Press release
Atypical Hemolytic Uremic Syndrome Treatment Market Set to Reach New Heights with Pipeline Innovations and FDA Approvals
"The Global Atypical Hemolytic Uremic Syndrome Treatment Market reached US$1.43 billion in 2025 and is expected to reach US$2.31 billion by 2035, growing at a CAGR of 4.9% during the forecast period 2025-2035," according to DataM Intelligence.The Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market is highly competitive and innovation-driven, with leading companies like Alexion Pharmaceuticals, Inc. (AstraZeneca), Novartis AG, GNHIndia, Omeros Corporation, Chugai Pharmaceutical Co., Ltd., and Bio-Rad Laboratories, Inc. holding significant market share. These players are investing in next-generation complement inhibitors, expanding clinical trials, and engaging in partnerships with rare disease-focused biotech firms to enhance global reach.
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Mergers & Acquisitions in the Atypical Hemolytic Uremic Syndrome Treatment Market
1. AstraZeneca (Alexion) entered a strategic licensing agreement with a European biotech firm for a novel factor B inhibitor aimed at treating rare complement-mediated diseases, including aHUS.
2. Novartis AG announced the acquisition of a gene therapy platform startup focusing on renal indications, with potential applications in atypical HUS.
3. Omeros Corporation partnered with a Japanese pharma company to co-develop and commercialize narsoplimab, its MASP-2 inhibitor, across APAC regions.
As per our analysis, these developments reflect intensified efforts in pipeline diversification and regional market access.
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Key Growth Drivers & Emerging Opportunities in the aHUS Treatment Market
1. Rising incidence of atypical HUS and improved rare disease surveillance globally.
2. Strong pipeline of complement pathway inhibitors (e.g., factor D, C5, MASP-2).
3. Favorable regulatory pathways, including orphan drug and breakthrough therapy designations.
4. Increasing adoption of biosimilars and long-acting biologics (Ravulizumab).
5. Strategic collaborations among biotech and big pharma to address treatment gaps.
6. Expanding pediatric trial enrollment and real-world evidence generation for treatment efficacy.
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Regional Market Drivers Fueling Growth in Atypical Hemolytic Uremic Syndrome (aHUS) Treatment
North America dominates the market with robust healthcare infrastructure, widespread use of Eculizumab/Ravulizumab, and high awareness.
Europe: Government support for orphan drugs and expanding access programs for rare renal disorders.
Asia-Pacific: Emerging as a key region due to rising diagnostics in nephrology and collaborations with local biotech firms for affordable access.
Latin America & MEA: Growth spurred by NGO initiatives and international funding for rare disease treatments.
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