Steroid Refractory Acute Graft-Versus-Host Disease Market Expected to Gain Momentum Through 2032, According to DelveInsight

The Steroid Refractory Acute Graft-Versus-Host Disease market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage pipeline products will significantly revolutionize the Steroid Refractory Acute Graft-Versus-Host Disease market dynamics.

DelveInsight's "Steroid Refractory Acute Graft-Versus-Host Disease Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Steroid Refractory Acute Graft-Versus-Host Disease, historical and forecasted epidemiology as well as the Steroid Refractory Acute Graft-Versus-Host Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

To Know in detail about the Steroid Refractory Acute Graft-Versus-Host Disease market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Steroid Refractory Acute Graft-Versus-Host Disease Market Forecast
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Some of the key facts of the Steroid Refractory Acute Graft-Versus-Host Disease Market Report:
• The Steroid Refractory Acute Graft-Versus-Host Disease market size is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In May 2025, MaaT Pharma (EURONEXT: MAAT), a clinical-stage biotech company specializing in Microbiome Ecosystem TherapiesTM (MET) to improve cancer patient survival through immune modulation, announced that following the EMA Pediatric Committee's approval of its Pediatric Investigation Plan (PIP), the Data and Safety Monitoring Board (DSMB) has completed its final safety review of the pivotal Phase 3 ARES trial. This single-arm, open-label, multicenter European study evaluates the efficacy and safety of MaaT013 in patients with acute Graft-versus-Host Disease (GI-aGvHD) involving the gastrointestinal tract, who are receiving third-line treatment after being refractory to steroids and either refractory or intolerant to ruxolitinib.
• In December 2024, The FDA has approved remestemcel-L-rknd (Ryoncil) for treating pediatric patients aged two months and older with steroid-refractory acute graft-versus-host disease (GVHD), according to an agency announcement. The approval is supported by results from the multicenter, prospective, single-arm MSB-GVHD001 trial (NCT02336230), which evaluated the allogeneic bone marrow-derived MSC therapy in 54 children with steroid-refractory acute GVHD following allogeneic hematopoietic stem cell transplantation (HSCT).
• In December 2024, The FDA has granted approval to Mesoblast's allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy, remestemcel-L, for treating steroid-refractory acute graft-versus-host disease (GvHD) in children aged two months and older.
• The biopsy may help confirm Steroid Refractory Acute Graft-Versus-Host Disease diagnosis, but lacks sensitivity and specificity
• In around 35-50% of patients, aGVHD becomes refractory to systemic steroid therapy
• Key Steroid Refractory Acute Graft-Versus-Host Disease Companies: : MaaT Pharma, medac GmbH, AltruBio Inc., Incyte Corporation, and others
• Key Steroid Refractory Acute Graft-Versus-Host Disease Therapies: MC0518, Neihulizumab, T-Guard, Ruxolitinib, Apraglutide, and others
• The Steroid Refractory Acute Graft-Versus-Host Disease diagnosis is carried through laboratory analysis, imaging, and or endoscopic

Steroid Refractory Acute Graft-Versus-Host Disease Overview
Steroid-Refractory Acute Graft-Versus-Host Disease (SR-aGVHD) is a serious and life-threatening complication that occurs after an allogeneic stem cell or bone marrow transplant. In this condition, the donated immune cells attack the recipient's body tissues. Normally, steroids are the first line of treatment to control this immune response. However, in steroid-refractory cases, patients either do not respond to steroids or their symptoms worsen, making the disease harder to manage. SR-aGVHD often affects organs such as the skin, liver, and gastrointestinal tract and requires alternative therapies to improve survival and quality of life.

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Steroid Refractory Acute Graft-Versus-Host Disease Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Steroid Refractory Acute Graft-Versus-Host Disease Epidemiology Segmentation:
The Steroid Refractory Acute Graft-Versus-Host Disease market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Steroid Refractory Acute Graft-Versus-Host Disease
• Prevalent Cases of Steroid Refractory Acute Graft-Versus-Host Disease by severity
• Gender-specific Prevalence of Steroid Refractory Acute Graft-Versus-Host Disease
• Diagnosed Cases of Episodic and Chronic Steroid Refractory Acute Graft-Versus-Host Disease

Download the report to understand which factors are driving Steroid Refractory Acute Graft-Versus-Host Disease epidemiology trends @ Steroid Refractory Acute Graft-Versus-Host Disease Epidemiological Insights
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Steroid Refractory Acute Graft-Versus-Host Disease Market
The dynamics of the Steroid Refractory Acute Graft-Versus-Host Disease market are anticipated to change in the coming years owing to the expected launch of emerging therapies such as Itacitinib, MaaT013, and others during the forecasted period 2019-2032.

Steroid Refractory Acute Graft-Versus-Host Disease Therapies and Emerging Therapies
• MC0518: MaaT Pharma
• Neihulizumab: medac GmbH
• T-Guard: AltruBio Inc
• Ruxolitinib: Incyte Corporation

To know more about Steroid Refractory Acute Graft-Versus-Host Disease treatment, visit @ Steroid Refractory Acute Graft-Versus-Host Disease Medications
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Steroid Refractory Acute Graft-Versus-Host Disease Market Drivers
• Rising Incidence of Hematopoietic Stem Cell Transplantation (HSCT)
• High Unmet Medical Need
• Regulatory Support & Designations
• Ongoing Clinical Trials & Emerging Therapies
• Increased Awareness & Diagnosis

Steroid Refractory Acute Graft-Versus-Host Disease Market Barriers
• Complex Pathophysiology
• High Cost of Treatment
• Limited Patient Pool
• Adverse Effects of Therapies
• Delayed Diagnosis and Referral

Scope of the Steroid Refractory Acute Graft-Versus-Host Disease Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Steroid Refractory Acute Graft-Versus-Host Disease Companies: MaaT Pharma, medac GmbH, AltruBio Inc., Incyte Corporation, and others
• Key Steroid Refractory Acute Graft-Versus-Host Disease Therapies: MC0518, Neihulizumab, T-Guard, Ruxolitinib, Apraglutide, and others
• Therapeutic Assessment: Steroid Refractory Acute Graft-Versus-Host Disease current marketed and Steroid Refractory Acute Graft-Versus-Host Disease emerging therapies
• Migraine Market Dynamics: Steroid Refractory Acute Graft-Versus-Host Disease market drivers and barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Unmet Needs, KOL's views, Analyst's views, Steroid Refractory Acute Graft-Versus-Host Disease Market Access and Reimbursement

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Gaurav Bora
Email: info@delveinsight.com
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com

About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.
It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

This release was published on openPR.