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2025 Vascular Endothelial Growth Factor (VEGF) Inhibitor Industry Trends Report: Long-Term Outlook Through 2034

07-17-2025 07:29 AM CET | Health & Medicine

Press release from: The Business Research Company

Vascular Endothelial Growth Factor (VEGF) Inhibitor Market

Vascular Endothelial Growth Factor (VEGF) Inhibitor Market

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Vascular Endothelial Growth Factor (VEGF) Inhibitor Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
In recent times, there has been notable growth in the market size of the vascular endothelial growth factor (VEGF) inhibitor. The market, which will be valued at $43.44 billion in 2024, is projected to escalate to $46.64 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 7.4%. Factors propelling this growth during the historical period include a rise in the occurrence of cancer, robust economic expansion in emerging markets, an upswing in pharmaceutical R&D expenditure, increased spending on healthcare, governmental initiatives, and a swift surge in the senior citizen population.

Vascular Endothelial Growth Factor (VEGF) Inhibitor Market Size Forecast: What's the Projected Valuation by 2029?
The market for inhibitors of the vascular endothelial growth factor (VEGF) is set to experience robust growth in the coming years. By 2029, it's predicted that it will have expanded to $59.48 billion, exhibiting a compound annual growth rate (CAGR) of 6.3%. The expected growth is attributed to several factors, including a higher prevalence of cancer, an increase in age-related macular degeneration (AMD), a surge in healthcare spending, the untapped potential of emerging markets, wider usage of biosimilar drugs, and a rise in the aging population. Significant trends shaping this growth are: the idea of providing combination treatments to battle advanced cancers and better the life quality of patients; strategic collaboration efforts to enhance innovations and establish command over market categories; extensive investment in research and development activities to pioneer innovative and effective therapies; increased production of biosimilar medicines to make treatment more affordable for a larger market segment; and a concerted effort to lessen dosages for patients with wet age-related macular degeneration (AMD) for better patient care and welfare.

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What Are the Drivers Transforming the Vascular Endothelial Growth Factor (VEGF) Inhibitor Market?
The escalating incidence of cancer and macular degeneration diseases is anticipated to spur the growth of the VEGF inhibitor market. For example, a report from the US-based American Cancer Society made public in January 2023 predicted roughly 59,610 new cases of all kinds of leukemia and around 23,710 leukemia-related deaths in the United States for that year. Additionally, the same report estimated about 20,380 new occurrences of acute myeloid leukemia (AML) and nearly 11,310 AML-linked fatalities within the same timeframe. Therefore, the increasing prevalence of cancer coupled with macular degeneration disease fuels the expansion of the vascular endothelial growth factor (VEGF) inhibitor market throughout the projected period.

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What Long-Term Trends Will Define the Future of the Vascular Endothelial Growth Factor (VEGF) Inhibitor Market?
Major players in the VEGF inhibitor sector are creating numerous alliances and joint ventures to enlarge their range of products through the invention of new items. This expansion of the product portfolio is a tactic businesses implement to facilitate their growth and amplify their market presence by fulfilling customer needs. The procedure for product development encompasses ideation, designing, creation, and promotion of brand new or newly rebranded products or services. To illustrate, in April 2024, a pharmaceutical company from Japan, Santen Pharmaceutical Co. Ltd., teamed up with Bayer Yakuhin, a life sciences and pharmaceutical firm in Japan, to introduce the Ophthalmic VEGF Inhibitor Eylea 8mg Solution for Intravitreal Injection 114.3 mg/mL. This is commonly used for treating conditions like diabetic macular edema (DME) and age-related macular degeneration (nAMD), which may result in blindness. With a higher concentration than the previous version, Eylea 8mg offers a longer dosing interval of up to 16 weeks, which lowers the number of intravitreal injections while assuring effectiveness and safety. This development seeks to reduce the treatment load on patients and establish a new care standard. It is a tactical partnership committed to extending the scope and accessibility of this pioneering ophthalmic treatment.

Which Segments in the Vascular Endothelial Growth Factor (VEGF) Inhibitor Market Offer the Most Profit Potential?
The vascular endothelial growth factor (VEGF) inhibitor market covered in this report is segmented -

1) By Drugs Type: Avastin, Tecentriq, Lucentis, Tagrisso, Cometriq, Eylea, Other Drug Types
2) By Route Of Administration: Oral, Intravenous, Intravitreal
3) By Application: Oncology, Ophthalmology, Other Applications

Subsegments:
1) By Avastin: Oncology Applications, Ophthalmology Applications
2) By Tecentriq: Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Bladder Cancer, Triple-Negative Breast Cancer
3) By Lucentis: Wet Age-Related Macular Degeneration (AMD), Diabetic Retinopathy, Retinal Vein Occlusion
4) By Tagrisso: First-Line Treatment, Second-Line Treatment
5) By Cometriq: Medullary Thyroid Cancer, Renal Cell Carcinoma
6) By Eylea: Wet Age-Related Macular Degeneration (AMD), Diabetic Macular Edema (DME), Retinal Vein Occlusion (RVO)
7) By Other Drug Types: Immuno-Oncology Drugs, Anti-Angiogenic Agents, Other Monoclonal Antibodies

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Which Firms Dominate the Vascular Endothelial Growth Factor (VEGF) Inhibitor Market by Market Share and Revenue in 2025?
Major companies operating in the vascular endothelial growth factor (VEGF) inhibitor market include F. Hoffmann-La Roche AG, Bayer AG, Regeneron Pharmaceuticals Inc., AstraZeneca Plc., Novartis AG, Pfizer Inc., Eli Lilly and Company, Exelixis Inc., Amgen Inc., Sanofi S.A., Cipla Limited, Biocon, Dr. Reddy's Laboratories, Chi-Med, Innovent Biologics, Daiichi Sankyo, Chugai Pharmaceutical Co. Ltd, Boehringer Ingelheim International GmbH, GlaxoSmithKline plc, Ipsen, Oxurion, Pharmstandard Group, Zentiva, Coherus BioSciences Inc., AVEO pharmaceuticals, Eisai Co. Ltd.

Which Regions Offer the Highest Growth Potential in the Vascular Endothelial Growth Factor (VEGF) Inhibitor Market?
North America was the largest region in the vascular endothelial growth factor (VEGF) inhibitor market in 2024. Middle East is expected to be the fastest-growing region in the vascular endothelial growth factor (VEGF) inhibitor market share during the forecast period. The regions covered in the vascular endothelial growth factor (VEGF) inhibitor market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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