Hypertension Market Outlook 2032 - Clinical Trials, Market Size, Medication, Prevalence, Companies by DelveInsight

DelveInsight's latest report, "Hypertension - Market Insight, Epidemiology, and Market Forecast - 2032," provides a comprehensive assessment of the hypertension landscape, analyzing patient segmentation by age, stage, comorbidities, and treatment responsiveness across key geographies including the US, EU4 (Germany, France, Italy, Spain), the UK, and Japan.

While the market has long been served by generics and monotherapies, innovation is accelerating. The pipeline is evolving with novel fixed-dose combinations, therapies addressing treatment-resistant hypertension, and the integration of digital therapeutics and remote monitoring tools to improve adherence and control rates. Additionally, advances in biomarker-based risk stratification are enabling more personalized approaches to hypertension management.

The hypertension market is expected to grow steadily through 2032, driven by increasing disease burden, growing elderly populations, and heightened focus on early detection and home-based management. Pharmaceutical companies are also leveraging AI-powered platforms and real-world evidence to optimize treatment pathways and improve patient outcomes.

DelveInsight forecasts a shifting treatment paradigm in hypertension, as next-generation drugs, digital health solutions, and precision medicine converge to enhance long-term control and reduce cardiovascular events, unlocking significant market opportunities across developed and emerging healthcare systems.

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Some of the key insights of the Hypertension Market Report:
• The hypertension market is anticipated to expand steadily at a consistent CAGR from 2024 through 2032.
• Approximately 1.3 billion adults globally are affected by hypertension.
• DelveInsight estimates that the US represented the largest PAH market in 2024, valued at roughly USD 6 billion, followed by Japan and Germany.
• In 2023, the US had around 18 million prevalent cases of chronic pulmonary hypertension, with projections indicating a substantial increase by 2032.
• Across the 7MM, there were about 21 million prevalent cases of ocular hypertension in 2023, of which 13 million were diagnosed.
• In April 2025, Orchestra BioMed Holdings, Inc. announced that the FDA granted Breakthrough Device Designation (BDD) for its atrioventricular interval modulation (AVIM) therapy, highlighting its potential to treat uncontrolled hypertension and cardiovascular risk in over 7.7 million U.S. patients. AVIM is being evaluated in the BACKBEAT global pivotal study in collaboration with Medtronic.
• In March 2025, Liquidia Corporation (NASDAQ: LQDA) reported that the FDA accepted the resubmission of its NDA for YUTREPIATM (treprostinil) inhalation powder, targeting pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD).
• In March 2025, Scienture Holdings, Inc. completed a draw on its Equity Line of Credit (ELOC) to support the commercial launch of ArbliTM (losartan potassium) Oral Suspension and temporarily suspended further draws for 30 trading days or until its stock reaches $10 per share.
• In January 2025, Mineralys Therapeutics, Inc. received FDA approval for its IND application to initiate a Phase II clinical trial evaluating lorundrostat for obstructive sleep apnea (OSA) and hypertension, with the trial starting in Q1 2025.
• In November 2024, Medtronic received CMS transitional pass-through (TPT) payment approval for the Symplicity Spyral renal denervation catheter, effective January 1, 2025, enhancing patient access under Medicare's Outpatient Prospective Payment System. The device also holds FDA breakthrough device designation.
• Emerging therapeutic candidates for hypertension include Ralinepag, YUTREPIA, Lorundrostat, Seralutinib, Vardenafil, L606, Molgramostim nebulizer solution, Sargramostim, among others.
• Leading companies in the hypertension treatment space include Merck, Bristol Myers Squibb, United Therapeutics, Liquidia Technologies, Tenax Therapeutics, Respira Therapeutics, Gossamer Bio, Pharmosa Biopharm, Aerovate Therapeutics, Insmed, Novartis, Cumberland Pharmaceuticals, Sumitomo Pharma (Enzyvant Therapeutics), Cereno Scientific, AstraZeneca, Savara, Nobelpharma, Partner Therapeutics, and others.

