Cell and Gene Therapy Market Attracts Biotech Giants, Growing at 21.5% CAGR During 2025-2033 Forecast | Top Companies 2025 - Novartis AG, Gilead Sciences, Inc., Bristol Myers Squibb Company

Cell and Gene Therapy Market size reached US$ 13.90 Billion in 2024 and is expected to reach US$ 105.83 Billion by 2033, growing at a CAGR of 21.5% during the forecast period 2025-2033.

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Cell and Gene Therapy Market Landscape Analysis :

Cell and gene therapy refers to advanced biomedical treatments that modify or replace faulty genes or introduce new cells to treat or cure diseases at the molecular level. These therapies offer transformative potential for conditions previously considered incurable, including rare genetic disorders, cancer, and certain autoimmune diseases.

Cell and Gene Therapy Market Dynamics:

The growing use of advanced delivery vectors is boosting the cell and gene therapy market. These vectors improve the efficiency and safety of genetic material delivery, enhancing treatment outcomes. New platforms like AGC Biologics' BravoAAV and ProntoLVV (2023) support faster, scalable production. Charles River's 2024 launch of GMP-grade AAV and LVV materials further supports CGT development. These innovations help reduce immune responses and increase clinical success rates.

Cell and Gene Therapy Market: Recent Industry Developments

✅In May 2025 The first in vivo customized CRISPR treatment was administered to a baby with a rare liver metabolic disorder, using Acuitas-made lipid nanoparticles to deliver the gene-editing payload, marking a major milestone in personalized gene therapy

✅In April 2025 Prademagene zamikeracel (Zevaskyn), an autologous skin cell gene therapy, was approved in the U.S. for recessive dystrophic epidermolysis bullosa, addressing chronic wounds

Strategic Players Driving the Cell and Gene Therapy Market Forward:

Novartis AG, Gilead Sciences, Inc., Bristol Myers Squibb Company, Vertex Pharmaceuticals Incorporated, Sarepta Therapeutics, Inc., CSL Behring LLC, Amgen, Inc., Orchard Therapeutics group, Krystal Biotech, Inc., bluebird bio, Inc., and among others. Emerging market players include Editas Medicine, Intellia Therapeutics, Rocket Pharmaceuticals, Regenxbio, Affinia Therapeutics, and others.

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Research Methodology:
The global Cell and Gene Therapy Market research report employs a comprehensive dual-source approach, integrating both primary and secondary data collection methods to ensure robust market analysis. Our research framework systematically evaluates multiple industry-influencing variables, including regulatory frameworks and government policies, prevailing market conditions, competitive intensity levels, historical performance data, current market positioning, technological innovations and disruptions, emerging industry developments, cross-sector business impacts, market volatility patterns, growth prospects, potential market barriers, and strategic challenges facing industry participants.

Segment Covered in the Cell and Gene Therapy Market:

➥By Therapy Type: Cell Therapy, Gene Therapy

➥By Application: Oncology, Musculoskeletal Conditions, Ophthalmology, Blood Disorders, Immunodeficiency Disorders, Graft-versus-host disease (GVHD), Rare Diseases, Others

Regional Analysis for Cell and Gene Therapy Market:
⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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Most Frequently Asked Questions in the Cell and Gene Therapy Market Research Industry:
➠ Who leads the Cell and Gene Therapy industry and what's their competitive positioning regarding capacity, performance, and profitability?
➠ What growth opportunities and market challenges do Cell and Gene Therapy market vendors face?
➠ Which segments show the highest growth potential and market share distribution?
➠ What factors are driving or limiting Cell and Gene Therapy market growth?
➠ What are the dominant sales and distribution strategies in the Cell and Gene Therapy industry?

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