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Protein A Resin Market Size to Reach $2.6 Billion by 2029 | Growth at 9.9% CAGR Forecast

08-26-2025 10:58 AM CET | Chemicals & Materials

Press release from: The Business Research Company

Protein A Resin

Protein A Resin

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What is the Projected Market Size of the Protein A Resin Industry?
The size of the protein a resin market has seen robust growth in the past few years. It's projected to rise from $1.66 billion in 2024 to $1.78 billion in 2025, with a compound annual growth rate (CAGR) of 7.2%. The marked growth in the past can be ascribed to the surge in biopharmaceutical production, the increasing acceptance of monoclonal antibodies, the expansion of research and development initiatives, a regulatory focus on the quality of biopharmaceuticals, and the growing incidence of chronic diseases.

What Will Be the Size of the Protein A Resin Market by 2029?
In the coming years, the protein a resin market is projected to experience robust growth, reaching a market value of $2.6 billion by 2029, with a compound annual growth rate (CAGR) of 9.9%. This anticipated growth during the forecast period can be credited to factors such as the advancements in biosimilar development, emphasis on cost-effectiveness, an upsurge in investments in bioprocessing establishments, the enlargement of the biopharmaceutical market in newly industrializing economies, and an increased need for personalized medicine. The forecast period will see major trends including the use of single-use systems, technological progression, demand from developing markets, strategic collaborations and partnerships, with a focus on sustainable methods.

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What Are the Key Drivers Accelerating Growth in the Protein A Resin Market?
Pharmaceutical companies' rising investment in research and development is forecasted to significantly boost the protein A resin market's growth. R&D, which involves the exploration and creation of novel drugs, treatments, technologies, or services to enhance patient health, is key in this process. Protein A resin is a common component in many chromatography assays, which are frequently used in pharmaceutical production procedures. For example, Roche Holding AG, a pharmaceutical firm based in Switzerland, ramped up its R&D spending to a record-setting $16.79 billion in 2022, marking a 3.7% increase from 2021. Similarly, US-based pharma company Merck increased its R&D budget by 10% in 2022 compared to 2021, with a total expenditure of $13.54 billion. This surge in R&D spending within the pharmaceutical sector is driving the expansion of the protein A resin market.

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How Is the Protein A Resin Market Segmented by Type, Application, and Region?
The protein a resin market covered in this report is segmented -

1) By Type: Natural Protein A, Recombinant Protein A
2) By Matrix Type: Agarose-Based Protein A, Glass Or Silica-Based Protein A, Organic Polymer-Based Protein A
3) By Application: Antibody Purification, Immunoprecipitation
4) By End User: Biopharmaceutical Manufacturers, Clinical Research Laboratories, Academic Institutes

Subsegments:
1) By Natural Protein A: Affinity Chromatography Resins, Protein Purification Resins, IgG Binding Resins
2) By Recombinant Protein A: Genetically Engineered Protein A Resins, Modified Protein A Resins, High-Capacity Protein A Resins

What Are the Key Trends Driving Growth in the Protein A Resin Market?
Key players in the protein A resin market strive to bolster product innovation, particularly in the development of high-performance affinity protein A resin. This is aimed at amplifying purification efficiency, trimming the production costs, and augmenting the overall yield in the biopharmaceutical manufacturing sphere. The specialized chromatography medium, also known as high-performance affinity Protein A resin, is explicitly engineered for the effective purification of antibodies and assorted proteins from intricate biological blends. For example, in July 2024, Purolite, Ltd., a US-based resin developer, producer, and distributor, introduced DurA Cycle A50. This revolutionary affinity Protein A resin is constructed to augment downstream purification within the biologics sector. The cutting-edge resin provides an extended resin life, lessens ligand leakage, and delivers exceptional performance, thus being a cost-efficient solution for antibody purification. The new product launch is tackling core industry problems such as cost reduction and reinforcing supply chain security through dual sourcing, consequently offering enhanced efficiency to clients.

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Who Are the Leading Companies Driving Growth in the Protein A Resin Market?
Major companies operating in the protein A resin market include GenScript Biotech Corporation, Agilent Technologies Inc., Repligen Corporation, Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Abcam plc, Novasep Holdings SAS, GE Healthcare Technologies Inc., Merck KGaA, Tosoh Bioscience LLC, Purolite Corporation, Kaneka Corporation, JSR Life Sciences Corporation, Danaher Corporation, Avantor Inc., Global Life Sciences Solutions USA, EMD Millipore Corp., Bio-Works Technologies AB, Avantor Performance Materials LLC, Avacta Life Sciences Limited, Purolite Lifesciences

Which Is the Leading Region in the Global Protein A Resin Market?
North America was the largest region in the Protein A Resin market in 2024. Europe is expected to be the fastest-growing region in the protein A resin market report during the forecast period. The regions covered in the protein A resin market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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