To know in detail about the hypertension market outlook, drug uptake, treatment scenario, and epidemiology trends, click here: https://www.delveinsight.com/report-store/hypertension-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Hypertension Overview
Hypertension, commonly referred to as high blood pressure, is a chronic medical condition in which the force of blood against the arterial walls is persistently elevated. It is a major risk factor for cardiovascular diseases, including heart attack, stroke, heart failure, and renal dysfunction. Globally, approximately 1.3 billion adults are affected by hypertension, making it one of the most prevalent non-communicable diseases worldwide.

Hypertension is classified as primary (essential) or secondary. Primary hypertension, the most common form, develops gradually with no identifiable cause, whereas secondary hypertension results from underlying medical conditions such as kidney disease, endocrine disorders, or certain medications. Early detection and management are critical to prevent long-term complications. Diagnosis typically involves regular blood pressure monitoring, laboratory evaluations, and assessment of comorbidities.
Management strategies include lifestyle modifications such as dietary sodium reduction, weight control, regular physical activity, and smoking cessation, alongside pharmacological therapies.
Current treatments encompass a wide range of antihypertensive agents, including ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, diuretics, and novel therapies under clinical development.
Recent advancements include device-based interventions such as renal denervation and investigational regenerative and gene-based therapies. Despite the availability of effective treatments, hypertension remains a significant global health challenge due to underdiagnosis, inadequate adherence to therapy, and disparities in healthcare access. Ongoing research and technological innovation continue to improve outcomes and expand therapeutic options. Hypertension, or high blood pressure, remains one of the most widespread and modifiable risk factors for cardiovascular disease globally. Despite being highly prevalent, with over 1.3 billion affected worldwide, it often goes undiagnosed or inadequately managed, leading to increased risks of heart attack, stroke, and kidney failure.

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Hypertension Epidemiology
The epidemiology section offers an overview of historical, current, and projected trends in the seven major countries (7MM) from 2019 to 2032. It helps identify the factors influencing these trends by examining various studies and perspectives from key opinion leaders. Additionally, the section provides an in-depth analysis of the diagnosed patient population and future trends.

Hypertension Epidemiology Segmentation:
The hypertension market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM, segmented into:
• Diagnosed Prevalent Cases
• Gender-specific Diagnosed Prevalent Cases
• Age-Specific Diagnosed Prevalent Cases
• Severity-Specific Diagnosed Prevalent Cases

Hypertension Drugs Uptake and Pipeline Development Activities
The Drug Uptake section offers a detailed analysis of the adoption trends of newly launched and upcoming therapies for Hypertension throughout the study period. It evaluates patient adoption rates, market penetration, and the commercial performance of each therapy, providing a clear understanding of the factors driving or hindering the market acceptance of these treatments.

The Therapeutics Assessment further highlights the Hypertension drugs, demonstrating the most rapid uptake. It examines the underlying drivers contributing to their swift adoption and compares the market share of these therapies to identify those gaining significant traction.

Additionally, the report provides an in-depth overview of the current therapeutic pipeline for Hypertension, covering investigational drugs at various stages of development. It profiles the key pharmaceutical and biotech companies actively involved in advancing targeted treatments and presents the latest updates on partnerships, mergers and acquisitions, licensing deals, and other strategic developments shaping the future of Hypertension therapeutics.

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Hypertension Market Outlook
The hypertension market is expected to experience steady growth from 2023 to 2032, driven by the rising global prevalence of the condition and increasing demand for effective treatments. Recent market expansion has been supported by research and development efforts that have introduced innovative drugs and therapies. Companies such as Mineralys Therapeutics Inc. and CinCor Pharma are advancing mid- to late-stage assets, and the anticipated approvals of these therapies during the forecast period are likely to further accelerate market growth, resulting in a significant CAGR for the hypertension therapeutic segment.

