EasyMount® Ussing Chambers from Physiologic Instruments Advance CFTR and Cystic Fibrosis Research

Venice, FL - August 13, 2025 - Physiologic Instruments announced today that its EasyMount® Ussing chamber systems, a leading solution for epithelial transport measurement, have been cited in peer-reviewed studies supporting the development of CFTR modulator therapies for cystic fibrosis.

Researchers investigating treatments such as ivacaftor, lumacaftor, and the elexacaftor/tezacaftor/ivacaftor combination have used EasyMount chambers to measure transepithelial ion transport in primary airway and nasal epithelial cultures. These measurements are essential for assessing improvements in chloride and bicarbonate secretion - key indicators of CFTR channel function recovery.

"Our goal is to provide scientists with tools that ensure consistent, high-quality data for decision-making," said D. Thompson, Director of Marketing Communications at Physiologic Instruments. "EasyMount Ussing chambers streamline experimental setup and maintain the precision required for translational and clinical research."

The EasyMount platform integrates with Physiologic Instruments' VCC-series voltage-current clamps to perform short-circuit current (Isc) recordings under controlled temperature and gas conditions. This enables accurate, reproducible evaluation of drug-induced CFTR function changes, helping researchers validate therapeutic impact before clinical trials.

Physiologic Instruments designs and manufactures Ussing chambers, voltage-current clamps, and data acquisition systems for epithelial transport and barrier function research. The company's equipment is trusted in academic laboratories, pharmaceutical development programs, and clinical research worldwide.

For more information, visit: https://www.physiologicinstruments.com

795 Commerce Dr, Ste 7
Venice, FL 34292 USA

Physiologic Instruments is a leading manufacturer of precision laboratory equipment for epithelial transport and barrier function research. The company's flagship EasyMount® Ussing Chamber Systems and VCC-series voltage-current clamps are trusted by academic institutions, pharmaceutical companies, and clinical research laboratories worldwide.

Specializing in high-fidelity measurement of short-circuit current (Isc), transepithelial electrical resistance (TER/TEER), and ion transport dynamics, Physiologic Instruments provides researchers with tools designed for reproducibility, efficiency, and accuracy.

Applications for the company's systems include:

Cystic fibrosis drug development and CFTR function testing

Gastrointestinal physiology and nutrient absorption studies

Airway and lung epithelial barrier research

Permeability and transport assays for pharmaceutical screening

Founded on a commitment to quality engineering, scientific support, and long-term reliability, Physiologic Instruments continues to empower scientists worldwide with equipment that accelerates discovery and supports translational medicine.

For more information, visit https://www.physiologicinstruments.com

This release was published on openPR.