Herpes Simplex Virus Treatment Market Driven by Rising Prevalence and Antiviral Innovations | Sanofi S.A., GlaxoSmithKline Plc., Genocea Biosciences, Inc., Vical, Inc, Novartis, Pfizer, Abbott Laboratories

The global Herpes Simplex Virus Treatment Market size was valued USD 2.63 billion in 2024, and is estimated to reach USD 4.38 billion by 2033, growing at a CAGR of 7.6% during the forecast period (2025-2033).

Herpes Simplex Virus Treatment Market Report by DataM Intelligence offers a detailed assessment of the global pharmaceutical and healthcare landscape, highlighting market size, key players, and critical growth drivers. With growing unmet needs in antiviral resistance, recurrent infection management, and therapeutic innovation, the report delivers strategic insights for stakeholders from 2025 to 2033.

At ESCMID 2025, promising data was presented on ABI-5366, a novel oral helicase primase inhibitor demonstrating potential for weekly or monthly dosing to effectively suppress recurrent genital herpes. Additionally, a breakthrough from Japan has emerged: bispecific nanobody dimers (Nb14-32-Fc) targeting glycoprotein D (gD) of HSV showed potent neutralization in vitro and in vivo, paving the way for next-generation biologic antivirals.

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The HSV treatment market includes antiviral medications, topical creams, and vaccines in development for managing HSV-1 and HSV-2 infections. Market growth is driven by high prevalence rates, ongoing research into therapeutic vaccines, and increasing awareness about sexually transmitted infections.

Herpes Simplex Virus Treatment Market Competitors Overview:

Sanofi S.A., GlaxoSmithKline Plc., Genocea Biosciences, Inc., Vical, Inc, Novartis, Pfizer, Abbott Laboratories, Sun Pharmaceuticals, Valeant Pharmaceuticals, Teva Pharmaceutical.

Important Industry Updates of 2023, 2024 and 2025:

March 2025 - AiCuris Anti-infective Cures GmbH secured €75 million in funding to accelerate late-stage development of pritelivir, an oral helicase-primase inhibitor for acyclovir-resistant HSV infections, and to expand its antiviral pipeline.
June 2025 - Vaxart, Inc. advanced its oral HSV therapeutic vaccine candidate into Phase II trials, attracting strategic interest from immunotherapy-focused venture groups, though no disclosed M&A occurred.

Methodology and Scope

The Herpes Simplex Virus Treatment Market Report is built on a rigorous research methodology that integrates primary interviews, expert insights, and validated secondary data from company reports, industry publications, and reliable databases. Utilizing both bottom-up and top-down approaches, the analysis ensures high data accuracy through triangulation. The report covers current market dynamics, growth opportunities, and key strategic developments across global and regional markets.

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Herpes Simplex Virus Treatment Market Segments Overview:

By Vaccine (GEN-003, VCL-HB01, HSV529, Others), By Indication (HSV-1 (Oral Herpes), HSV-2 (Genital Herpes))

Regional Overview for Herpes Simplex Virus Treatment Market:

⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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