboratories
Pharmaceutical and Biotechnology Companies
Regional Insights (Revenue, USD Bn, 2020 - 2032)
North America
U.S.
Canada
Latin America
Brazil
Argentina
Mexico
Rest of Latin America
Europe
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Middle East
GCC Countries
Israel
Rest of Middle East
Africa
South Africa
North Africa
Central Africa
About Us:
Coherent Market Insights leads into data and analytics, audience measurement, consumer behaviors, and market trend analysis. From shorter dispatch to in-depth insights, CMI has exceled in offering research, analytics, and consumer-focused shifts for nearly a decade. With cutting-edge syndicated tools and custom-made research services, we empower businesses to move in the direction of growth. We are multifunctional in our work scope and have 450+ seasoned consultants, analysts, and researchers across 26+ industries spread out in 32+ countries.
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