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Global DNA Synthesis Market Size, Share, and Forecast Analysis 2025-2029
Use ONLINE30 for 30% savings on global market reports and stay on top of tariff updates, market trends, and economic shifts worldwide.What Are the DNA Synthesis Market Size Forecast for 2025?
In recent years, there has been a remarkable growth in the size of the DNA synthesis market. It is expected to expand from $4.29 billion in 2024 to $5.18 billion in 2025, experiencing a compound annual growth rate (CAGR) of 20.7%. The historic expansion can be linked to the escalating utilization of DNA synthesis in academic genomic research, growing integration in agricultural biotechnology, burgeoning demand for primary DNA libraries in gene function exploration, increasing use of synthetic genes for vaccine creation, and rising applications in the modeling of infectious diseases.
What Is the Market Size Outlook for DNA Synthesis Until 2029?
In the coming years, the DNA synthesis market size is predicted to witness significant expansion. The market is set to escalate to $10.87 billion by 2029, with a compound annual growth rate (CAGR) of 20.4%. The growth anticipated during this period is due to a variety of factors including increasing implementation of AI and automation in DNA synthesis processes, enhanced collaboration between biotech firms and academic institutions, advent of DNA-based data storage technologies, a rising emphasis on environmentally friendly synthetic biology, and increased government initiatives promoting genomic innovation. The forecasted period will see prevailing trends such as the progression in enzymatic DNA synthesis techniques, enhanced incorporation of cloud-based bioinformatics into synthesis processes, evolution of decentralized DNA synthesis platforms, innovation in error-correction methods for synthetic genes, as well as progress in portable and on-demand DNA synthesis equipment.
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What Are the Major Factors Driving Demand in the DNA Synthesis Market?
The growth of the DNA synthesis market is predicted to surge due to the rising demand for personalized medicine. This type of medical practice customizes prevention strategies and treatments according to the individual's genetic profile, lifestyle, and environment for optimum therapeutic outcomes. The requirement for personalized medicine is growing predominantly due to advancements in genomics technologies. These technologies allow treatments to be customized according to the person's genetic profile, thereby increasing the effectiveness and minimizing side effects. DNA synthesis plays a crucial role in personalized medicine by facilitating the production of tailored DNA sequences used in gene editing, precision therapeutics, and diagnostic tools. This allows for more precise, effective, and personalized healthcare solutions. For example, in February 2024, the Personalized Medicine Coalition, an advocacy company based in the US, stated that in 2023, the FDA approved 16 new personalized treatments for patients with rare diseases, an increase from six in 2022. Hence, the burgeoning demand for personalized medicine propels the DNA synthesis market.
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How Are End-Use Segments Shaping the DNA Synthesis Market Outlook?
The dna synthesis market covered in this report is segmented -
1) By Service: Oligonucleotide Synthesis, Standard Oligonucleotide Synthesis, Custom Oligonucleotide Synthesis, Gene Synthesis, Custom Gene Synthesis, Gene Library Synthesis
2) By Method: Solid-Phase Synthesis, PCR-Based Enzyme Synthesis, Chip-Based Synthesis
3) By Application: Research And Development, Diagnostics, Therapeutics, Synthetic Biology, Other Applications
4) By End-User: Pharmaceutical And Biotechnology Companies, Contract Research Organizations (CROs) And Contract Development And Manufacturing Organizations(CDMOs), Academic And Research Institutes, Other End-Users
Subsegments:
1) By Oligonucleotide Synthesis: DNA Oligonucleotides, RNA Oligonucleotides, Modified Oligonucleotides
2) By Standard Oligonucleotide Synthesis: Unmodified Oligonucleotides, Modified Oligonucleotides, Purity Grades
3) By Custom Oligonucleotide Synthesis: Custom Length Oligos, Custom Modifications, Custom Purity Specifications
4) By Gene Synthesis: Synthetic Genes, Codon-Optimized Genes, Functional Genes
5) By Custom Gene Synthesis: Custom Sequence Design, Multi-fragment Assembly, Vector Cloning Services
6) By Gene Library Synthesis: Random Mutagenesis Libraries, Site-Directed Mutagenesis Libraries, Combinatorial Libraries
What Are the Strategic Trends Transforming the DNA Synthesis Market Landscape?
Leading firms in the DNA synthesis market are concentrating on creating unique solutions like synthetic deoxyribonucleic acid molecules to expedite the creation of gene therapies, diagnostic tools, and synthetic biology applications in a precise, efficient, and affordable manner. These synthetic DNA molecules are lab-made sequences of nucleotides, designed to reproduce or alter natural DNA for use in research, diagnostics, and biotechnology. In May 2025, Ribbon Biolabs, a synthetic biology firm based in Austria, introduced MiroSynth, a new category of sophisticated synthetic DNA molecules. It has been engineered for high-capacity, automated, and scalable production of lengthy and complicated deoxyribonucleic acid sequences for advanced biotech applications. Its unique features include superior accuracy in sequence assembly, increased strand length ability, and swift creation of elaborate genetic structures, making it perfect for research, therapy creation, and industrial biotech. The adaptable design of MiroSynth facilitates insertion into various workflows, enabling scientists and developers to boost innovation in genomics, synthetic biology, and personalized healthcare.
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Who Are the Prominent Companies in the DNA Synthesis Market by ?
Major companies operating in the dna synthesis market are Thermo Fisher Scientific Inc., Eurofins Scientific, GenScript Biotech Corporation, Twist Bioscience Corporation, Bioneer Corporation, DNA Script, Eton Bioscience, LGC Biosearch Technologies, Ansa Biotechnologies, Synbio Technologies, Quintara Biosciences, BaseClear B.V., IBA GmbH, Elegen Corporation, Biomatik Corporation, Bio Basic Inc., Evonetix Ltd., Camena Bioscience Ltd., Jena Bioscience GmbH, Viridos.
Which Region Is Expected to See the Highest CAGR in the DNA Synthesis Market?
North America was the largest region in the DNA synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the dna synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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