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Oncology Mice Models Market to Reach US$ 390.3 Mn by 2032, Driven by Research Growth

07-18-2025 11:20 AM CET | Health & Medicine

Press release from: Persistence Market Research

Oncology Mice Models Market

Oncology Mice Models Market

✅The Global Oncology Mice Models Market: Overview and Market Statistics

The global oncology mice models market reached a valuation of US$ 390.3 million in 2022, reflecting the critical role these models play in cancer research and drug development. Projected to grow at a steady compound annual growth rate (CAGR) of approximately 6% through 2032, the market's expansion is driven by increasing investments in oncology research, rising cancer incidence worldwide, and advancements in preclinical testing methodologies. Syngeneic tumor mice models dominate the market, expected to reach US$ 219.3 million by 2032, accounting for over half of the total market value. This segment's prominence is attributed to its ability to mimic tumor-immune system interactions accurately, essential for immuno-oncology research.

North America remains the leading geographical region in this market due to the presence of advanced healthcare infrastructure, substantial R&D funding, and a strong pharmaceutical and biotech industry. The U.S., in particular, drives demand owing to its focus on personalized medicine and immunotherapy, fueling the adoption of sophisticated mouse models. Asia Pacific is emerging as a fast-growing market due to rising cancer prevalence and increasing government initiatives to boost biotechnology research in countries such as China and India.

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✅Key Highlights from the Global Oncology Mice Models Market Report

➤ The market is projected to grow at a CAGR of 6% from 2022 to 2032.
➤ Syngeneic tumor mice models will account for more than 50% of the overall market value.
➤ North America holds the largest market share driven by robust R&D infrastructure.
➤ Increasing demand for immuno-oncology therapies is boosting syngeneic model adoption.
➤ Asia Pacific is the fastest-growing region due to rising cancer cases and biotech investments.
➤ Preclinical efficacy and safety testing remain the primary applications driving market growth.

✅Frequently Asked Question

What are the advantages of syngeneic tumor mice models in oncology research?

Syngeneic tumor mice models are widely preferred in oncology research because they involve transplanting tumor cells from the same genetic background into immunocompetent mice. This compatibility allows researchers to study tumor growth and immune responses in an environment that closely mimics the natural tumor microenvironment. Unlike xenograft models, which require immunodeficient mice and cannot replicate immune system interactions fully, syngeneic models help evaluate immunotherapies and combination treatments more effectively. Their cost-effectiveness and relatively shorter study durations add to their popularity. These advantages make syngeneic models indispensable in developing novel cancer therapies, especially in immuno-oncology, where understanding immune evasion and activation mechanisms is critical.

✅Market Segmentation

The oncology mice models market is primarily segmented by product type, with syngeneic tumor mice models, xenograft mice models, genetically engineered mice models, and patient-derived xenograft (PDX) models forming the key categories. Syngeneic models dominate due to their relevance in immuno-oncology and relatively lower costs. Xenograft models continue to hold significant market share, especially for studying human tumor biology in vivo. Genetically engineered mice, though more complex and expensive, are crucial for exploring specific genetic pathways and cancer mechanisms. PDX models, involving implantation of human tumors directly into mice, are gaining traction for personalized medicine applications.

From an end-user perspective, the market is segmented into pharmaceutical and biotechnology companies, academic and research institutes, and contract research organizations (CROs). Pharmaceutical and biotech companies lead demand due to their extensive drug discovery pipelines. Academic and research institutions drive innovation by developing novel models and exploring cancer biology. CROs contribute by offering outsourced preclinical testing services, thus expanding market reach and facilitating cost-effective research.

✅Regional Insights

North America, led by the United States, dominates the global oncology mice models market, thanks to advanced research facilities, significant public and private funding, and a large pipeline of oncology drugs requiring preclinical testing. Europe follows closely, with strong biotechnology hubs in Germany, the UK, and France pushing innovations in mouse model development.

Asia Pacific is rapidly expanding its share, fueled by increasing cancer incidence, growing awareness, and government support in countries like China, Japan, and India. This region benefits from a large patient population and rising clinical research activities, making it an attractive market for oncology research models.

✅Market Drivers

The primary driver of growth in the oncology mice models market is the increasing global burden of cancer, which fuels demand for more effective therapies. Rising investments in oncology R&D, particularly in immuno-oncology, create a pressing need for reliable preclinical models to test novel treatments. Additionally, technological advancements in genetic engineering and model customization enhance the applicability of mice models, driving market expansion.

✅Market Restraints

Despite the growth potential, the oncology mice models market faces challenges such as ethical concerns related to animal testing, regulatory hurdles, and the high costs associated with maintaining and breeding specialized mouse strains. Additionally, translational gaps-where results in mouse models do not always replicate human clinical outcomes-limit market growth and necessitate complementary testing methods.

✅Market Opportunities

Opportunities lie in the integration of cutting-edge technologies such as CRISPR/Cas9 gene editing to create more precise and human-relevant mouse models. The rising adoption of patient-derived xenograft models and humanized mice presents further avenues for personalized cancer research. Expanding markets in Asia Pacific and increased collaborations between pharmaceutical companies and academic institutions also offer significant growth prospects.

✅Reasons to Buy the Report

1. ✔ Comprehensive analysis of global oncology mice models market trends and forecasts.
2. ✔ Detailed segmentation by product type and end-user for targeted insights.
3. ✔ In-depth regional market analysis including emerging markets.
4. ✔ Identification of key market drivers, restraints, and growth opportunities.
5. ✔ Profiles of leading players and recent developments shaping the industry.

✅Company Insights

✦ Charles River Laboratories International, Inc.
✦ The Jackson Laboratory
✦ Taconic Biosciences
✦ Envigo RMS, LLC
✦ CrownBio
✦ Biomodels, Inc.

■ Charles River Laboratories expanded its oncology research portfolio by acquiring a specialized mouse model developer in 2023.

■ The Jackson Laboratory launched a new genetically engineered mouse model platform tailored for immuno-oncology in early 2024.

✅Conclusion

The global oncology mice models market is poised for sustained growth over the coming decade, driven by rising cancer prevalence and the expanding scope of immuno-oncology research. Syngeneic tumor mice models continue to lead the market due to their relevance in studying immune interactions, while innovations in genetic engineering and model customization offer promising opportunities. Despite challenges such as ethical concerns and translational limitations, expanding research infrastructure in North America and emerging markets in Asia Pacific ensure the market remains vibrant. Companies investing in advanced mouse models and forging collaborations are well-positioned to capitalize on the increasing demand for preclinical cancer research tools.

✅About Persistence Market Research:

At Persistence Market Research, we specialize in creating research studies that serve as strategic tools for driving business growth. Established as a proprietary firm in 2012, we have evolved into a registered company in England and Wales in 2023 under the name Persistence Research & Consultancy Services Ltd. With a solid foundation, we have completed over 3600 custom and syndicate market research projects, and delivered more than 2700 projects for other leading market research companies' clients.

Our approach combines traditional market research methods with modern tools to offer comprehensive research solutions. With a decade of experience, we pride ourselves on deriving actionable insights from data to help businesses stay ahead of the competition. Our client base spans multinational corporations, leading consulting firms, investment funds, and government departments. A significant portion of our sales comes from repeat clients, a testament to the value and trust we've built over the years.

Contact Us:

Persistence Market Research
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Brentford, London, TW8 0GU UK
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Email: sales@persistencemarketresearch.com
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