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Oxycodone Hydrochloride Market to Reach US$ 675.2 Mn by 2034 amid Rising Surgical Volume and Chronic Disease Burden: Transparency Market Research

Oxycodone Hydrochloride Market to Reach US$ 675.2 Mn by 2034 amid

The global oxycodone hydrochloride market stood at US$ 403.9 Mn in 2023. The market is anticipated to grow at a CAGR of 4.8% from 2024 to 2034 and reach US$ 675.2 Mn by the end of 2034, according to the latest research report by Transparency Market Research.

Rising number of surgical interventions globally, increasing need for pain management in chronic ailments, and greater awareness of opioid therapeutics are key factors driving demand for oxycodone hydrochloride. Its role in treating moderate to severe pain, especially when non-opioid treatments are ineffective, continues to gain clinical relevance.

Market participants are focusing on improving access to pain management in emerging markets and expanding product portfolios with advanced formulations to address regulatory and therapeutic needs.

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Market Drivers

Surge in Surgeries and Post-operative Pain Management Fueling Demand

Increasing surgical volumes across orthopedic, oncology, and general surgery fields are prompting the widespread use of oxycodone hydrochloride for immediate and long-term pain management. With over 313 million surgeries performed annually, there is a growing emphasis on optimized post-operative care using pharmaceutical-grade analgesics.

Hospitals and ambulatory surgical centers are actively integrating opioid pain control into recovery protocols. Clinical trials-such as the 2022 study by the Third People's Hospital of Chengdu-have evaluated oxycodone's effectiveness in bariatric surgery recovery, further validating its therapeutic use.

Growing Adoption for Chronic Pain and Cancer Therapy

Oxycodone hydrochloride is increasingly used to treat persistent pain associated with chronic illnesses, including cancer, osteoarthritis, and postherpetic neuralgia. Its minimal immunosuppressive effect and compatibility with long-term treatment regimens make it a preferred analgesic.

As per data from the Cancer Journal and NCBI, over 50% of patients with advanced cancer are prescribed oxycodone HCl as a short-acting agent. Furthermore, its safety and efficacy in pediatric orthopedic pain management add to its clinical appeal.

Regional Market Outlook

North America Dominates Global Landscape

North America held a dominant share of over 40% in the global market in 2023. High prevalence of chronic diseases, aging demographics, and well-established healthcare infrastructure contribute to this leadership.

According to the American Cancer Society, 1.9 million new cancer cases were reported in the U.S. in 2022.

In Canada, 15% of the population aged 20+ suffers from osteoarthritis (ACREU, 2021).

Regulatory approvals and launch of new formulations in the U.S. are reinforcing market growth. In July 2022, Protega Pharmaceuticals introduced RoxyBond (immediate-release oxycodone), supporting safer opioid use.

Competitive Landscape

Leading players in the oxycodone hydrochloride industry are focused on product innovation, strategic partnerships, and expanding distribution networks across untapped regions. Emphasis is placed on extended-release and abuse-deterrent formulations.

Prominent Manufacturers Include:

Eli Lilly and Company
Gilead Sciences, Inc.
Manus Aktteva Biopharma LLP
Teva Pharmaceutical Industries Ltd.
Sun Pharmaceutical Industries Limited
Cipla Ltd.
Dr. Reddy's Laboratories
Sanofi S.A.
Johnson & Johnson
Mallinckrodt Pharmaceuticals

Key Developments in the Oxycodone Hydrochloride Market

August 2022 - General Hospital of Ningxia Medical University conducted a clinical trial on oxycodone HCl to manage bladder discomfort post-transurethral resection of bladder tumors.
July 2022 - Kowa Pharmaceuticals launched SEGLENTIS, an opioid agonist with anti-inflammatory effects for acute pain therapy.

Oxycodone Hydrochloride Market: Segmentation

By Type

Controlled-Release
Immediate-Release

By Route of Administration

Oral
Parenteral

By Distribution Channel

Hospital Pharmacies
Retail Pharmacies
Online Pharmacies

Regions Covered

North America (U.S., Canada)
Europe (Germany, U.K., France, Italy, Spain)
Asia Pacific (China, India, Japan, Australia & New Zealand)
Latin America (Brazil, Mexico)
Middle East & Africa (South Africa, GCC)

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About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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