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High-Performance Liquid Chromatography Market Size to Reach $10.4 Billion by 2029 | Growth at 11.5% CAGR Forecast

08-25-2025 10:50 AM CET | Chemicals & Materials

Press release from: The Business Research Company

High-Performance Liquid Chromatography

High-Performance Liquid Chromatography

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What is the Projected Market Size of the High-Performance Liquid Chromatography Industry?
In recent years, the market size for high-performance liquid chromatography has seen significant growth. Projected to expand from $6.28 billion in 2024 to $6.73 billion in 2025, it will boast a compound annual growth rate (CAGR) of 7.2%. This upward trend in the past can be credited to factors such as the amplification in pharmaceutical research, heightened analysis in the food and beverage sector, increasing demand from environmental testing, enhancement in clinical diagnostic usage, as well as heightened research and development activities.

What Will Be the Size of the High-Performance Liquid Chromatography Market by 2029?
In the coming years, the market size for high-performance liquid chromatography will likely undergo swift expansion. It is projected to reach $10.4 billion in 2029, with a compound annual growth rate (CAGR) of 11.5%. This anticipated growth during the forecast period can be credited to factors such as the escalation in drug safety and quality assurance, demand from precision medicine, the widening realm of cannabis* testing, heightened environmental monitoring, and the increase in method development. Some key trends that can be expected during the forecast period are the advent of advanced detectors, the rise in high-throughput hplc, the adoption of green and sustainable hplc, a surge in uhplc usage, and an increase in lc-ms integration.

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What Are the Key Drivers Accelerating Growth in the High-Performance Liquid Chromatography Market?
The anticipated rise in chronic disease prevalence is predicted to fuel the high-performance liquid chromatography market's expansion. Chronic ailments such as cancer, heart disease, stroke, diabetes, and arthritis typically last for extended periods and necessitate extensive medical interventions. High-performance liquid chromatography (HPLC) is employed to analyze medications and verify their identity, provide quantitative details, and monitor treatment progress. This tool can further aid in deepening the understanding of normal and disease processes in the human body through biological and medical research conducted before drug approval, contributing to market growth. For example, in 2022, the American Cancer Society, a voluntary organization based in U.S., reported an expected 1.9 million new cancer diagnoses and 609,360 cancer-related deaths in the United States. Consequently, the surge in chronic disease prevalence is propelling the high-performance liquid chromatography market's growth.

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How Is the High-Performance Liquid Chromatography Market Segmented by Type, Application, and Region?
The high-performance liquid chromatography market covered in this report is segmented -

1) By Product: Instruments, Consumables, Accessories
2) By Application: Clinical Research, Diagnostics, Forensic, Other Applications
3) By End-User: Pharmaceutical And Biotechnology Industries, Diagnostic Laboratories, Food And Beverage Industry, Academic And Research Institutes, Other End-Users

Subsegments:
1) By Instruments: HPLC Systems, Ultra-High Performance Liquid Chromatography (UHPLC) Systems, Automated HPLC Systems
2) By Consumables: Columns, Mobile Phases, Sample Vials And Inserts
3) By Accessories: Detectors, Pumps And Flow Control Devices, Software And Data Analysis Tools.

What Are the Key Trends Driving Growth in the High-Performance Liquid Chromatography Market?
Leading firms in the market are innovating advanced HPLC technologies, such as unified high-performing liquid chromatography, suitable for numerous research uses. For example, in April 2024, Waters Corporation, an American life science company, introduced Alliance iS Bio. This system is purpose-built for biopharmaceutical applications, ensuring accurate and dependable separation of intricate biological molecules. It involves intelligent technology to aid QC analysts, diminishing operational mistakes and boosting system performance. The system eradicates up to 40% of usual errors, reducing the time required to probe failed runs and off-spec results. By improving workflow efficiency, it paves the way for speedier and more precise results in biopharmaceutical quality control procedures.

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Who Are the Leading Companies Driving Growth in the High-Performance Liquid Chromatography Market?
Major companies operating in the high-performance liquid chromatography market include Waters Corporation, Agilent Technologies Inc., Shimadzu Corporation, Thermo Fisher Scientific Inc., PerkinElmer Inc., Bio-Rad Laboratories Inc., Merck Millipore, Hitachi Ltd., Phenomenex Inc., JASCO Corporation, Gilson Inc., Knauer GmbH, SIELC Technologies, Tosoh Bioscience LLC, YMC Co. Ltd., GL Sciences Inc., Sepax Technologies Inc., Restek Corporation, Hamilton Company, ACE HPLC Columns, Advanced Chromatography Technologies Ltd., Analytical Sales and Services Inc., Chromatography Research Supplies Inc., Daicel Corporation, Eksigent Technologies LLC, Hichrom Limited

Which Is the Leading Region in the Global High-Performance Liquid Chromatography Market?
North America was the largest region in the high-performance liquid chromatography market analysis in 2024. Asia-Pacific is expected to be the fastest-growing region in the global high performance liquid chromatography market during the forecast period. The regions covered in the high-performance liquid chromatography market report include Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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