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Surge Of Product Developments In Downstream Processing Market Industry Trends Gaining Momentum in the Global Downstream Processing Market

07-16-2025 04:01 PM CET | Health & Medicine

Press release from: The Business Research Company

Downstream Processing

Downstream Processing

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Downstream Processing Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
The market size of downstream processing has seen significant growth lately. The projections indicate that its value will rise from $31.26 billion in 2024 to $35.54 billion in 2025, representing a compound annual growth rate (CAGR) of 13.7%. Factors contributing to this historical growth include increased biopharmaceutical investments, stricter regulatory standards, the global expansion of biopharmaceutical production, and an increase in chronic disease incidents.

Downstream Processing Market Size Forecast: What's the Projected Valuation by 2029?
In the coming years, the size of the downstream processing market is set to experience a rapid expansion. It is predicted to reach a value of "$58.96 billion in 2029, representing a compound annual growth rate (CAGR) of 13.5%. The accelerated growth during the forecast period can be linked to the rising demand for biopharmaceuticals, emphasis on sustainable and green processing, an increase in collaborations and partnerships, and the acceptance of continuous bioprocessing. Additionally, the growing need for personalized medicines is a significant factor. The forecast period will see trends such as industry 4.0 integration and digitalization, technological breakthroughs, single-use systems, the development of the biopharmaceutical industry, and continuous processing.

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What Are the Drivers Transforming the Downstream Processing Market?
The downstream processing market is projected to see significant growth due to rising healthcare expenses. These expenses include the cost of health services, family planning initiatives, nutrition programs, and health-designated emergency aid. As healthcare spending increases, so too does the demand for downstream processing, which is instrumental in isolating a drug substance (DS) from natural sources such as bacterial or animal cells, and then purifying it. In March 2022, the 2021-2030 National Health Expenditure (NHE) report released by the US-based Centers for Medicare & Medicaid Services predicted that national health spending would experience an average 5.1% annual increase between 2021 and 2030, amounting to approximately $6.8 trillion by 2030. The report also indicated that Medicare outlays would likely grow at a 7.2% annual rate and Medicaid spending at a 5.6% rate during the same period. This escalating healthcare expenditure is thus propelling the growth of the downstream processing market.

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What Long-Term Trends Will Define the Future of the Downstream Processing Market?
Innovations in product development are emerging as significant trends in the downstream processing landscape. Companies leading in this market are strategically focusing on creating novel technological solutions to consolidate their market standing. To illustrate, Tosoh Bioscience LLC, a globally renowned chemical and specialty materials company based in the US, unveiled the Octave BIO Multi-Column Chromatography (MCC) system in September 2022. This comprehensive multi-column chromatography solution was engineered specifically for downstream process intensification. This state-of-the-art MCC system is tailored specifically for biomolecule purification process intensification and also for process development and proof of concept. Its distinct modular design is capable of adapting to a broad spectrum of requirements. Moreover, it also facilitates the opportunity to realize MCC's resin and buffer cost savings and additional tangible benefits.

Which Segments in the Downstream Processing Market Offer the Most Profit Potential?
The downstream processing market covered in this report is segmented -

1) By Product: Centrifuges, Dryers, Chromatography Systems, Filters, Evaporators, Other Products
2) By Technique: Purification Techniques, Solid-Liquid Separation, Clarification Or Concentration
3) By Application: Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production, Other Applications

Subsegments:
1) By Centrifuges: Analytical Centrifuges, Preparative Centrifuges
2) By Dryers: Spray Dryers, Freeze Dryers, Fluidized Bed Dryers
3) By Chromatography Systems: Liquid Chromatography Systems, Gas Chromatography Systems, Affinity Chromatography Systems
4) By Filters: Membrane Filters, Depth Filters, Cartridge Filters
5) By Evaporators: Thin Film Evaporators, Forced Circulation Evaporators, Falling Film Evaporators
6) By Other Products: Mixers, Precipitation Systems, Storage Tanks

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Which Firms Dominate the Downstream Processing Market by Market Share and Revenue in 2025?
Major companies operating in the downstream processing market include Sartorius AG, General Electric Company, Merck KGaA, Thermo Fisher Scientific Inc., Danaher Corporation, Repligen Corporation, Lonza Group Ltd., Eppendorf AG, Corning Corporation, Ashai Kasei Corporation, Finesse Solutions Inc., MilliporeSigma, Pall Corporation, Bio-Rad Laboratories, Charles River Laboratories International Inc., Waters Corporation, Becton Dickinson and Company (BD), Entegris Inc., Novasep, Avantor Sciences, Tecan Group, Agilent Technologies, Boehringer Ingelheim International GmbH, Ahlstrom-Munksjö Oyj, Grifols S.A., GenScript Biotech Corporation

Which Regions Offer the Highest Growth Potential in the Downstream Processing Market?
North America was the largest region in the downstream processing market in 2024.Asia-Pacific is expected to be the fastest-growing region in the global downstream processing market report during the forecast period. The regions covered in the downstream processing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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Our flagship product, the Global Market Model (GMM), is a premier market intelligence platform delivering comprehensive and updated forecasts to support informed decision-making.

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Learn More About The Business Research Company
With over 15,000+ reports from 27 industries covering 60+ geographies, The Business Research Company has built a reputation for offering comprehensive, data-rich research and insights. Our flagship product, the Global Market Model delivers comprehensive and updated forecasts to support informed decision-making.

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