Press release
5-HT2 Agonist Clinical Trials 2025: EMA, PDMA, FDA Approvals, Medication, Therapies, Treatment Market, Mechanism of Action, Route of Administration, and Companies by DelveInsight
5-HT2 agonist companies such as Cybin, Reunion Neuroscience, BetterLife Pharma, Gilgamesh Pharmaceuticals, Harmony Biosciences, Mindmed, ATAI LIFE SCIENCES N.V, Reviva Pharmaceuticals, Beckley Psytech, MindBio Therapeutics and others.(Albany, USA) DelveInsight's '5-HT2 Agonist Pipeline Insight 2025' report provides comprehensive global coverage of pipeline 5-HT2 agonists in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the 5-HT2 agonist pipeline domain.
Advancements in precision medicine drive the 5-HT2 agonist market by enabling selective targeting of specific receptor subtypes (e.g., 5-HT2A or 5-HT2C), reducing side effects and improving safety. Personalized approaches, like pharmacogenomics, identify patients most likely to benefit, enhancing treatment efficacy and adoption while accelerating drug development with cutting-edge technologies.
Download sample report to know more about 5-HT2 Agonist Clinical Trial @ 5-HT2 Agonist Pipeline Insight [https://www.delveinsight.com/report-store/5-ht2-agonist-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=apr]
Key Takeaways from the 5-HT2 Agonist Pipeline Report
* DelveInsight's 5-HT2 agonist pipeline report depicts a robust space with 20+ active players working to develop 22+ pipeline 5-HT2 agonists.
* Key 5-HT2 agonist companies such as Cybin, Reunion Neuroscience, BetterLife Pharma, Gilgamesh Pharmaceuticals, Harmony Biosciences, Mindmed, ATAI LIFE SCIENCES N.V, Reviva Pharmaceuticals, Beckley Psytech, MindBio Therapeutics and others are evaluating new 5-HT2 agonist drugs to improve the treatment landscape.
* Promising pipeline 5-HT2 agonists such as CYB003, RE104, BETR-001, GM2505, EPX-100, MM120, EMP 01, Brilaroxazine, Psilocybin infusion, MB-22001, and others are under different phases of 5-HT2 agonist clinical trials.
* In December 2024, Mind Medicine announced that MM120 ODT, a pharmaceutically optimized form of lysergide D-tartrate (LSD), had been granted an Innovation Passport for the potential treatment of GAD under ILAP by the U.K. Medicines and Healthcare products Regulatory Agency (MHRA).
* In October 2024, Lundbeck A/S and Longboard Pharmaceuticals, Inc. announced an agreement for Lundbeck to acquire Longboard. Under the terms of the agreement, Lundbeck will commence a tender offer for all outstanding shares of Longboard common stock, whereby Longboard shareholders will be offered a payment of USD 60.00 per share in cash.
* In October 2024, Bright Minds Biosciences Inc. a pioneering company focused on developing highly selective 5-HT2 agonists for the treatment of drug-resistant epilepsy, depression, and other CNS disorders, announced positive data from the preclinical testing of BMB-201 completed with National Institute of Health pain screening (PSPP) program.
* In March 2024, Mind Medicine announced that FDA has granted breakthrough designation to its MM120 (lysergide d-tartrate) program for the treatment of generalized anxiety disorder (GAD). the company also announced that its Phase 2b study of MM120 in GAD met its key secondary endpoint, and 12-week topline data demonstrated clinically and statistically significant durability of activity observed through Week 12.
Request a sample and discover the recent advances in 5-HT2 agonist drugs @ 5-HT2 Agonist Pipeline Report [https://www.delveinsight.com/sample-request/5-ht2-agonist-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=apr]
The 5-HT2 agonist pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage 5-HT2 agonist drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the 5-HT2 agonist clinical trial landscape.
5-HT2 Agonist Overview
5-HT2 (5-hydroxytryptamine 2) agonists are a class of drugs that selectively activate 5-HT2 receptors, a subgroup of serotonin receptors located in the central nervous system. Serotonin also referred to as 5-hydroxytryptamine (5-HT), is a neurotransmitter that plays a critical role in regulating mood, cognition, and sensory processing. The 5-HT2 receptor family includes three main subtypes: 5-HT2A, 5-HT2B, and 5-HT2C.
By binding to and stimulating these receptors, 5-HT2 agonists initiate a series of intracellular signaling cascades. These receptors, which are G protein-coupled receptors (GPCRs), influence key signaling pathways such as phospholipase C (PLC), protein kinase C (PKC), and mitogen-activated protein kinase (MAPK). As integral membrane proteins with seven transmembrane domains, 5-HT2 receptors mediate serotonin's effects by facilitating ligand binding, G protein coupling, and activation of downstream signaling, resulting in a variety of physiological and pharmacological outcomes. Understanding these mechanisms is crucial for developing therapeutic drugs targeting 5-HT2 receptors and for exploring their roles in health and disease.
