Press release
Gastroenteropancreatic Neuroendocrine Tumors Market Set to Double to USD 7.8 Billion by 2034
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of rare malignancies that arise from hormone-producing neuroendocrine cells within the gastrointestinal tract and pancreas. Though uncommon compared to other cancers, their prevalence is increasing due to improved diagnostic imaging, endoscopic screening, and heightened clinical awareness.Download Full PDF Sample Copy of Market Report @ https://exactitudeconsultancy.com/request-sample/71171
GEP-NETs can range from indolent tumors to aggressive malignancies, making management highly complex. Treatment options include somatostatin analogs (SSAs), targeted therapies, peptide receptor radionuclide therapy (PRRT), chemotherapy, and surgery. The growing patient pool, coupled with pharmaceutical and biotech innovation, positions the GEP-NET market for robust growth in the next decade.
Market Overview
• Market Size (2024): USD 3.9 billion
• Forecast (2034): USD 7.8 billion
• CAGR (2025-2034): 7.2%
The GEP-NET market is expanding steadily due to rising diagnosis rates, strong adoption of targeted therapies, and government incentives for rare disease drug development.
Key Highlights:
• Increasing incidence and earlier detection of GEP-NETs worldwide.
• Somatostatin analogs remain standard-of-care, while PRRT and targeted therapies are expanding.
• Orphan drug incentives driving pharma and biotech investments.
• Growing focus on personalized oncology and biomarker-based therapies.
Segmentation Analysis
By Product Type:
• Somatostatin Analogs (Octreotide, Lanreotide, Pasireotide)
• Targeted Therapies (Everolimus, Sunitinib)
• Chemotherapy Agents
• Radiotherapy & PRRT (Lutetium-177 DOTATATE)
• Immunotherapies (emerging pipeline)
By Platform:
• Small Molecules
• Biologics
• Combination Therapies
By Technology:
• Imaging (CT, MRI, PET-CT)
• Endoscopy & Biopsy Tools
• Nuclear Medicine (PRRT)
• Immuno-oncology Research
By End Use:
• Hospitals
• Specialty Oncology Clinics
• Research Institutes
By Application:
• Gastric NETs
• Small Intestinal NETs
• Pancreatic NETs (pNETs)
• Colorectal NETs
• Others (appendiceal, duodenal NETs)
Segmentation Summary:
Somatostatin analogs dominate first-line treatment, while PRRT and targeted therapies are emerging as key options for advanced disease. Pancreatic NETs represent one of the largest and fastest-growing application areas.
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Regional Analysis
North America
• Largest market with ~44% share in 2024.
• Strong adoption of SSAs, targeted therapies, and PRRT.
• High clinical trial activity in the U.S. driving innovation.
Europe
• Accounts for ~30% share.
• Germany, UK, and France lead in adoption of nuclear medicine and PRRT.
• Strong orphan drug designation policies supporting pipeline expansion.
Asia-Pacific
• Fastest-growing region with CAGR of ~8.4%.
• Rising incidence in China, Japan, and India.
• Expanding oncology infrastructure and access to advanced therapies.
Middle East & Africa
• Limited adoption due to cost and availability barriers.
• Gradual growth with specialty cancer centers in urban hubs.
Latin America
• Brazil and Mexico driving regional demand.
• Growing adoption of SSAs and targeted drugs with better healthcare access.
Regional Summary:
North America and Europe dominate due to advanced cancer care ecosystems and strong research activity, while Asia-Pacific is expected to show the fastest growth due to its expanding patient pool and healthcare infrastructure.
Market Dynamics
Key Growth Drivers:
• Rising global incidence of rare cancers, including GEP-NETs.
• Increasing adoption of PRRT and targeted therapies.
• Expansion of orphan drug policies and rare cancer funding.
• Advances in imaging and nuclear medicine for early detection.
Key Challenges:
• High treatment costs, particularly for PRRT and biologics.
• Small patient population limiting R&D scale.
• Delayed diagnosis in emerging economies due to lack of awareness.
• Reimbursement barriers in low- and middle-income countries.
Latest Trends:
• Expansion of PRRT as a frontline treatment for advanced GEP-NETs.
• Integration of immunotherapy into treatment regimens.
• AI-driven diagnostics for early detection and treatment optimization.
• Partnerships between pharma, biotech, and academic research centers.
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Competitor Analysis
Major Players in the Market:
• Novartis AG (Sandostatin, Lutathera)
• Ipsen (Somatuline Depot)
• Pfizer Inc.
• Roche Holding AG
• Bristol Myers Squibb (BMS)
• Eli Lilly and Company
• Merck & Co., Inc.
• Amgen Inc.
• Advanced Accelerator Applications (AAA - Novartis subsidiary)
• Teva Pharmaceutical Industries Ltd.
Competitive Summary:
Novartis and Ipsen lead in SSAs and PRRT, while Pfizer, Roche, and BMS are advancing immuno-oncology and targeted therapy research. AAA (a Novartis company) dominates the PRRT segment with Lutathera. The competitive landscape is shaped by orphan drug designations, clinical trial networks, and partnerships for rare cancer innovation.
Conclusion
The Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) Market, valued at USD 3.9 billion in 2024, is projected to reach USD 7.8 billion by 2034, growing at a CAGR of 7.2%. Rising prevalence, better diagnostics, and expanding therapeutic options are driving sustained growth.
Key Takeaways:
• SSAs remain the foundation of treatment, while PRRT and targeted therapies are expanding rapidly.
• North America and Europe dominate, but Asia-Pacific is the fastest-growing market.
• Orphan drug incentives and strong clinical pipelines are fueling competition.
• Precision oncology and AI-driven diagnostics will define the next decade of care.
The coming decade will see the GEP-NET market evolve through precision medicine, expanded PRRT use, and integration of immunotherapy, significantly improving outcomes for patients with this rare but increasingly recognized cancer.
This report is also available in the following languages : Japanese (消化管膵神経内分泌腫瘍市場), Korean (위장관췌장 신경내분비종양 시장), Chinese (胃肠胰神经内分泌肿瘤市场), French (Marché des tumeurs neuroendocrines gastro-entéro-pancréatiques), German (Markt für gastroenteropankreatische neuroendokrine Tumoren), and Italian (Mercato dei tumori neuroendocrini gastroenteropancreatici), etc.
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Hypercoagulability Market
https://exactitudeconsultancy.com/reports/71437/hypercoagulability-market
Idiopathic Thrombocytopenic Purpura Market
https://exactitudeconsultancy.com/reports/71439/idiopathic-thrombocytopenic-purpura-market
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https://exactitudeconsultancy.com/reports/71441/lymphocytopenia-market
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