Capillary Electrophoresis Market Set for 5.2% CAGR Growth Through 2032, Says Persistence Market Research

Capillary electrophoresis (CE) has become a cornerstone in modern analytical laboratories, especially in areas like genomics, proteomics, pharmaceutical quality control, and forensic casework. This powerful technique offers high-resolution separations of biomolecules based on their size-to-charge ratios. As global demand for biotechnology, pharmacology, and genomics grows, the capillary electrophoresis market is expected to expand significantly. According to a report from Persistence Market Research, the capillary electrophoresis market is projected to reach US$ 560.7 million by 2032, growing from US$ 393.0 million in 2025, reflecting a compound annual growth rate (CAGR) of 5.2% during the forecast period from 2025 to 2032.

The technology's evolution over recent years has allowed for greater sensitivity, efficiency, and versatility, thus becoming an indispensable tool in various fields. Its ability to handle minute sample volumes while providing fast and reliable results makes it ideal for use in laboratories where accuracy and efficiency are crucial. Notably, the integration of capillary electrophoresis-mass spectrometry (CE-MS) and microfluidic CE chips have added new capabilities and applications to the technology, leading to a resurgence in its adoption.

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Key Highlights from the Report

➤ Global capillary electrophoresis market is projected to reach US$ 560.7 million by 2032.
➤ North America is expected to lead the market due to strong pharmaceutical and biotech industry presence.
➤ Nucleic acid analysis is set to capture 29.6% of the market share in 2025.
➤ Consumables will dominate, accounting for 70.4% of the market share in 2025.
➤ Collaboration between academic institutes and technology providers will spur innovations in CE.
➤ Forensics and paternity testing will continue to drive market growth.

Overview of the Capillary Electrophoresis Market

The capillary electrophoresis market has witnessed rapid advancements and is poised to continue its upward trajectory. The technology is central to several high-demand applications, such as drug development, diagnostics, and forensic analysis. Persistence Market Research's report shows that the market is expected to experience significant growth driven by key factors, including the increasing demand for biologics and biosimilars, the advancement of genomic and proteomic research, and the growing emphasis on precision medicine.

Key growth drivers for the CE market include the escalating demand for high-throughput, accurate diagnostics, particularly in genomics and clinical research. As industries such as pharmaceuticals, biotechnology, and forensics continue to evolve, the need for advanced analytical methods like CE has grown. Additionally, North America remains the leading geographical region for capillary electrophoresis due to the strong presence of pharmaceutical and biotech companies, as well as the region's established infrastructure for genomic research and forensic applications.

Market Segmentation

Capillary electrophoresis can be categorized based on several factors, including product types, applications, and end users. From a product perspective, the market is divided into instruments, consumables, and software. Of these, consumables are expected to dominate, as they represent a recurring operational need for CE runs. These consumables include buffers, capillaries, and reagents, all of which are required for each use, making them ideal for routine laboratory operations. Instruments, though higher in one-time purchase costs, are expected to see robust growth due to their central role in enabling CE processes across a wide array of applications.

From an application standpoint, the CE market is largely segmented into nucleic acid analysis, protein analysis, and various forms of genomic analysis. Nucleic acid analysis, in particular, is set to hold the largest share of the market, with applications in COVID-19 variant tracking and viral genotyping being key drivers. Protein analysis, especially in the form of monoclonal antibody (mAb) characterization, is also set to experience strong growth, driven by increased demand in biopharma and biologics development.

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Regional Insights

North America

North America is set to dominate the capillary electrophoresis market, accounting for approximately 35.7% of the market share in 2025. This dominance can be attributed to the region's well-established pharmaceutical manufacturing sector, its thriving genomics research ecosystem, and its strong forensic infrastructure. In particular, the U.S. Food and Drug Administration (FDA) and other regulatory bodies play a pivotal role in the adoption of CE in drug development and quality control. The U.S. is also home to numerous leading biotechnology firms and academic institutions that heavily invest in CE technologies for a variety of applications, including gene therapy and biosimilar analysis.

Europe

Europe is also a key player in the global capillary electrophoresis market, driven by the region's robust biopharmaceutical industry and a strong regulatory environment for pharmaceutical manufacturing. The European Medicines Agency (EMA) has stringent requirements for biologic characterization, often using CE as the gold standard for analyzing size and charge variants of biologics. Additionally, academic research initiatives such as those conducted by the Netherlands Proteomics Center are using CE-MS workflows for biomarker discovery in neurodegenerative diseases, which is spurring further demand.