Therapeutic targeting of 5-HT2 receptors has shown promise in several medical fields due to their significant role in regulating physiological processes. In psychiatry, 5-HT2A agonists have demonstrated potential as treatments for depression and anxiety, with compounds like psilocybin (from psychedelic mushrooms) and lysergic acid diethylamide (LSD) showing efficacy in controlled clinical settings. Similarly, 5-HT2C agonists are being investigated for their ability to manage obesity and metabolic disorders by modulating appetite and energy balance. In neurology, 5-HT2B and 5-HT2C agonists are being studied for their vasoconstrictive effects in migraine management, while 5-HT2B agonists are also under exploration for their cardioprotective benefits in conditions such as heart failure.
Despite their potential, the clinical application of 5-HT2 agonists requires careful consideration of their psychotropic effects and possible side effects. This highlights the need for rigorous research and controlled usage to optimize their therapeutic advantages.
Find out more about 5-HT2 agonist drugs @ 5-HT2 Agonist Pipeline Analysis [https://www.delveinsight.com/report-store/5-ht2-agonist-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=apr]
A snapshot of the Pipeline 5-HT2 Agonist Drugs mentioned in the report:
* CYB003: Cybin (Major depressive disorder)
* MM120 : MindMed/The University Hospital of Basel (Anxiety disorders)
* RE104: Reunion Neuroscience (Postnatal depression)
* GM2505: Gilgamesh Pharmaceuticals (Major depressive disorder)
* EPX-100: Epygenix Therapeutics/University of California at San Fransisco (Dravet syndrome; Lennox-Gastaut syndrome)
* BETR-001: BetterLife Pharma (Cluster headache; Major depressive disorder; Neuropathic pain; Post-traumatic stress disorders)
Learn more about the emerging 5-HT2 agonist @ 5-HT2 Agonist Clinical Trials and FDA Approvals [https://www.delveinsight.com/sample-request/5-ht2-agonist-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=apr]
5-HT2 Agonist Therapeutics Assessment
The 5-HT2 agonist pipeline report proffers an integral view of the emerging 5-HT2 agonist segmented by stage, product type, molecule type, and route of administration.
Scope of the 5-HT2 Agonist Pipeline Report
* Coverage: Global
* Therapeutic Assessment By Product Type: Mono, Combination, Mono/Combination
* Therapeutic Assessment By Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
* Therapeutics Assessment By Route of Administration: Intra-articular, Intraocular, Intrathecal, Intravenous, Oral, Parenteral, Subcutaneous, Topical, Transdermal
* Therapeutics Assessment By Molecule Type: Oligonucleotide, Peptide, Small molecule
* Key 5-HT2 Agonist Companies: Cybin, Reunion Neuroscience, BetterLife Pharma, Gilgamesh Pharmaceuticals, Harmony Biosciences, Mindmed, ATAI LIFE SCIENCES N.V, Reviva Pharmaceuticals, Beckley Psytech, MindBio Therapeutics and others,
* Key 5-HT2 Agonist Pipeline Therapies: CYB003, RE104, BETR-001, GM2505, EPX-100, MM120, EMP 01, Brilaroxazine, Psilocybin infusion, MB-22001 and others.
Dive deep into rich insights for new 5-HT2 agonists, visit @ 5-HT2 Agonist Drugs and Medication [https://www.delveinsight.com/sample-request/5-ht2-agonist-pipeline-insight?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=apr]
Table of Contents
1. 5-HT2 Agonist Pipeline Report Introduction
2. 5-HT2 Agonist Pipeline Report Executive Summary
3. 5-HT2 Agonist Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. 5-HT2 Agonist Clinical Trial Therapeutics
6. 5-HT2 Agonist Pipeline: Late-Stage Products (Pre-registration)
7. 5-HT2 Agonist Pipeline: Late-Stage Products (Phase III)
8. 5-HT2 Agonist Pipeline: Mid-Stage Products (Phase II)
9. 5-HT2 Agonist Pipeline: Early-Stage Products (Phase I)
10. 5-HT2 Agonist Pipeline Therapeutics Assessment
11. Inactive Products in the 5-HT2 Agonist Pipeline
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key Companies
14. Key Products in the 5-HT2 Agonist Pipeline
15. Unmet Needs
16. Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email:Send Email [https://www.abnewswire.com/email_contact_us.php?pr=5ht2-agonist-clinical-trials-2025-ema-pdma-fda-approvals-medication-therapies-treatment-market-mechanism-of-action-route-of-administration-and-companies-by-delveinsight]
Phone: +19193216187
Address:304 S. Jones Blvd #2432
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/consulting
Legal Disclaimer: Information contained on this page is provided by an independent third-party content provider. ABNewswire makes no warranties or responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you are affiliated with this article or have any complaints or copyright issues related to this article and would like it to be removed, please contact retract@swscontact.com
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release 5-HT2 Agonist Clinical Trials 2025: EMA, PDMA, FDA Approvals, Medication, Therapies, Treatment Market, Mechanism of Action, Route of Administration, and Companies by DelveInsight here
News-ID: 4114050 • Views: …
More Releases from ABNewswire

Unveiling the True Origins of the Great Flood by Tony Hughes Receives Critical A …
Author and independent researcher Tony Hughes has made a powerful debut with his newly released book, Unveiling the True Origins of the Great Flood: A Hypothesis - An Ice Meteor's Impact and its Ramifications on Earth's History [https://www.amazon.com/Unveiling-True-Origins-Great-Flood/dp/B0F88TNPXJ]. Since its release in May 2025, the book has rapidly garnered national, and even international, attention for its reevaluation of one of the world's most enduring legends: the Great Flood.
