Global In Vivo Contract Research Organization Market Worth $7.19 Billion by 2029, Growing at 8.3% CAGR

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In Vivo Contract Research Organization Market Outlook: What Size And CAGR Are Anticipated By 2025?
The market size of in vivo contract research organization has experienced significant growth in the past few years. The market is projected to expand from $4.82 billion in 2024 to $5.23 billion in 2025, with a compound annual growth rate (CAGR) of 8.5%. The considerable growth seen in the past can be credited to factors such as the escalating costs of drug development, increasing cases of chronic diseases, expansion in pharmaceutical research and development investment, growth in the number of biotech start-ups, and a surge in demand for new therapeutics.

What Is the Expected CAGR for the In Vivo Contract Research Organization Market Growth Through 2029?
The market size for in vivo contract research organizations is projected to witness substantial growth in the coming years. It is forecasted to reach $7.19 billion by 2029, growing at a compound annual growth rate (CAGR) of 8.3%. Key drivers of this growth over the forecast period include the rising demand for precision medicine, worldwide growth of contract research organization services, increasing prevalence of personalized therapies, the escalating necessity for translational research, and the upsurge in orphan drugs. Some prominent trends during the forecast period encompass advancing imaging techniques for in vivo models, automated data processing and reporting, incorporation of omics technologies, the advent of cloud-based collaboration platforms, and developments in biologics biosimilars.

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What Are the Primary Drivers Behind In Vivo Contract Research Organization Market Growth?
The increasing emphasis on personalized medicine is anticipated to stimulate the expansion of the in vivo contract research organization market in the future. Personalized medicine adopts a medical strategy that adjusts treatment and prevention plans according to a person's genetic configuration, lifestyle, and environment, maximizing the potential for positive health outcomes. The heightened attention given to personalized medicine is due to the enhanced accessibility and affordability of genomic sequencing technologies; these advancements pave the way for more precise detection of genetic alterations, facilitating personalized therapies that increase patient outcomes and decrease the chances of trial-and-error in treatment. The rising emphasis on personalized medicine is creating a surge in demand within the in vivo CRO market as individualized preclinical studies that utilize specific animal models are required to assess the impacts of targeted therapies on unique genetic profiles. For example, in February 2024, as stated by the Personalized Medicine Coalition (PMC), a nonprofit organization based in the U.S., the FDA approved 16 novel personalized treatments in 2023, showing an increase from six in 2022. Personalized medicines represented over a third of all new drug approvals by the U.S. Food and Drug Administration (FDA) for the fourth year in a row. Therefore, the increasing focus on personalized medicine continues to drive the expansion of the in vivo contract research organization market.

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What Are the Key Segments Driving In Vivo Contract Research Organization Market Growth?
The in vivo contract research organization market covered in this report is segmented -

1) By Type: Rodent Based, Non-Rodent Based
2) By Type Of Service: Clinical Trial Services, Preclinical Services, Post-Market Services
3) By Good Laboratory Practice Type: Good Laboratory Practice Toxicology, Non Good Laboratory Practice
4) By Applications: Oncology, Cardiovascular Diseases, Infectious Diseases, Neurological Disorders, Other Applications
5) By End User: Pharmaceutical Companies, Biotechnology Companies, Contract Research Organizations (CROs), Academic And Research Institutes, Government And Regulatory Bodies

Subsegments:
1) By Rodent-Based: Mice Models, Rat Models, Genetically Engineered Rodents, Immunodeficient Rodents, Humanized Rodents
2) By Non-Rodent-Based: Canine Models, Non-Human Primate Models, Swine Models, Rabbit Models, Zebrafish Models

What Are the Technological Trends Impacting the In Vivo Contract Research Organization Market?
Key players within the in vivo contract research organization market are focusing their efforts on the creation of innovative solutions, such as advanced therapy incubator programs. These are designed to speed up the development of next-gen therapeutics and offer support for early-stage clinical research. An advanced therapy incubator program is a unique initiative that offers resources, guidance, and infrastructure to early-stage biotech companies, thereby accelerating the development of advanced therapies including gene, cell, and RNA-based treatments. Consider the example of Charles River Laboratories International Inc., a pharmaceutical firm based in the United States. In April 2025, it started its first ever advanced therapy incubator program cohort. The main objective of this forward-thinking initiative is to offer support to early-stage biotech firms that are focused on the development of next-generation therapies. Charles River's scientific expertise, top-notch laboratory infrastructure, and personalized in vivo models are made available through the program, enabling rapid proof-of-concept data generation. Furthermore, the program provides a practical preclinical environment for validating prospective therapeutic candidates, consequently reducing time-to-clinic and increasing the chances of regulatory success. The initiative serves as a vital bridge between academic innovation and clinical development, making it indispensable in propelling the field of advanced therapies forward.

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Who Are the Major Competitors in the Global In Vivo Contract Research Organization Market?
Major companies operating in the in vivo contract research organization market are Thermo Fisher Scientific Inc., IQVIA Inc., Labcorp Drug Development Inc., ICON plc, Pharmaceutical Product Development LLC, Eurofins Scientific SE, WuXi AppTec, Syneos Health Inc., Charles River Laboratories International Inc., Parexel International Corporation, Evotec SE, GemPharmatech Co Ltd., BIOQUAL Inc., Crown Bioscience Inc., PsychoGenics Inc., Janvier Labs SAS, Taconic Bioscience Inc., Xentech SAS, Pronexus Analytical AB, Altogen Labs Inc., AniLocus Inc.

Which Region Dominates the In Vivo Contract Research Organization Market Share in 2025?
North America was the largest region in the in vivo contract research organization market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in vivo contract research organization market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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