Asia-Pacific

In the Asia-Pacific region, countries like China, South Korea, and Japan are showing increasing adoption of capillary electrophoresis systems. Particularly, China's biopharma sector is experiencing rapid growth, with companies like WuXi Biologics investing in CE for monoclonal antibody production. Furthermore, Japan is pioneering CE integrations with microfluidic technologies and mass spectrometry for clinical proteomics, with notable developments in neurodegenerative disease diagnostics. These advancements are making the Asia-Pacific region a key growth area for the market.

Market Drivers

Widespread Adoption in Paternity Testing and Diagnostics

Capillary electrophoresis has gained widespread use in paternity testing and clinical diagnostics, especially in the detection of genetic disorders such as sickle cell anemia and beta-thalassemia. The precise allele discrimination provided by fluorescently labeled Short Tandem Repeat (STR) markers has made CE the preferred method for DNA profiling. According to Persistence Market Research, more than 90% of accredited DNA testing labs worldwide use CE-based STR profiling, which is recognized for its accuracy and legal admissibility.

Demand for Advanced Biopharmaceuticals

As the demand for biologics and biosimilars grows, the need for advanced methods like capillary electrophoresis to characterize monoclonal antibodies (mAbs) and other biologics has increased. The regulatory requirements for mAb analysis, including charge variant and glycan profiling, have made CE a critical tool for both drug development and quality control.

Forensic and Trace Evidence Analysis

CE's ability to analyze trace evidence in forensics has opened new market opportunities. The technology is widely used for STR-based human identification and can also analyze minute quantities of synthetic fibers, inks, and dyes. Its increasing adoption by forensic labs worldwide is expected to drive market growth in this sector.

Market Restraints

Capillary Blockages and Maintenance Complexity

One of the primary challenges faced by capillary electrophoresis systems is the frequent capillary blockages caused by sample debris, aggregated proteins, or residual buffers. These issues can cause significant operational downtime and require extensive maintenance, including reconditioning protocols. As per a 2023 survey, over 40% of CE users reported that clogging was a key cause of workflow interruptions. This can also lead to high costs for capillary replacements and recalibrations, which restricts the widespread adoption of CE systems in certain settings.

High Initial Costs of Instruments

While consumables dominate in terms of market share, instruments remain a significant investment, particularly in regulated industries like biopharma. The initial cost of purchasing advanced CE systems can be a barrier for small and medium-sized laboratories, thus limiting broader market penetration in certain regions or applications.

Market Opportunities

New Applications in Forensics and Environmental Monitoring

The increasing integration of capillary electrophoresis with laser-induced fluorescence in forensic applications, such as document examination and ink dye analysis, presents a significant opportunity for the market. Additionally, the growing focus on environmental monitoring for pollutants and biomarker analysis in diseases like Alzheimer's offers further avenues for CE adoption in both clinical and non-clinical settings.

Integration with Microfluidics and Mass Spectrometry

The integration of capillary electrophoresis with microfluidic technologies and mass spectrometry is set to expand the application scope of CE. For instance, in proteomics and genomic research, this integration allows for higher throughput, increased sensitivity, and the ability to analyze complex samples, opening new doors for its use in precision medicine and diagnostic applications.

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Reasons to Buy the Report

✔ Comprehensive market analysis, including forecasts for the capillary electrophoresis market from 2025 to 2032.
✔ Detailed market segmentation based on product types, applications, and geographical regions.
✔ Insights into key market drivers, restraints, and opportunities for strategic planning.
✔ In-depth analysis of regional trends and growth prospects in North America, Europe, and Asia-Pacific.
✔ Profiles of leading players and recent industry developments to understand competitive dynamics.

Company Insights

✦ CBS Scientific
✦ Agilent Technologies Inc.
✦ Helena Laboratories
✦ Danaher Corporation
✦ Thermo Fisher Scientific Inc.
✦ QIAGEN
✦ PerkinElmer Inc.
✦ Bio-Rad Laboratories Inc.
✦ Shimadzu Corporation
✦ Bio-Techne Corporation
✦ Merck KGaA

Recent Developments

Thermo Fisher Scientific launched the Applied Biosystems SeqStudio Flex Dx Genetic Analyzer in March 2025, offering a compliant system for clinical and research purposes in Sanger sequencing.

Agilent Technologies Inc. unveiled the Agilent ProteoAnalyzer system in January 2024, a new automated platform designed for protein analysis, improving laboratory workflow efficiency.

The global capillary electrophoresis market is poised for substantial growth as technological advancements and increasing applications continue to drive its adoption across industries like biopharma, diagnostics, and forensics.

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