Key Factor Supporting Biobetters Market Development in 2025: Impact Of Chronic Kidney Disease On The Biobetters Market

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How Large Will the Biobetters Market Size By 2025?
The size of the biobetters market has witnessed quick expansion in the past few years. It is expected to increase from a value of $67.81 billion in 2024 to reach around $75.98 billion in 2025, showcasing a compound annual growth rate (CAGR) of 12.0%. Factors contributing to this growth during the historical period include a deeper grasp of disease mechanisms, a rise in spending on healthcare, improvements in manufacturing technologies, breakthroughs in drug delivery technology, advancements in protein engineering, and a heightened demand for enhanced therapeutic efficacy.

How Big Is the Biobetters Market Size Expected to Grow by 2029?
In the coming years, the market size for biobetters is anticipated to experience swift expansion. By 2029, it is projected that it will attain a value of $118.2 billion, with an 11.7% compound annual growth rate (CAGR). The forecasted growth is primarily due to progress in biotechnology, increasing emphasis on individualized medicine, the broadening pipeline of biopharmaceutical firms, escalating incidence of chronic illnesses, conducive regulations, increased R&D investments, and improved healthcare infrastructure. The anticipated trends for the forecast period encompass the creation of new biobetters, protein engineering and rational design, focus on therapeutic domains, progressive healthcare infrastructure, emergence of next-generation sequencing (NGS) technologies and advancements in high-throughput screening (HTS) technologies.

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Which Key Market Drivers Powering Biobetters Market Expansion and Growth?
The biobetters market is anticipated to expand due to the escalating number of chronic kidney diseases. Over time, these illnesses degrade kidney function until it eventually ceases. Their growing occurrence is attributed to the aging populace, prevalent cases of hypertension and diabetes, unhealthy diet, lack of physical activities, environmental pollutants, and improved diagnosis techniques. Biobetters contribute to managing chronic kidney diseases by providing superior effectiveness, minimising side effects, offering better dosage routines, and enhancing stability against conventional biological treatments, hence improving patient results. For instance, by June 2023, the Oxford Academic, a research platform of Oxford University Press in the UK, predicts the number of CKD cases in the UK will increase by 4% from 8.27 million to 8.61 million individuals from 2022 to 2032, with the stage distribution in 2032 anticipated at 30.36% for stage 1, 21.07% for stage 2, 29.78% for stage 3a, 11.86% for stage 3b, 4.15% for stage 4, and 2.78% for stage 5. Consequently, the escalating number of chronic kidney diseases is catalysing the biobetters market expansion. Biobetters Market Driver: Effect Of Autoimmune Diseases On The Biobetters Market

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Which Fast-Growing Trends Are Poised to Disrupt the Biobetters Market?
Notable players in the biobetters industry are focusing their efforts on creating biobetters intended for subcutaneous administration. This is aimed at enhancing the comfort level of patients, improving the results of therapy, and minimizing costs related to healthcare. The method of administering biobetters subcutaneously provides a more user-friendly option compared to intravenous infusion and may boost patient adherence and the effectiveness of healthcare delivery. As an example, in May 2023, Celltrion, a biopharmaceutical firm based in South Korea, obtained authorization from the Brazilian Health Regulatory Agency for their Remsima SC biobetters. This innovative biobetter is an advanced version of their infliximab biosimilar, known as Remsima, and it's the only infliximab worldwide that offers subcutaneous administration. Remisma SC amplifies a biosimilar's reach and efficiency. It has a specific indication for inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. For patients, Remisma SC is an opportunity for a more comfortable and potentially more effective mode of treatment.

What Are the Emerging Segments in the Biobetters Market?
The biobetters market covered in this report is segmented -

1) By Drug Class: Erythropoietin Biobetters, Granulocyte-Colony Stimulating Factor (G-CSF) Bioreactors, Interferon Biobetters, Insulin Biobetters, Monoclonal Antibodies Biobetters, Antihemophilic Factors, Other Drug Classes
2) By Route Of Administration: Oral, Subcutaneous, Inhaled, Intravenous, Other Routes
3) By Disease Indication: Diabetes, Cancer, Renal Disease, Neurodegenerative Diseases, Genetic Disorder-Hemophilia, Other Diseases
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:
1) By Erythropoietin Biobetters: Darbepoetin Alfa, Continuous Erythropoietin Receptor Activator (CERA)
2) By Granulocyte-Colony Stimulating Factor (G-CSF) Biobetters: Pegfilgrastim, Lipegfilgrastim
3) By Interferon Biobetters: Pegylated Interferon Alfa-2a, Pegylated Interferon Alfa-2b
4) By Insulin Biobetters: Long-Acting Insulin Analogs (Insulin Glargine), Rapid-Acting Insulin Analogs (Insulin Aspart)
5) By Monoclonal Antibodies Biobetters: Trastuzumab (Herceptin Biosimilars), Bevacizumab (Avastin Biosimilars), Rituximab (Rituxan Biosimilars)
6) By Antihemophilic Factors: Recombinant Factor VIII (Nuwiq), Recombinant Factor IX (Alprolix)
7) By Other Drug Classes: Growth Factors, Cytokines, Enzyme Replacement Therapies, Vaccines

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Who Are the Global Leaders in the Biobetters Market?
Major companies operating in the biobetters market are Pfizer Inc., Johnson & Johnson, Merck & Co Inc., AbbVie Inc., Bayer AG, Sanofi Aventis LLC, Bristol-Myers Squibb Company, Novartis AG, GlaxoSmithKline plc, F Hoffmann La Roche Ltd., Eli Lilly and Co Ltd., Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Regeneron Pharmaceuticals Inc., CSL Behring GmbH, Biogen Inc., GRIFOLS USA LLC, Celltrion Inc., Lonza Group AG, Ionis Pharmaceuticals Inc., Incyte Corporation, Amicus Therapeutics Inc., Genentech Inc., Sun Pharmaceutical Industries

Which are the Top Profitable Regional Markets for the Biobetters Industry?
North America was the largest region in the biobetters market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the biobetters market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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