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2025-2034 In-Vitro Transcription Templates Market Outlook: Key Drivers, Emerging Challenges, and Strategic Insights

08-07-2025 07:18 AM CET | Health & Medicine

Press release from: The Business Research Company

In-Vitro Transcription Templates Market

In-Vitro Transcription Templates Market

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What Will the In-Vitro Transcription Templates Industry Market Size Be by 2025?
In recent times, the market size of in-vitro transcription templates has seen exponential growth. It is projected to increase from $1.01 billion in 2024 to about $1.25 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 23.7%. Multiple drivers have led to growth in the historic period, including the escalation in chronic disease conditions, increased allocation of funds in research and development within healthcare and pharmaceutical sectors, advances in gene therapy technology, strategic collaborations and partnerships, and progress in gene therapy development.

What's the Long-Term Growth Forecast for the In-Vitro Transcription Templates Market Size Through 2029?
The market size for in-vitro transcription templates is forecasted to experience a significant surge in the upcoming years, reaching a value of $2.9 billion in 2029 with a CAGR of 23.4%. The escalation during the projected period can be credited to improvements in biotechnology, amplified attention towards R&D pursuits, increased usage of in-vitro transcription templates, the urgency for early disease diagnosis, and a rising demand for mRNA-based vaccines. Novel developments in RNA synthesis techniques, advancements in technology and biotechnology, improvements in enzymatic synthesis methods, alongside the incorporation of automation and digitalization are key trends predicted to shape the industry in the forecast period.

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What Are the Key Growth Drivers Fueling the In-Vitro Transcription Templates Market Expansion?
The escalating attention towards gene therapy is projected to fuel the expansion of the in-vitro transcription templates market. Gene therapy consists of altering genes within cells with the aim of treating or averting diseases by mending flawed genes. The significant development in technologies such as CRISPR, substantial investments, and recent victorious treatments have augmented emphasis on this tactic. In-vitro transcription templates contribute to gene therapy by offering the RNA molecules that are critical for mRNA-based therapies, siRNA-based therapies, as well as gene editing technologies, making the treatment of genetic diseases and disorders possible. For example, in March 2024, the Food and Drug Administration (FDA), a United States federal agency of the Department of Health and Human Services projected that 36 gene therapies had been sanctioned by the FDA, with an extra 500 in the works, and forecasts that around 10-20 will be certified annually by 2025. Therefore, the amplified attention towards gene therapy is driving the expansion of the in-vitro transcription templates market.

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What Are the Key Trends Driving In-Vitro Transcription Templates Market Growth?
Key players in the in-vitro transcription templates market are progressing towards the development of self-amplifying RNA synthesis services. Such services aim to magnify the power of RNA-based treatments, ensure cost-effective production, and boost patient results across diverse therapeutic uses. Self-amplifying RNA synthesis is an advancing technology that facilitates the creation of self-replicating RNA within host cells, resulting in amplified protein expression from minimal RNA input and augmenting the competency of RNA-based therapies. An instance of this progress is the launch of a self-amplifying RNA (saRNA) synthesis service by GenScript Biotech Corporation, a US-based biotech company in May 2024. This service, part of its extended in vitro transcription RNA synthesis portfolio, boosts the effectiveness of vaccines, immunotherapies, and gene therapies by endorsing robust protein expression from minimal RNA. The saRNA platform anticipates reducing dosages, decreasing production expenses, and bettering patient results. Backed by thorough research and development, GenScript's saRNA boasts remarkable purity and augmented protein expression, ensuring dependable performance.

How Is the In-Vitro Transcription Templates Market Segmented?
The in-vitro transcription templates market covered in this report is segmented -

1) By Treatment: Vaccine, Therapeutic
2) By Research Stage: Exploratory, Clinical
3) By Disease: Cancer, Infectious Disease, Lifestyle Disease, Genetic Disease, Other Diseases
4) By End User: Pharmaceutical And Biotechnology Companies, Contract Research Organizations (CROs) And Contract Manufacturing Organizations (CMOs), Academics And Research, Other End Users

Subsegments:
1) By Vaccine: MRNA Vaccines, DNA Vaccines
2) By Therapeutic: Gene Therapy, RNA-Based Therapeutics

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Which Companies Are Leading the Charge in In-Vitro Transcription Templates Market Innovation?
Major companies operating in the in-vitro transcription templates market are Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Eurofins Genomics LLC, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., Qiagen N.V., Integrated DNA Technologies Inc., Promega Corporation, Genescript Biotech Corporation, Takara Bio Inc., New England Biolabs, OriGene Technologies Inc., Cayman Chemical, Synthego Corporation, Synbio Technologies, Creative Diagnostics, VectorBuilder Inc., Bio-Synthesis Inc., TriLink BioTechnologies, Norgen Biotek Corporation, Genaxxon BioScience GmbH, Enzo Life Sciences Inc., GeneCopoeia

Which Regions Are Leading the Global In-Vitro Transcription Templates Market in Revenue?
North America was the largest region in the in-vitro transcription templates market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro transcription templates market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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