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Gene Therapy on Cardiovascular Disease Market Exclusive Report on Current Trends and Future Insights
According to the latest research by InsightAce Analytic, the Global Gene Therapy on Cardiovascular Disease Market is predicted to grow with a CAGR of 67.4% during the forecast period of 2024-2031.
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Gene therapy for cardiovascular diseases involves the introduction of genetic material into a patient's cells to treat or prevent various heart-related conditions. A primary objective of this therapy, particularly in coronary artery disease, is to improve cardiac and vascular function by correcting genetic abnormalities or modulating gene expression. One prevalent method utilizes viral vectors to deliver therapeutic genes directly to cardiac or arterial cells. Clinical trials have demonstrated promising outcomes in addressing conditions such as heart failure and inherited cardiovascular disorders through gene therapy.
The growing interest from both public institutions and private stakeholders in the research and development of gene therapy underscores the market's potential for substantial expansion. A notable advancement in this field is the emergence of mRNA-based gene therapies. Unlike traditional methods, which transfer therapeutic genes directly to the target cells, mRNA-based therapies deliver synthetic messenger RNA (mRNA) that encodes the desired therapeutic protein. Once inside the target cells, the mRNA serves as a template for protein production, offering several advantages, including enhanced safety profiles, reduced production complexity, and cost-efficiency.
List of Prominent Players in the Gene Therapy on Cardiovascular Disease Market:
• Biogen
• Novartis
• Gilead Sciences
• Sarepta Therapeutics
• Alnylam Pharmaceuticals
• Amgen
• Spark Therapeutics
• Akcea Therapeutics
• Sunway Biotech
• bluebird bio
• SIBIONO
• AnGes
• Orchard Therapeutics
• Other Market Players
Market Dynamics:
Drivers-
The increasing demand for gene therapy in the cardiovascular disease sector is primarily driven by the rising prevalence of chronic illnesses, including various cancers and rare genetic disorders. A growing number of individuals are recognizing gene therapy as a viable and promising treatment option, particularly for oncological and hereditary conditions. Furthermore, the expanding support from government bodies through funding initiatives and favorable regulatory frameworks is contributing significantly to the advancement and adoption of gene therapy, thereby accelerating market growth.
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Challenges:
Despite its potential, the cardiovascular gene therapy market faces several key challenges. High development and operational costs remain a significant barrier, particularly in regions with limited healthcare funding. The advanced nature of gene therapy necessitates substantial investment in research, development, and skilled human resources-factors that are often constrained in emerging economies. The lack of standardized reimbursement protocols and limited insurance coverage further restrict patient access to these therapies, especially for those without adequate financial means. Uncertainty around the long-term efficacy and safety of gene therapies also leads to reluctance among insurers and healthcare providers to fully support these treatments.
Regional Trends:
North America is expected to command a significant share of the gene therapy market for cardiovascular diseases, driven by the high incidence of cardiovascular conditions, robust R&D investments, and increasing adoption of advanced medical technologies. Favorable government initiatives and rising healthcare expenditure further support the region's market growth. Meanwhile, Europe holds a substantial portion of the market due to a broad patient base, increased public awareness of gene therapy, a surge in cancer incidence, and strong engagement in research and innovation activities.
Recent Developments:
• In Nov 2023, Amgen presented new information at the American Heart Association (AHA) Scientific Sessions 2023 in Philadelphia, which further supports the safety and effectiveness of Repatha® (evolocumab) based on the FOURIER Open Label Extension (OLE) [FOURIER-OLE] trial. The presentations will specifically address the reduction of LDL "bad" cholesterol (LDL-C), which is a well-known risk factor for cardiovascular disease (CVD).
• In Aug 2023, Lexeo Therapeutics received a strategic investment from Sarepta Therapeutics to aid in the advancement of Lexeo's cardiovascular gene therapies. The companies will investigate the creation of innovative gene therapy candidates for various cardiovascular diseases as part of this investment.
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Segmentation of Gene Therapy on Cardiovascular Disease Market-
By Type-
• Viral Gene Therapy
• Non-Viral Gene Therapy
By Application-
• Heart Disease
• Vascular Disease
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain a competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets, and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.https://www.insightaceanalytic.com/images_data/148861653.
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