Hughes proposes that…

Redefined Restoration Delivers Rapid, Reliable Water Damage Restoration Service …
Redefined Restoration has become a standout name in Chicago's water damage recovery sector by providing a level of speed and reliability that homeowners and businesses increasingly demand.
Redefined Restoration has become a standout name in Chicago's water damage recovery sector by providing a level of speed and reliability that homeowners and businesses increasingly demand. Fast, professional response in the aftermath of water intrusion is crucial in preventing widespread damage and reducing…

Chicago's Redefined Restoration Delivers Advanced Water Remediation Solutions
Redefined Restoration has emerged as a leader in advanced water remediation, combining experience, technology, and a client-centered approach to provide peace of mind throughout the Chicago area.
Water damage is a persistent challenge facing Chicago's property owners, whether caused by severe storms, plumbing failures, or sudden accidental floods. Fast and thorough response is not just about salvaging possessions-it's essential for protecting the structural integrity and safety of buildings. Recognizing the urgency…

Industry Spotlight: Redefined Restoration Emerges as Chicago's Go-To Water Damag …
In a field crowded with providers, Redefined Restoration is beginning to stand out as the go-to choice for reliable and effective water damage solutions, responding with professionalism and modern expertise that sets a new industry benchmark.
Chicago, a bustling metropolis bordering Lake Michigan, is no stranger to water-related disasters. From sudden floods caused by heavy storms to accidental pipe bursts in historic buildings, the city's diverse properties remain vulnerable to water…
More Releases for Agonist
Opioids Agonist Drugs Market Size Unlocking New Opportunities for Success
In 2024, the global MDS treatment market was valued at approximately USD 2.87 billion. It is projected to reach around USD 5.95 billion by 2033, growing at a compound annual growth rate (CAGR) of 8.4% from 2025 to 2033.
Opioids Agonist Drugs Market Overview
Opioid agonist drugs act on opioid receptors in the central and peripheral nervous system and are primarily used for pain relief. The market includes natural, semi-synthetic, and…
Surging Diabetes Cases Fuel Growth In Glp-1 Receptor Agonist Market: Key Factor …
The GLP-1 Receptor Agonist Market Report by The Business Research Company delivers a detailed market assessment, covering size projections from 2025 to 2034. This report explores crucial market trends, major drivers and market segmentation by [key segment categories].
What Is the Current GLP-1 Receptor Agonist Market Size and Its Estimated Growth Rate?
The market for GLP-1 receptor agonist has seen consistent expansion in the past few years. It is projected to increase…
Surging Diabetes Cases Fuel Growth In Glp-1 Receptor Agonist Market: Key Factor …
The GLP-1 Receptor Agonist Market Report by The Business Research Company delivers a detailed market assessment, covering size projections from 2025 to 2034. This report explores crucial market trends, major drivers and market segmentation by [key segment categories].
What Is the Current GLP-1 Receptor Agonist Market Size and Its Estimated Growth Rate?
The market for GLP-1 receptor agonist has seen consistent expansion in the past few years. It is projected to increase…
Glucagon-Like Peptide Agonist Pipeline: 60+ Companies Driving Innovation in Trea …
Leading pharma companies are shaping the future of GLP agonist therapies, revolutionizing treatment possibilities.
DelveInsight's 'Glucagon-Like Peptide (GLP) Agonist - Pipeline Insight, 2024' report provides comprehensive global coverage of pipeline Glucagon-like Peptide Agonist therapies in various stages of clinical development. Major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Glucagon Like Peptide Agonist pipeline domain.
For Glucagon-like Peptide Agonist emerging drugs, the Glucagon Like Peptide…
GLP-1 Receptor Agonist Market Trends, Size & Forecast 2024-2033
The Business Research Company recently released a comprehensive report on the Global GLP-1 Receptor Agonist Market Size and Trends Analysis with Forecast 2024-2033. This latest market research report offers a wealth of valuable insights and data, including global market size, regional shares, and competitor market share. Additionally, it covers current trends, future opportunities, and essential data for success in the industry.
According to The Business Research Company's, The glp-1 receptor agonist…
Global Opioid Receptor Agonist Market Research Report 2023-2029
Opioids are a type of painkiller that works by acting on the neurological system. They're mostly utilized for anaesthetic and pain relief. An agonist is a pharmacological molecule that activates specific brain receptors. When only a small number of receptors are engaged, this agonist elicits a strong physiological/pharmacological response, indicating that the medication has high intrinsic activity. Fentanyl, morphine, dihydromorphinone, meperidine, oxycodone, and oxymorphone are all strong agonist opioids. Opioid…