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Major Growth Driver Identified in 2025 Alpha Mannosidosis Market: Harnessing Precision Medicine Fueling Growth In The Alpha-Mannosidosis Market Through Tailored Treatments

07-17-2025 12:47 PM CET | Health & Medicine

Press release from: The Business Research Company

Alpha Mannosidosis Market Size

Alpha Mannosidosis Market Size

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Alpha Mannosidosis Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
In present times, the market size of alpha mannosidosis has seen a quick expansion. From being valued at $15.1 billion in 2024, it is expected to rise to $18.02 billion in 2025, with a compound annual growth rate (CAGR) of 19.3%. The remarkable growth in the past years can be linked to the emerging market expansion, urbanization, a higher demand for artificial fibres, along with government-driven initiatives geared towards the textile industry.

Alpha Mannosidosis Market Size Forecast: What's the Projected Valuation by 2029?
The alpha mannosidosis market is anticipated to experience a significant surge over the foroming years, escalating to a worth of $34.52 billion by 2029 with a compound annual growth rate (CAGR) of 17.6%. Factors contributing to this projected growth include rising global populace and urbanization, the surge in e-commerce, greater demand for sportswear, the expansion of structured retail in emergent economies, and increased use of social media. The forecast period also highlights the growing trend towards using enzyme therapy, embracing the practice of hematopoietic stem cell transplantation, and utilizing cisterna magna infusion.

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What Are the Drivers Transforming the Alpha Mannosidosis Market?
The alpha mannosidosis market growth is anticipated to be driven by the increasing necessity for precision medicine. This specialized approach to healare takes into account the unique genetic, environmental, and lifestyle factors of each patient, helping fine-tune treatments and preventative measures. Accelerated by the evolution of genomic technologies and data analytics, precision medicine lets healare providers identify genetic variations and their health impact with greater accuracy. The mounting demand for custom treatment alternatives, along with a growing recognition of the shortcomings of generic methods, has spurred interest in custom-made healare options. Precision medicine bolsters the creation of therapies that are tailored specifically to the gene mutations and patient profiles related to this uncommon disorder. For example, the Personalized Medicine Coalition (PMC), a non-profit umbrella organization based in the U.S., disclosed that in 2023, the FDA sanctioned 16 new custom treatments for rare diseases as per data from February 2024. This was a remarkable increase from only six approvals in 2022. Consequently, the alpha mannosidosis market is experiencing growth spurred by the escalating need for precision medicine.

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What Long-Term Trends Will Define the Future of the Alpha Mannosidosis Market?
Top firms in the alpha mannosidosis market are concentrating their efforts on the creation of enzyme replacement therapies for the rare alpha-mannosidosis disorder. This therapy involves the introduction of exogenous alpha-mannosidase which aids in the reduction of mannose-rich oligosaccharides pile-up in different tissues and organs. This build-up is a distinct characteristic of alpha-mannosidosis and plays a significant role in its pathological consequences. In February 2023, for example, Chiesi Global Rare Diseases, a US-based pharmaceutical corporation, introduced Lamzede (velmanase alfa). It is the first enzyme replacement therapy to be approved in the US for alpha-mannosidosis treatment, a rare genetic disorder identified by the absence of the alpha-mannosidase enzyme in the body, affecting areas outside the central nervous system. Lamzede mimics the action of the body's alpha-mannosidase enzyme, restoring typical cellular functions in patients. Patients are given an injection of 10 mg of Lamzede once a week.

Which Segments in the Alpha Mannosidosis Market Offer the Most Profit Potential?
The alpha mannosidosis market covered in this report is segmented -

1) By Therapy Type: Bone Marrow Transplant (BMT), Enzyme Replacement Therapy (ERT), Other Therapies
2) By Indication: Type I, Type II, Type III
3) By End-User: Hospitals, Speciality Clinics

Subsegments:
1) By Bone Marrow Transplant (BMT): Autologous BMT, Allogeneic BMT
2) By Enzyme Replacement Therapy (ERT): Recombinant Enzymes, Long-acting Enzyme Formulations
3) By Other Therapies: Symptomatic Treatments, Gene Therapy, Supportive Care

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Which Firms Dominate the Alpha Mannosidosis Market by Market Share and Revenue in 2025?
Major companies operating in the alpha mannosidosis market include Chiesi Farmaceutici S.p.A., Cipla, Daiichi Sankyo Company, Ultragenyx Pharmaceutical Inc, Mitsubishi Tanabe Pharma, Merck, Bristol-Myers Squibb, Novartis AG, Amgen, Centogene, Zymenex A/S, Albumedix Ltd, Kite Pharma, Catalent, Freeline Therapeutics, Avectas, DiNAQOR AG, Vivet Therapeutics, Allergan, PsiOxus Therapeutics, Herantis Pharma Plc, Biocad, Celgene Corporation, Johnson & Johnson, F. Hoffmann-La Roche Ltd, Eli Lilly and Company, Bayer AG, PTC Therapeutics, Gilead Sciences Inc., GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Pfizer S.R.L., AstraZeneca plc, Biogen SA, Sanofi, Adcock Ingram

Which Regions Offer the Highest Growth Potential in the Alpha Mannosidosis Market?
North America was the largest region in the alpha mannosidosis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the alpha mannosidosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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