Emerging Cartilage Degeneration Market Trends: Innovative Products Transforming The Cartilage Degeneration Market Shaping the Future of the Industry

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Cartilage Degeneration Market Size Growth Forecast: What to Expect by 2025?
In recent times, the market size for cartilage degeneration has witnessed robust growth. It is projected to rise from $12.63 billion in 2024 to $13.4 billion in 2025, with a compound annual growth rate (CAGR) of 6.2%. Factors such as an aging population, joint injuries, an obesity crisis, sports-related injuries, and limited self-repair capability have significantly contributed to growth in the historical period.

How Will the Cartilage Degeneration Market Size Evolve and Grow by 2029?
The market size for cartilage degeneration is forecasted to witness significant expansion in the coming years, and it is projected to reach a worth of $16.62 billion by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.5%. The anticipated growth during this period can be linked to advancements in regenerative medicine, the use of biologic injections, the development of tissue engineering solutions, precision medicine, and robotics-assisted surgery. Key trends for this period encompass stem cell therapies, the application of 3D printing in orthopedics, gene therapy for the repair of cartilage, customized rehabilitation programmes, and the use of telemedicine for post-treatment care.

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What Drivers Are Propelling the Growth of Cartilage Degeneration Market Forward?
The growth of the cartilage degeneration market is projected to be boosted by the escalating rates of obesity. Characterized by an unhealthy accumulation of body fat that could potentially harm an individual's health, obesity can trigger and expedite cartilage degeneration. It does this through the intensification of cartilage compressive forces and inflammatory cytokines. Additionally, obesity prompts several pathological transformations in the overall structure of the knee joint, such as abnormal strain on the joint, joint misalignment and muscle frailty. For example, in May 2023, the Government Digital Service of the UK, announced that approximately 63.8% of adults 18 or older were either overweight or obese in 2021-2022, marking an increase from 63.3% the prior year. Additionally, obesity was found in around 25.9% of adults, reflecting a rise of 25.2% from 2020 to 2021. Consequently, the escalating rates of obesity are stimulating the expansion of the cartilage degeneration market.

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Which Emerging Trends Are Transforming the Cartilage Degeneration Market in 2025?
Leading firms in the cartilage degeneration market are focusing on the production of creative solutions, such as Agili-C, to facilitate bone remodeling and cartilage renewal. Agili-C is a ready-to-use, cell-free implant designed to mend cartilage and osteochondral defects in both traumatic and osteoarthritic joints. For example, in July 2023, the initial commercial implantation of Agili-C was announced by CartiHeal Ltd., a medical device company based in Israel. The primary aim of the implant is to stimulate the natural regeneration of articular cartilage and subchondral bone, negating the need for cells or growth factors. The implant is crafted from naturally occurring calcium carbonate, or aragonite, sourced from coral exoskeletons. It encourages chondrocytes from nearby cartilage to move into the scaffold, creating an extracellular matrix. This approval enhances the credibility of the implant, providing reassurance to patients and healthcare professionals regarding its safety and efficacy as a treatment option.

What Are the Key Segments in the Cartilage Degeneration Market?
The cartilage degeneration market covered in this report is segmented -

1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures
2) By Application: Knee, Hip, Other Applications
3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes

Subsegments:
1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)
2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty
3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants
4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)
5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants
6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair
7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)
8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)

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Who Are the Key Players Shaping the Cartilage Degeneration Market's Competitive Landscape?
Major companies operating in the cartilage degeneration market report are Johnson & Johnson Services Inc., MEDIPOST Co. Ltd., Medtronic PLC, Stryker Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew PLC, B Braun Melsungen AG, Osiris Therapeutics Inc., Arthrex Inc., Conmed Corporation, Orthocell Ltd., Bioventus LLC, Aesculap Inc., Vericel Corporation, Anika Therapeutics Inc., Geistlich Pharma AG, MatTek Corporation, Breg Inc., Isto Biologics Inc., OrthoTrophix LLC, CellGenix GmbH, CartiHeal Inc., Cayenne Medical Inc., Collagen Solutions PLC, Regentis Biomaterials Ltd., Histogen Inc., BioTime Inc., CollPlant Holdings Ltd.

What Geographic Markets Are Powering Growth in the Cartilage Degeneration Market?
North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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