Monkeypox Market to Reach USD 264 Million by 2031 Amid Global Vaccine and Diagnostic Expansion

"Global Monkeypox Market reached US$93.17 million in 2023 and is expected to reach US$264 million by 2031, growing at a CAGR of 10.16% during the forecast period 2024-2031", according to DataM Intelligence research.

The Monkeypox market is growing steadily due to increased global surveillance and early diagnostic adoption, as per our analysis. Governments are investing in vaccine stockpiling, especially JYNNEOS, to strengthen outbreak preparedness.
Emerging markets are expanding access through partnerships with the WHO, Gavi, and the Africa CDC. Ongoing research into next-gen vaccines and antivirals is creating new commercial opportunities.

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Strategic Partnerships and Global M&A Developments Reshaping the Monkeypox Market Landscape

• Bavarian Nordic secures major U.S. vaccine order: In May 2025, Bavarian Nordic received a USD 63 million federal contract to supply bulk JYNNEOS vaccine doses, reflecting the U.S. government's growing investment in domestic monkeypox preparedness and public health stockpiling.

• Gavi-Africa CDC vaccine procurement partnership: In June 2025, Gavi and Africa CDC jointly facilitated the purchase of 5,000 monkeypox vaccine doses, strengthening outbreak response capacity across African regions.

• Tonix Pharmaceuticals partners on novel poxvirus vaccine research: In July 2025, Tonix initiated a collaboration with Kenya Medical Research Institute to advance its TNX-801 vaccine candidate for monkeypox and smallpox through preclinical and Phase I development.

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Competitive Landscape: Key Companies Shaping the Global Monkeypox Market

The global Monkeypox market features a mix of multinational pharmaceutical giants and specialized biotech firms working to expand access to vaccines, antivirals, and diagnostics.

Leading the space is Bavarian Nordic A/S, known for its JYNNEOS vaccine, alongside Emergent BioSolutions Inc. and SIGA Technologies, Inc., both active in biodefense and outbreak preparedness.

Companies like Pfizer Inc., Teva Pharmaceuticals USA, Inc., and Sun Pharmaceutical Industries Ltd. are leveraging their global distribution networks to support public health responses.

Meanwhile, regional players such as Wellona Pharma, Zuche Pharmaceuticals, and Sambria Pharmaceuticals are contributing to market growth through affordable generics and localized supply.

With ongoing innovation and global partnerships, these companies are driving the evolution of Monkeypox prevention and treatment worldwide.

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Regional Market Trends Highlight Evolving Monkeypox Response Across Global Health Systems

• North America retains its leading position, supported by consistent vaccine demand, federal purchasing programs, and widespread diagnostic infrastructure upgrades.
• Europe continues to show moderate growth, focusing on regional stockpile coordination and improved cross-border disease surveillance frameworks.
• In Asia-Pacific, the market is evolving with regulatory progress, pilot immunization rollouts, and increased public sector interest in domestic production.
• Latin America, the Middle East, and Africa are seeing gradual expansion, led by donor-backed health programs, improved disease monitoring, and region-specific vaccine access models.

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