B-Cell Lymphomas Market Forecast 2032: Clinical Trials, EMA, PDMA, FDA Approvals, Medication, Therapies, Treatment Market, Revenue, Statistics and Companies by DelveInsight

(Albany, USA) DelveInsight's "B-Cell Lymphomas Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of B-Cell Lymphomas, historical and forecasted epidemiology as well as the B-Cell Lymphomas market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The B-Cell Lymphomas market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted B-Cell Lymphomas market size from 2019 to 2032, segmented by seven major markets. The Report also covers current B-Cell Lymphomas treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the B-Cell Lymphomas market.

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Some facts of the B-Cell Lymphomas Market Report are:
• According to DelveInsight, B-Cell Lymphomas market size is expected to grow at a decent CAGR by 2032.
• Leading B-Cell Lymphomas companies working in the market are Oncternal Therapeutics, Inc., ZAI Lab, Pfizer, Xynomic Pharmaceuticals, SystImmune Inc., Autolus Limited, Vincerx Pharma, Ubix Therapeutics, Biomea Fusion Inc., Shanghai Hengrui Pharmaceutical, BeiGene, Hanmi Pharmaceutical, Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Merck Sharp & Dohme LLC, Sanofi, InnoCare Pharma, Allogene Therapeutics, Cellular Biomedicine Group Ltd., Genentech, Philogen, Aleta Biotherapeutics, Incyte Corporation, Fundamenta Therapeutics, Juventas Cell Therapy, Shanghai Hengrui Pharmaceutical Co., Guangzhou Lupeng Pharmaceutical, TG Therapeutics Inc., Roche, 2seventy bio, AstraZeneca, Nektar Therapeutics, ADC Therapeutics, Genor Biopharma, Pacylex Pharmaceuticals, Antengene Corporation, Zhejiang DTRM Biopharma, Shanghai Cell Therapy Group Co., Nanjing Legend Biotech Co.and others, and others.
• Key B-Cell Lymphomas Therapies expected to launch in the market are Epeleuton, Tipelukast, TA 270, MW 001, PTC 857, Baicalein, VLX 1005, Research programme: 5-B-Cell Lymphoma Inhibitor (LOX Inhibitor), and others.
• In July 2025, FDA rejects Roche's Columvi in earlier diffuse large B-cell lymphoma, citing lackluster US data
• In July 2025, Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter (CRL) for Genentech's supplemental Biologics License Application (sBLA) for Columvi® (glofitamab-gxbm) in combination with gemcitabine and oxaliplatin (GemOx) for the treatment of people with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who are not candidates for autologous stem cell transplant.
• In March 2025, BeiGene announced a study is to compare how well sonrotoclax plus zanubrutinib works versus zanubrutinib plus placebo in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This study will also look at the safety of sonrotoclax plus zanubrutinib versus zanubrutinib plus placebo.
• In March 2025, Celgene announced a study is to compare the effectiveness and safety of golcadomide in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy vs placebo in combination with R-CHOP chemotherapy in participants with previously untreated high-risk large B-cell lymphoma (LBCL).
• In March 2025, Hoffmann-La Roche announced a study is to compare the efficacy and safety of glofitamab in combination with polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone (Pola-R-CHP) vs Pola-R-CHP in participants with previously untreated CD20-positive large B-cell lymphoma (LBCL).
• In March 2025, Allogene Therapeutics announced a study is conducted in 2 consecutive parts that will be enrolled continuously. In Part A of the study, participants with MRD are randomized to one of two treatment arms or an observation arm. Treatment includes cema-cel following a lymphodepletion regimen of fludarabine and cyclophosphamide administered with or without the anti-CD52 monoclonal antibody, ALLO-647. Part A will culminate with the selection of the lymphodepletion regimen to advance to Part B. Part B will evaluate the selected lymphodepletion regimen followed by cema-cel as compared with observation.
• In March 2025, Regeneron Pharmaceuticals announced a study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on patients with previously treated aggressive B-cell non-Hodgkin lymphoma whose cancer has stopped responding to treatment (also known as 'refractory') or has returned (also known as 'relapsed'). The aim of the study is to see how safe, tolerable and effective the study drug is when given alone.
• In June 2024, M.D. Anderson Cancer Center announced results of a Phase 2 Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or Refractory Patients With Large B Cell Lymphoma
• In May 2024, Astellas Pharma Inc announced results of a First-in-Human, Phase 1 Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of a Single-Induction Dose of convertibleCARTM-T Cells Armed With MicAbodyTM Protein (ASP2802) Followed by Maintenance Booster Doses of the MicAbody Protein in Patients With CD20-Positive Relapsed or Refractory B-Cell Lymphomas.
• In April 2024, TG Therapeutics, Inc has announced results of a Phase 1 First-in-Human Study of Bispecific Antibody TG-1801 in Subjects With B-Cell Lymphoma

B-Cell Lymphomas Overview
B-cell lymphomas are a diverse group of blood cancers that originate in B lymphocytes-an essential component of the immune system responsible for producing antibodies. These malignancies fall under the broader category of non-Hodgkin lymphomas (NHL) and vary widely in their behavior, prognosis, and treatment responses. Common subtypes include Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), and Burkitt Lymphoma.
The pathogenesis of B-cell lymphomas typically involves genetic mutations, chromosomal translocations, and dysregulated B-cell signaling pathways, such as those involving B-cell receptors (BCR) and Bruton's Tyrosine Kinase (BTK). Advances in molecular biology have led to targeted therapies, such as anti-CD20 monoclonal antibodies (e.g., rituximab), BTK inhibitors (e.g., ibrutinib, zanubrutinib), and CAR T-cell therapies.
Treatment strategies are subtype-specific and may include chemotherapy, immunotherapy, targeted therapy, or stem cell transplantation. Prognosis depends on factors like lymphoma subtype, stage, and patient comorbidities.
Ongoing research is focused on improving outcomes through biomarker-driven approaches, novel agents, and combination regimens. As precision medicine continues to evolve, the future of B-cell lymphoma treatment holds promise for more personalized and effective therapies.

