Steady Expansion Forecast for In-Vitro Lung Model Market, Projected to Reach $1.16 Billion by 2029

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In-Vitro Lung Model Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
There has been a considerable expansion in the market size of the in-vitro lung model in the past few years. The market, which was worth $0.44 billion in 2024, is projected to escalate to $0.54 billion in 2025 with a compound annual growth rate (CAGR) of 21.3%. Factors contributing to the surge during the historic period include an increase in respiratory diseases, a heightened emphasis on personalized medicine, rising interest in drug re-purposing, focus on precise medical approaches and an increased consciousness about environmental health hazards.

In-Vitro Lung Model Market Size Forecast: What's the Projected Valuation by 2029?
The market size of the in-vitro lung model is projected to witness significant expansion in the coming few years, and is estimated to reach $1.16 billion by 2029, growing at a compound annual growth rate (CAGR) of 21.0%. This predicted growth during the forecast period may be due to the demand for drug development, an increase in preclinical testing, heightened awareness about respiratory toxicology, emphasis on regenerative medicine, increased environmental concerns, and the rise in the aging population. The forecast period also anticipates broader trends including heightened demand for drug testing, technological advancements in 3D printing, progressions in organ-on-chip technology, the incorporation of AI and machine learning, adaptation of sensors and monitoring devices, widening applications beyond pharmaceuticals, and the creation of disease-specific models.

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What Are the Drivers Transforming the In-Vitro Lung Model Market?
The upward trend in clinical studies is anticipated to fuel the expansion of the in vitro lung model market in the future. Clinical studies denote medical research trials that evaluate the effectiveness of novel medical techniques in human beings. The surge in clinical studies can be attributed to the increasing demand for sophisticated medical treatments, escalating healthcare needs, and the quest for inventive answers to intricate health challenges. In clinical trials, in vitro lung models serve a crucial role by offering a regulated setting to investigate the impacts of substances on lung tissue, assisting in drug testing, toxicity evaluation, disease simulation, and comprehension of disease processes. For instance, as reported by ClinicalTrials.gov, a clinical trial registry based in the US, by the conclusion of 2023, there were 477,230 globally registered clinical trials on ClinicalTrials.gov. This depicts a rise in comparison to 437,508 registered clinical trials in 2022. Consequently, the upsurge in clinical studies is fuelling the growth of the in vitro lung model market.

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What Long-Term Trends Will Define the Future of the In-Vitro Lung Model Market?
Leading corporations within the invitro lung model market are innovating by producing 3D respiratory tissue models, aiming to increase the physiological relevance and complexity of their models. These 3D models are developed by cultivating certain respiratory cells in a specific setting, enabling them to form a three-dimensional structure that simulates the function and morphology of the respiratory system. This approach provides a more relevant platform for research and drug trials. For example, in April 2023, US biotech firm MatTek Corporation unveiled EpiNasal, a cutting-edge 3D respiratory tissue model derived from primary human nasal epithelial cells. This model successfully duplicates the three-dimensional structure and function of nasal epithelium, including the production of mucus by goblet cells, the operation of tight junctions, and cilia movement. The launch of EpiNasal broadens MatTek's range of 3D respiratory tissue models, offering a robust system for exploring the impact of pharmaceuticals, chemicals, pathogens, and consumer goods on the human respiratory system.

Which Segments in the In-Vitro Lung Model Market Offer the Most Profit Potential?
The in-vitro lung model market covered in this report is segmented -

1) By Type: Two-Dimensional (2D) Model, Three-Dimensional (3D) Model
2) By Application: Drug Discovery And Toxicology Studies, Physiological Research, Three-Dimensional (3D) Model Development, Other Applications
3) By End-User: Academic Research Institutes, Pharmaceutical And Biotechnology Companies, Other End-Users

Subsegments:
1) By Two-Dimensional (2D) Model: Monolayer Cell Cultures, Co-cultures
2) By Three-Dimensional (3D) Model: Spheroids, Organoids, Lung-On-A-chip Models

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Which Firms Dominate the In-Vitro Lung Model Market by Market Share and Revenue in 2025?
Major companies operating in the in-vitro lung model market are Thermo Fisher Scientific Inc., Lonza Group AG, PerkinElmer Inc., Charles River Laboratories International Inc., Varian Medical Systems Inc., Epithelix, The Charles Stark Drape*r Laboratory Inc., STEMCELL Technologies, American Type Culture Collection (ATCC), BioIVT, InSphero, Emulate Inc., PhoenixBio Co. Ltd., Newcells Biotech, CN Bio Innovations Ltd., Mimetas, Cyfuse Biomedical K.K., 3D Biotek LLC, AlveoliX AG, AxoSim Technologies LLC, Elveflow, Hesperos Inc., Kugelmeiers Ag, SynVivo Inc., VITROCELL Systems GmbH

Which Regions Offer the Highest Growth Potential in the In-Vitro Lung Model Market?
North America was the largest region in the in-vitro lung model market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro lung model market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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