Protein Expression Market Exclusive Report with Detailed Study Analysis

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Protein Expression Market"-, By Type of Protein Expression System (Algal, Cell-free, Insect, Mammalian, Prokaryotic and Yeast), Protein Expression-related Offerings (Competent Cells, Expression Vectors, Instruments, Kits and Reagents, and Protein Expression Services), Application Area (Research and Diagnostics, and Therapeutics), End-users (Academic and Research Institutes, CROs and CDMOs, Pharmaceutical / Biotechnology Companies, and Other End-users), Type of Operation (In-house and Outsourced Operations), Industry Trends, and Global Forecasts, 2024-2031 And Segment Revenue and Forecast To 2031."

The Protein Expression Market Size is valued at USD 2.5 Bn in 2023 and is predicted to reach USD 4.6 Bn by the year 2031 at an 7.7% CAGR during the forecast period for 2024-2031.

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Protein expression refers to the biological process through which proteins are synthesized, regulated, and modified within living organisms. This process relies on various components, including competent cells, chemicals, specialized tools, services, and expression vectors. Among these, reagents are anticipated to hold the largest market share, given their extensive use in bio-experiments. The protein expression market is poised for significant growth, driven by increased funding from governmental and non-governmental organizations for protein research, the rising prevalence of chronic diseases, and the expansion of the life sciences sector. Additionally, the growing demand for protein biologics and the increasing incidence of chronic disorders are expected to further accelerate market expansion over the forecast period.

The emergence of contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) has provided companies with opportunities to outsource protein production, allowing them to allocate resources to other areas of research and development. Advances in expression systems, including plant-based and yeast-based systems, are introducing more sustainable and efficient approaches for producing complex proteins.

List of Prominent Players in the Protein Expression Market:
• Agilent Technologies
• Ajinomoto Bio-Pharma Services
• Aldevron
• ARTES Biotechnology GmbH
• Bio-Rad Laboratories
• BIONEER CORPORATION
• Cayman Chemical
• Charles River Laboratories
• CORNING INCORPORATED
• Domainex
• DANAHER CORPORATION
• Eurofins CALIXAR
• FUJIFILM IRVINE SCIENTIFIC, INC.
• GeNext Genomics
• GenScript Biotech
• Lonza
• Lucigen Corporation
• LifeSensors Inc
• LEADING BIOLOGY, INC.
• Merck KGaA
• New England Biolabs
• Oxford Expression Technologies
• ProMab
• Promega
• ProteoGenix
• Peak Proteins Ltd
• QIAGEN
• Sartorius
• Synbio Technologies
• Syngene
• Synthetic Genomics Inc
• Sino Biological Inc
• JENA BIOSCIENCE
• Takara Bio
• Thermo Fisher Scientific
• WuXi Biologics

Market Dynamics:
Drivers:
The increasing adoption of biologics, including therapeutic proteins, monoclonal antibodies, and vaccines, for the treatment of cancer, autoimmune diseases, and chronic conditions is a key factor driving the market. Unlike traditional small-molecule drugs, biologics require advanced protein expression systems to facilitate their development and production. The rapid expansion of the biotechnology and pharmaceutical sectors, driven by advancements in drug discovery, personalized medicine, and therapeutic proteins, is further fueling demand for innovative protein expression technologies.

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Challenges:
The production of complex proteins, particularly those requiring post-translational modifications such as glycosylation, presents significant challenges. Prokaryotic expression systems, such as E. coli, often lack the capability to generate properly folded or modified proteins, necessitating the use of more sophisticated and cost-intensive platforms, such as mammalian cell-based systems, which can increase overall production costs.

Regional Trends:
North America, particularly the United States, holds the largest market share due to its well-established biotechnology and pharmaceutical industries, extensive research and development (R&D) initiatives, and substantial healthcare expenditure. The rising prevalence of chronic diseases, including cancer and autoimmune disorders, has heightened demand for therapeutic proteins such as monoclonal antibodies and vaccines.

Meanwhile, the Asia-Pacific region is experiencing the fastest growth in the protein expression market, driven by increased investments in biotechnology, expansion of pharmaceutical industries, and rising healthcare needs. The region is emerging as a key hub for outsourcing protein expression and biopharmaceutical production, owing to lower operational costs and the availability of skilled labor.

Recent Developments:
• In June 2024, HERCULES, Calif.,Bio-Rad Laboratories, Inc. The launch of the ddSEQTM Single-Cell 3' RNA-Seq Kit and corresponding Omnition v1.1 analysis software for single-cell transcriptome and gene expression research was announced by a global leader in life science research and clinical diagnostics products.
• In April 2023, Eurofins CALIXAR, declared the purchase of CALIXAR, a pioneer in providing the best membrane proteins for the life sciences. The purchase strengthens Eurofins Discovery and Eurofins DiscoverX®'s scientific leadership in G Protein-Coupled Receptors (GPCRs) and ion channels and provides critical capabilities in membrane protein synthesis of highly druggable targets. Gaining more knowledge in these crucial fields enhances the business's Biophysics and Biotherapeutics platforms, as well as its Integrated Drug Discovery platform, DiscoveryOneTM.
• In March 20022, ProteoGenix, declares the release of its transient expression system, XtenCHOTM. In comparison to previous methods, the novel patented mammalian cell-based expression host produces up to ten times higher yields with less hands-on time because of its optimised metabolism and enhanced plasmid stability. The novel CHO host seeks to expedite early phase drug screening and streamline the manufacture of recombinant proteins.

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Segmentation of Protein Expression Market.
Global Protein Expression Market- By Type of Protein Expression System
• Algal Expression Systems
• Cell-free Expression Systems
• Insect Expression Systems
• Mammalian Expression Systems
• Prokaryotic Expression Systems
• Yeast Expression Systems
Global Protein Expression Market - Protein Expression-related Offerings
• Competent Cells
• Expression Vectors
• Instruments
• Kits and Reagents
• Protein Expression Services
Global Protein Expression Market - By Application
• Research and Diagnostics
• Therapeutics
Global Protein Expression Market - By End user
• Academic and Research Institutes
• CROs and CDMOs
• Pharmaceutical and Biotechnology Companies
• Other End-users
• Type of Operation
• In-house Operations
• Outsourced Operations

Global Protein Expression Market - Type of Operation
• In-house Operations
• Outsourced Operations
Global Protein Expression Market - By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• Southeast Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa

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