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Drug Repurposing Market Growth to be Driven by Emerging Trends | $53.42 Billion by 2029
Drug Repurposing
What is the Projected Market Size of the Drug Repurposing Industry?
The market size for repurposing drugs has seen robust growth in the past few years. It is expected that the market will expand from $34.12 billion in 2024, to $37.38 billion in 2025, showing a compound annual growth rate (CAGR) of 9.5%. Various factors have contributed to the growth experienced in the historic period. These include the escalating costs associated with novel drug development, more instances of drug failures during clinical trials, increased demand for quicker drug approval, the growing supply of off-patent drugs, and amplified funding from government and academic research.
What Will Be the Size of the Drug Repurposing Market by 2029?
The market size for drug repurposing is anticipated to witness substantial growth in the forthcoming years. It is projected to expand to $53.42 billion in 2029 with a compound annual growth rate (CAGR) of 9.3%. The anticipated increase during the forecast period can be credited to the rising demand for cost-effective treatments, an increase in investments by pharmaceutical firms, a surge in collaborations between biotech companies, and broader applications in areas like oncology and neurology. Key trends to watch in the predicted period include improvements in computational drug discovery tools, enhanced applications of AI and ML in drug repurposing, innovation in drug effectiveness predictive modeling, the application of big data analytics in drug screening, and advancement in identifying biomarkers.
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What Are the Key Drivers Accelerating Growth in the Drug Repurposing Market?
The surge in neurodegenerative diseases is poised to spur the expansion of the drug repurposing market. Neurodegenerative diseases encompass a variety of disorders marked by the progressive degeneration or loss of neurons which includes their death. This increasing trend can be attributed to improved life expectancy, with ageing recognized as the main risk factor leading to the gradual deterioration of neuronal function over time. Drug repurposing can aid these diseases by finding applicable existing drugs with established safety profiles that can be rerouted to target disease pathways, expediting the production of effective treatments. For example, in March 2023, data from the Alzheimer's Association, a US-based nonprofit health organization, showed approximately 6.7 million Americans aged 65 and older are living with Alzheimer's dementia, and it is projected that this number will increase to 13.8 million by 2060. Hence, the escalating prevalence of neurodegenerative diseases fuels the growth of the drug repurposing market.
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How Is the Drug Repurposing Market Segmented by Type, Application, and Region?
The drug repurposing market covered in this report is segmented -
1) By Type: Disease-Centric, Target-Centric, Drug-Centric
2) By Drug Molecules: Biologics, Small Molecule
3) By Therapeutic Area: Oncology, Neurology, Infectious Diseases, Cardiovascular Diseases, Autoimmune Disorders
4) By Route Of Administration: Oral, Intravenous, Topical, Inhalation, Intramuscular
5) By End-User: Pharmaceutical Companies, Research And Academic Institutes, Contract Research Organizations
Subsegments:
1) By Disease-Centric: Phenotypic Screening, Epidemiological Analysis, Clinical Observation-Based Repurposing
2) By Target-Centric: Protein Target Modulation, Pathway Modulation, Biomarker-Based Targeting
3) By Drug-Centric: Off-Target Activity Identification, Structure-Based Drug Repositioning, Adverse Effect-Based Repurposing
What Are the Key Trends Driving Growth in the Drug Repurposing Market?
Leading businesses in the drug repurposing market are concentrating on creating cutting-edge technologies such as artificial intelligence (AI)-powered drug-protein interaction models to expedite the discovery of new therapeutic applications for existing medicines. This method integrates artificial intelligence and machine learning to forecast how drugs interact with proteins across the human proteome, with large datasets improving the precision and reliability. For example, Cosmos Health Inc., a healthcare firm based in the US, introduced Cloudscreen 2.0, an innovative AI platform for drug repurposing, in July 2025. It's a state-of-the-art system designed to handle datasets over 100 times larger than its previous version, allowing for an in-depth investigation of drug-protein interactions. The platform, which includes mutagenesis data and tools for examining disordered proteins, is designed to target diseases like cancer, obesity, and diabetes. Moreover, the utilization of graphics processing unit (GPU)-based cloud computing makes processing scalable, positioning the platform as a crucial tool for speeding up research and development processes in drug repurposing across a variety of therapeutic domains.
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Who Are the Leading Companies Driving Growth in the Drug Repurposing Market?
Major companies operating in the drug repurposing market are F. Hoffmann-La Roche Ltd , International Business Machines Corporation (IBM), Bayer AG, Takeda Pharmaceutical Company Limited, Amgen Inc., Teva Pharmaceutical Industries Limited, Astellas Pharma Inc., UCB S.A., Eisai Co Ltd., Celltrion Inc., Alnylam Pharmaceuticals Inc., Evotec SE, BenevolentAI Limited, Insilico Medicine Inc., Cosmos Health Inc., Recursion Pharmaceuticals Inc., Pharnext S.A., Healx Ltd., Algernon Pharmaceuticals Inc., BioXcel Therapeutics Inc.
Which Is the Leading Region in the Global Drug Repurposing Market?
North America was the largest region in the drug repurposing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the drug repurposing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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