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Steady Expansion Forecast for Endotoxin Testing Market, Projected to Reach $2.91 Billion by 2029

07-28-2025 12:19 PM CET | Health & Medicine

Press release from: The Business Research Company

Endotoxin Testing

Endotoxin Testing

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Endotoxin Testing Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
The market size for endotoxin testing has experienced consistent growth in the past few years. The market is forecasted to grow from $2.24 billion in 2024 to approximately $2.32 billion in 2025, with a compound annual growth rate (CAGR) of 3.6%. Factors contributing to the growth during the historical period include the rising demand for biologics and biosimilars, increased awareness regarding the significance of endotoxin testing, and a growing incidence of infectious diseases.

Endotoxin Testing Market Size Forecast: What's the Projected Valuation by 2029?
The market size for endotoxin testing is predicted to experience substantial expansion in the coming years. The predicted growth rate is set to reach $2.91 billion by 2029, with a compound annual growth rate (CAGR) of 5.8%. This growth during the projected period is attributed to factors such as biopharmaceutical industry expansion, increasing investment in endotoxin testing research and development, and expansion of global healthcare. Main trends during this period are predicted to include innovative tools for detecting endotoxins, the adoption of endotoxin testing services, and an increased demand for such services.

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What Are the Drivers Transforming the Endotoxin Testing Market?
The upward trend in healthcare-associated infections is anticipated to fuel the expansion of the endotoxin testing market. Healthcare-associated infections are those which are contracted during medical treatment but were absent during the patient's admission to the hospital. Such infections typically emerge from infected medical devices or protocols, necessitating a high level of testing to uphold patient safety. Endotoxin testing services play a pivotal role in mitigating healthcare-associated infections by evaluating the bacterial endotoxin levels in medical equipment, chiefly in injectable pharmaceutical products and implantable medical devices. For instance, UNICEF reported in December 2022 that pneumonia, an infectious disease, had the highest child mortality rate, claiming over 700,000 lives yearly, which translates to roughly 2,000 per day. As per the World Health Organization's report in May 2022, healthcare-associated sepsis impacts 24% of patients each year, plus, 52.3% of these patients, if treated in an ICU, succumbs each year. Therefore, the growing incidences of healthcare-associated infections are propelling the expansion of the endotoxin testing market. A rising demand for biologics to conduct numerous tests is projected to stimulate the endotoxin testing market's growth. Biologics or biologic products, also known as biopharmaceuticals, are pharmaceuticals formulated from living organisms, cells, or biological processes. Endotoxin testing is crucial for biologics to ascertain their safety, quality, and adherence to regulatory norms. As per a report from the European Pharmaceutical Review in May 2022, sales of biologics are predicted to vastly outstrip sales of ground-breaking small molecules over the next five years, signaling an estimated $120 billion surge in sales by 2027. This denotes a considerable shift in the pharmaceutical market towards biologic products. Therefore, the increasing demand for biologics to conduct various tests is escalating the growth of the endotoxin testing market.

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What Long-Term Trends Will Define the Future of the Endotoxin Testing Market?
In an attempt to maintain their market presence, predominant businesses in the endotoxin testing market are concentrating on the implementation of novel technological solutions. An example of this is Lonza Group AG, a pharmaceutical, biotechnology, and nutrition production entity based in Switzerland. The company, in August 2023, unveiled a new absorbance microplate reader for simplified endotoxin and pyrogen testing named the Nebula Absorbance Reader. This latest instrument is tightly integrated with Lonza's recent WinKQCL software to ensure data integrity compliance, hasten training, and lessen validation stress. The introduction of this advanced reader eliminates the need for users of WinKQCL software to understand new software, thus lessening training obligations. The Nebula Absorbance Reader serves as a modern, technologically sophisticated replacement reader that delivers results that are commonly seen with the ELx808 - a standard absorbance reader that Lorenz no longer offers. Moreover, it is created to be in line with and meet the demanding standards of Lonza's absorbance-based endotoxin assays, this includes the Lonza PYROGENT 5000 Turbidimetric and Kinetic-QCL Chromogenic Endotoxin Assays.

Which Segments in the Endotoxin Testing Market Offer the Most Profit Potential?
The endotoxin testing market covered in this report is segmented -

1) By Test Type: LAL (Limulus Amebocyte Lysate) Test, Chromogenic Tests, Turbidimetric Tests, Gel Clot Tests, MAT Test, Rabbit Pyrogen Test, Recombinant Factor C (rFC) Assay
2) By Application: Medical Devices, Pharmaceuticals, Packaging, Raw Materials
3) By End-User: Hospitals, Laboratories, Research Institutes

Subsegments:
1) By LAL (Limulus Amebocyte Lysate) Test: Gel Clot LAL Test, Kinetic LAL Test, Endpoint LAL Test
2) By Chromogenic Tests: Chromogenic LAL Test, Chromogenic Factor C Assay
3) By Turbidimetric Tests: Turbidimetric LAL Test, Turbidimetric Factor C Assay
4) By Gel Clot Tests: Gel Clot LAL Test
5) By MAT Test (Monocyte Activation Test): Direct MAT, Indirect MAT
6) By Rabbit Pyrogen Test: Standard Rabbit Pyrogen Test
7) By Recombinant Factor C (rFC) Assay: RFC Assay For Endotoxin Detection

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Which Firms Dominate the Endotoxin Testing Market by Market Share and Revenue in 2025?
Major companies operating in the endotoxin testing market are Thermo Fisher Scientific Inc., Merck KGaA, bioMérieux SA., Eurofins Scientific SE, Lonza Group Ltd., WuXi AppTec Co. Ltd., Bio-Rad Laboratories Inc., Maravai LifeSciences Holdings Inc., Cambrex Corporation, GenScript Biotech Corporation, Charles River Laboratories International Inc., Nelson Laboratories LLC, Lifecore Biomedical Inc., Stellar Biotechnologies Inc., Biovision Inc., Associates of Cape Cod Inc., FUJIFILM Wako Pure Chemical Corporation, InvivoGen Inc., Tebu-bio Nv., MatTek Corporation, Microcoat Biotechnologie GmbH, Accelagen Inc., BioAssay Systems LLC, BioThema AB, Hycult Biotech Inc., Pacific Biolabs Inc., Xiamen Bioendo Technology Co. Ltd., Zhanjiang A&C Biological Ltd., Accugen Laboratories Inc.

Which Regions Offer the Highest Growth Potential in the Endotoxin Testing Market?
North America was the largest region in the endotoxin testing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in endotoxin testing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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