Learn more about B-Cell Lymphomas treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ B-Cell Lymphomas Treatment Market - https://www.delveinsight.com/sample-request/b-cell-lymphomas-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

B-Cell Lymphomas Market
The B-Cell Lymphomas market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted B-Cell Lymphomas market trends by analyzing the impact of current B-Cell Lymphomas therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the B-Cell Lymphomas market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated B-Cell Lymphomas market data are presented with relevant tables and graphs to give a clear view of the market at first sight

The B-cell lymphomas market is driven by the rising global incidence of non-Hodgkin lymphomas, increasing adoption of targeted therapies like anti-CD20 antibodies and BTK inhibitors, and ongoing advances in immunotherapy and CAR T-cell treatments. Strong R&D investment and favorable regulatory pathways further support market growth. However, the market faces barriers such as high treatment costs, limited access in low- and middle-income countries, and the emergence of drug resistance. Additionally, long-term safety concerns and variability in patient response to therapies pose challenges. Despite these hurdles, the market continues to expand with a strong pipeline and evolving precision medicine strategies.

According to DelveInsight, the B-Cell Lymphomas market in 7MM is expected to witness a major change in the study period 2019-2032.

B-Cell Lymphomas Epidemiology
The B-Cell Lymphomas epidemiology section provides insights into the historical and current B-Cell Lymphomas patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the B-Cell Lymphomas market report also provides the diagnosed patient pool, trends, and assumptions.

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B-Cell Lymphomas Drugs Uptake
This section focuses on the uptake rate of the potential B-Cell Lymphomas drugs recently launched in the B-Cell Lymphomas market or expected to be launched in 2019-2032. The analysis covers the B-Cell Lymphomas market uptake by drugs, patient uptake by therapies, and sales of each drug.
B-Cell Lymphomas Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on B-Cell Lymphomas market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

B-Cell Lymphomas Pipeline Development Activities
The B-Cell Lymphomas report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses B-Cell Lymphomas key players involved in developing targeted therapeutics.

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B-Cell Lymphomas Therapeutics Assessment
Major key companies are working proactively in the B-Cell Lymphomas Therapeutics market to develop novel therapies which will drive the B-Cell Lymphomas treatment markets in the upcoming years are Oncternal Therapeutics, Inc., ZAI Lab, Pfizer, Xynomic Pharmaceuticals, SystImmune Inc., Autolus Limited, Vincerx Pharma, Ubix Therapeutics, Biomea Fusion Inc., Shanghai Hengrui Pharmaceutical, BeiGene, Hanmi Pharmaceutical, Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Merck Sharp & Dohme LLC, Sanofi, InnoCare Pharma, Allogene Therapeutics, Cellular Biomedicine Group Ltd., Genentech, Philogen, Aleta Biotherapeutics, Incyte Corporation, Fundamenta Therapeutics, Juventas Cell Therapy, Shanghai Hengrui Pharmaceutical Co., Guangzhou Lupeng Pharmaceutical, TG Therapeutics Inc., Roche, 2seventy bio, AstraZeneca, Nektar Therapeutics, ADC Therapeutics, Genor Biopharma, Pacylex Pharmaceuticals, Antengene Corporation, Zhejiang DTRM Biopharma, Shanghai Cell Therapy Group Co., Nanjing Legend Biotech Co. and others.

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B-Cell Lymphomas Report Key Insights
1. B-Cell Lymphomas Patient Population
2. B-Cell Lymphomas Market Size and Trends
3. Key Cross Competition in the B-Cell Lymphomas Market
4. B-Cell Lymphomas Market Dynamics (Key Drivers and Barriers)
5. B-Cell Lymphomas Market Opportunities
6. B-Cell Lymphomas Therapeutic Approaches
7. B-Cell Lymphomas Pipeline Analysis
8. B-Cell Lymphomas Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the B-Cell Lymphomas Market

Table of Contents
1. Key Insights
2. Executive Summary
3. B-Cell Lymphomas Competitive Intelligence Analysis
4. B-Cell Lymphomas Market Overview at a Glance
5. B-Cell Lymphomas Disease Background and Overview
6. B-Cell Lymphomas Patient Journey
7. B-Cell Lymphomas Epidemiology and Patient Population
8. B-Cell Lymphomas Treatment Algorithm, Current Treatment, and Medical Practices
9. B-Cell Lymphomas Unmet Needs
10. Key Endpoints of B-Cell Lymphomas Treatment
11. B-Cell Lymphomas Marketed Products
12. B-Cell Lymphomas Emerging Therapies
13. B-Cell Lymphomas Seven Major Market Analysis
14. Attribute Analysis
15. B-Cell Lymphomas Market Outlook (7 major markets)
16. B-Cell Lymphomas Access and Reimbursement Overview
17. KOL Views on the B-Cell Lymphomas Market
18. B-Cell Lymphomas Market Drivers
19. B-Cell Lymphomas Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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