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Chemotherapy-Induced Peripheral Neuropathy Market Size, Share and Growth Report, 2034

08-08-2025 12:14 PM CET | Business, Economy, Finances, Banking & Insurance

Press release from: Exactitiude Consultancy

Chemotherapy-Induced Peripheral Neuropathy Market

Chemotherapy-Induced Peripheral Neuropathy Market

Introduction: A Market Driven by the Urgency of Quality-of-Life Care in Oncology
Chemotherapy-Induced Peripheral Neuropathy (CIPN) has emerged as one of the most challenging complications for cancer patients undergoing chemotherapy. As cancer treatment regimens improve survival rates, the quality of life during and after therapy has become a major focus for oncologists and healthcare providers. CIPN, characterized by pain, numbness, tingling, and functional impairment in the extremities, affects up to 68% of patients receiving neurotoxic chemotherapy drugs. The global market for CIPN treatments and management solutions is gaining significant traction as pharmaceutical innovation, improved diagnostics, and patient-centered care converge to address this unmet need.
The CIPN market, which stood at USD 1.75 billion in 2024, is projected to reach USD 3.62 billion by 2034, growing at a compound annual growth rate (CAGR) of 7.6% during the forecast period. This growth is underpinned by an increasing global cancer incidence, expansion of oncology drug pipelines, and rising adoption of supportive care protocols.

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Market Overview: Key Highlights
• Market Size 2024: USD 1.75 billion
• Forecast 2034: USD 3.62 billion
• CAGR (2024-2034): 7.6%
• Major Drivers: Rising cancer prevalence, oncology R&D investment, adoption of patient quality-of-life standards.
• Key Challenges: Lack of universally effective therapies, limited awareness in low-income regions, regulatory approval delays.
• Leading Players: Novartis AG, Pfizer Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Eli Lilly and Company, GlaxoSmithKline plc, NeuroMetrix Inc., Biohaven Pharmaceuticals, PledPharma AB, Astellas Pharma Inc.

Segmentation Analysis
By Drug Type
• Antidepressants (e.g., duloxetine, amitriptyline)
• Anticonvulsants (e.g., gabapentin, pregabalin)
• Opioids & Non-opioid Analgesics
• Topical Agents (lidocaine, capsaicin)
• Nutritional Supplements & Neuroprotective Agents

By Chemotherapy Agent Causing CIPN
• Platinum-based drugs (cisplatin, oxaliplatin)
• Taxanes (paclitaxel, docetaxel)
• Vinca alkaloids (vincristine, vinblastine)
• Bortezomib and other proteasome inhibitors

By Distribution Channel
• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies

By End User
• Hospitals & Oncology Clinics
• Ambulatory Care Centers
• Homecare Settings

Segmentation Summary:
The antidepressant segment currently leads due to strong clinical evidence supporting duloxetine as the only drug with significant guideline-based recommendations for CIPN management. However, the nutraceutical and neuroprotective segment is expected to grow rapidly as research into oxidative stress modulation gains momentum.

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Regional Analysis
North America
• Largest market share (~38% in 2024) due to advanced oncology infrastructure and high adoption of guideline-based CIPN management.
• Robust pipeline of neuroprotective drugs and high awareness levels among oncologists.
Europe
• Strong presence of supportive oncology care programs, especially in Germany, France, and the UK.
• Stringent reimbursement policies but increasing inclusion of CIPN management in cancer care protocols.
Asia-Pacific
• Fastest-growing region with a CAGR of over 9% due to rising cancer incidence in China, India, and Japan.
• Increasing government healthcare investments and expanding oncology drug access.
Middle East & Africa
• Market growth driven by expanding cancer treatment centers in GCC countries.
• Limited awareness and access in sub-Saharan Africa remain challenges.
Latin America
• Brazil and Mexico lead adoption due to improving cancer screening and treatment programs.
• Growth potential as regional pharmaceutical players enter supportive oncology care.

Regional Summary:
North America dominates the market, but Asia-Pacific presents the most lucrative growth opportunities, driven by large patient pools and rapid healthcare modernization.

Market Dynamics
Key Growth Drivers
1. Rising Cancer Incidence: WHO data projects over 30 million new cancer cases annually by 2040, driving chemotherapy usage.
2. Pharmaceutical Innovation: Development of novel neuroprotective agents and repurposing of existing drugs.
3. Clinical Guideline Integration: Inclusion of CIPN management in oncology care pathways boosts adoption rates.
4. Growing Patient Awareness: Demand for quality-of-life interventions post-chemotherapy.

Key Challenges
• Lack of curative treatment for CIPN-current therapies are mostly symptomatic.
• Limited physician training in CIPN recognition in low- and middle-income countries.
• Difficulty in conducting large-scale CIPN clinical trials due to variability in onset and severity.

Latest Trends
• Use of wearable neurostimulation devices for pain management.
• Advancements in biomarker-based prediction of CIPN risk.
• Increasing focus on combination therapies (drug + non-drug interventions).
• Telehealth expansion for CIPN symptom monitoring and medication adjustments.

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Competitor Analysis
Major Players
• Novartis AG
• Pfizer Inc.
• Amgen Inc.
• Teva Pharmaceutical Industries Ltd.
• Eli Lilly and Company
• GlaxoSmithKline plc
• NeuroMetrix Inc.
• Biohaven Pharmaceuticals
• PledPharma AB
• Astellas Pharma Inc.
• Kyowa Kirin Co., Ltd.
• Cipla Ltd.
• Mylan N.V.
• Sorrento Therapeutics, Inc.
• Aptinyx Inc.

Competitive Summary:
The market is moderately consolidated, with large pharma companies focusing on expanding their supportive care portfolios through both new drug development and acquisitions. Start-ups and mid-sized firms are innovating in device-based CIPN therapies, creating a hybrid drug-device competitive landscape.

Conclusion: Outlook and Opportunities
The Chemotherapy-Induced Peripheral Neuropathy market is on a strong growth trajectory through 2034, fueled by the dual push of increasing cancer prevalence and the urgent need for quality-of-life interventions. While no definitive cure exists, the accelerating pace of research into both pharmaceutical and device-based solutions offers hope for more effective, patient-friendly options.

This report is also available in the following languages : Japanese (腫瘍内癌治療市場), Korean (종양 내 암 치료 시장), Chinese (肿瘤内癌症治疗市场), French (Marché des thérapies intratumorales contre le cancer), German (Markt für intratumorale Krebstherapien), and Italian (Mercato delle terapie contro il cancro intratumorale), etc.

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About Us
Exactitude Consultancy is a market research & consulting services firm which helps its client to address their most pressing strategic and business challenges. Our market research helps clients to address critical business challenges and also helps make optimized business decisions with our fact-based research insights, market intelligence, and accurate data.
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