Press release
Amyloidosis Market Massive Growth opportunity Ahead
Amyloidosis Market
Amyloidosis is a rare, progressive disease characterized by the abnormal deposition of amyloid proteins in tissues and organs, leading to organ dysfunction and, in severe cases, life-threatening complications. The condition can affect the kidneys, heart, liver, and nervous system, making early detection and effective treatment essential. Historically underdiagnosed, amyloidosis is now gaining visibility due to advances in diagnostic tools, imaging technologies, and therapeutic innovations.
In 2024, the global Amyloidosis Market is valued at USD 6.8 billion and is projected to reach USD 13.2 billion by 2034, growing at a CAGR of 6.9% (2025-2034). Rising awareness among healthcare professionals, expansion of novel treatment options, and increased patient access to therapies are expected to drive market growth over the next decade.
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Market Overview
• Market Size 2024: USD 6.8 billion
• Forecast 2034: USD 13.2 billion
• CAGR (2025-2034): 6.9%
• Key Drivers: Advancements in diagnostic imaging and biopsy techniques, availability of disease-modifying therapies, rising incidence of multiple myeloma-related amyloidosis, and expanding rare disease research funding.
• Key Challenges: High treatment costs, limited awareness in developing regions, delayed diagnosis due to non-specific symptoms, and challenges in patient management.
• Leading Players: Johnson & Johnson (Janssen), Pfizer, Takeda, Bristol-Myers Squibb, Amgen, Novartis, AbbVie, Alexion Pharmaceuticals, Ionis Pharmaceuticals, GlaxoSmithKline.
The market is gradually transitioning from conventional symptomatic management to targeted disease-modifying therapies, offering new opportunities for patients and healthcare providers.
Segmentation Analysis
By Product
• Chemotherapy drugs
• Proteasome inhibitors
• Immunotherapy drugs
• Monoclonal antibodies
• Supportive care drugs
• Others
By Therapy
• Targeted therapy
• Chemotherapy
• Stem cell transplantation
• Immunotherapy
• Combination therapy
By Distribution Channel
• Hospital pharmacies
• Retail pharmacies
• Specialty clinics
• Online pharmacies
By End-Use
• Hospitals
• Cancer and rare disease centers
• Research institutes
• Homecare
By Application
• AL amyloidosis (primary amyloidosis)
• AA amyloidosis (secondary amyloidosis)
• Hereditary amyloidosis
• Wild-type transthyretin amyloidosis (ATTRwt)
• Dialysis-related amyloidosis
Summary of Segmentation
The AL amyloidosis segment dominates the market due to its high prevalence among patients with multiple myeloma. Targeted therapies and monoclonal antibodies are gaining rapid adoption, while hospital pharmacies remain the leading distribution channel due to the complexity of treatment regimens.
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Regional Analysis
• North America: Leads the market, driven by advanced healthcare infrastructure, strong research activity, high awareness, and availability of novel therapeutics.
• Europe: Strong market presence due to widespread adoption of stem cell therapies, clinical trial participation, and supportive regulatory frameworks.
• Asia-Pacific: Fastest-growing region, with increasing healthcare expenditure, rising diagnosis rates, and expanding pharmaceutical investments in rare disease treatment.
• Middle East & Africa: Moderate growth due to underdiagnosis and limited treatment options, though improving government initiatives are expanding access.
• Latin America: Steady growth led by Brazil and Mexico, supported by increasing availability of diagnostic and treatment facilities.
Regional Trends Summary
North America and Europe dominate due to advanced infrastructure and established rare disease programs, while Asia-Pacific is projected to record the highest CAGR of over 8% between 2025 and 2034, owing to rising investments and growing patient awareness.
Market Dynamics
Key Growth Drivers
• Advancements in diagnostic imaging and laboratory techniques.
• Rising availability of targeted therapies and monoclonal antibodies.
• Growing research funding and clinical trials for rare diseases.
• Increasing prevalence of AL amyloidosis linked to multiple myeloma.
Key Challenges
• High costs associated with therapies and prolonged treatment cycles.
• Delayed diagnosis due to overlapping symptoms with other conditions.
• Limited disease awareness among physicians in developing economies.
Latest Trends
• Growing focus on RNA-based therapies and gene-silencing approaches.
• Expansion of orphan drug designations by regulatory authorities.
• Increasing adoption of stem cell transplantation for eligible patients.
• Rising pharmaceutical investment in next-generation monoclonal antibodies.
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Competitive Landscape
Major Players
• Johnson & Johnson (Janssen)
• Pfizer
• Takeda
• Bristol-Myers Squibb
• Amgen
• Novartis
• AbbVie
• Alexion Pharmaceuticals
• Ionis Pharmaceuticals
• GlaxoSmithKline
Competitive Insights
The Amyloidosis Market is moderately consolidated, with leading pharmaceutical companies investing in targeted therapy development and clinical trials. Strategic collaborations, regulatory approvals, and orphan drug designations are central to their growth strategies. Start-ups and biotech firms are also contributing with innovative research in RNA therapies and next-generation biologics.
Conclusion
The global Amyloidosis Market is transitioning into a new growth phase, underpinned by improved diagnostic capabilities and a stronger pipeline of therapies. From USD 6.8 billion in 2024 to USD 13.2 billion by 2034, the market is expected to grow at a CAGR of 6.9%, offering promising opportunities for healthcare providers, researchers, and industry stakeholders.
• Opportunities: Asia-Pacific expansion, development of gene-based and RNA therapies, and increasing adoption of monoclonal antibodies.
• Challenges: High cost of therapies, limited awareness in emerging economies, and delayed patient diagnosis.
• Key Takeaway: Companies focusing on innovation, affordability, and patient-centric approaches will be best positioned to capitalize on the growing amyloidosis treatment market over the next decade.
This report is also available in the following languages : Japanese (アミロイドーシス市場), Korean (아밀로이드증 시장), Chinese (淀粉样变性市场), French (Marché de l'amylose), German (Amyloidose-Markt), and Italian (Mercato dell'amiloidosi), etc.
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