Current hypertension management combines lifestyle modifications-such as a low-sodium diet, regular exercise, weight control, reduced alcohol intake, and smoking cessation-with pharmacological therapies. Common drug classes include diuretics, beta-blockers, ACE inhibitors, ARBs, calcium channel blockers, and other antihypertensives, used alone or in combination. Studies indicate ACE inhibitors, often combined with thiazide diuretics, are widely prescribed, with beta-blockers also commonly used. Prescription patterns often evolve during treatment.

Several novel therapies are in development to improve management, especially for treatment-resistant hypertension, and are expected to enter the market between 2023 and 2032. The 7MM hypertension market is projected to undergo notable growth during this period. However, challenges such as poor patient adherence and limited access to newer medications could restrict market expansion despite overall positive trends.

Hypertension Market Drivers
1. High Prevalence and Global Burden: With approximately 1.3 billion adults affected worldwide, hypertension represents a significant unmet medical need, driving demand for effective therapies.
2. Advancements in Pharmacological Treatments: Continuous development of novel antihypertensive agents, including combination therapies and targeted biologics, is expanding treatment options.
3. Device-Based Innovations: Technologies such as renal denervation catheters and implantable monitoring devices are improving blood pressure control in resistant cases.
4. Improved Early Diagnosis: Enhanced screening programs, wearable blood pressure monitors, and digital health platforms facilitate timely intervention.
5. Rising Awareness and Healthcare Access: Increased awareness among patients and clinicians, along with expanding healthcare infrastructure in emerging markets, supports higher treatment uptake.

Hypertension Market Barriers
1. High Treatment Costs: Advanced therapies and device-based interventions can be expensive, limiting accessibility in low-resource settings.
2. Patient Non-Adherence: Long-term adherence to lifestyle modifications and medication regimens remains a challenge, impacting treatment efficacy.
3. Limited Access to Specialized Care: Availability of advanced therapies and interventions is often restricted to specialized centers.
4. Regulatory and Reimbursement Challenges: Delays in approvals, stringent regulatory requirements, and reimbursement limitations can slow market adoption of innovative therapies.

Hypertension Pipeline Outlook and Drugs Uptake
Lorundrostat: Mineralys Therapeutics Inc.
Lorundrostat is an orally administered, highly selective aldosterone synthase inhibitor being developed to treat uncontrolled and resistant hypertension. By targeting CYP11B2-the enzyme responsible for aldosterone production-Lorundrostat aims to lower aldosterone levels. The drug has recently completed a Phase II clinical trial.

Baxdrostat: CinCor Pharma
Baxdrostat is an investigational therapy that selectively inhibits aldosterone synthase, a key target in hypertension management. It is currently undergoing Phase II clinical evaluation.

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Scope of the Hypertension Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan].
• Key Hypertension Companies: Merck, Bristol Myers Squibb, United Therapeutics, Liquidia Technologies, Tenax Therapeutics, Respira Therapeutics, Gossamer Bio, Pharmosa Biopharm, Aerovate Therapeutics, Insmed, Novartis, Cumberland Pharmaceuticals, Sumitomo Pharma (Enzyvant Therapeutics), Cereno Scientific, AstraZeneca, Savara, Nobelpharma, Partner Therapeutics, and others.
• Key Hypertension Therapies: Ralinepag, YUTREPIA, Lorundrostat, Seralutinib, Vardenafil, L606, Molgramostim nebulizer solution, Sargramostim, and others.
• Hypertension Therapeutic Assessment: Hypertension currently marketed, and Hypertension emerging therapies.
• Hypertension Market Dynamics: Hypertension market drivers and Hypertension market barriers.
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies.
• Hypertension Unmet Needs, KOL's views, Analyst's views, Hypertension Market Access and Reimbursement.

Contact Us:
Ankit Nigam
Manager Marketing
info@delveinsight.com
+14699457679

About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.

This release was published on openPR.