U.S. Ambulatory Infusion Centers Market Forecast 2035: Shift Toward Outpatient Care and Chronic Disease Management Fuels Market Growth | Transparency Market Research, Inc

The U.S. ambulatory infusion centers market was valued at US$ 8.9 billion in 2024 and is projected to expand at an impressive CAGR of 8.8% from 2025 to 2035, reaching approximately US$ 22.5 billion by the end of 2035. This growth reflects a strong shift in U.S. healthcare towards outpatient care models that balance affordability, convenience, and high-quality service.

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With rising chronic disease prevalence, a broader portfolio of infusion therapies, and evolving reimbursement models supporting site-of-care optimization, ambulatory infusion centers (AICs) are increasingly recognized as essential to modern, patient-centered healthcare.

Market Introduction: Changing the Landscape of Infusion Therapy

Ambulatory infusion centers offer outpatient intravenous treatments outside hospital settings, supporting patients who require repeated infusions for chronic illnesses like cancer, autoimmune diseases, and neurological disorders. These centers deliver specialized care in comfortable environments, reducing the need for hospital admissions while improving patient satisfaction.

Several factors are accelerating market growth:

Biologic and specialty drug innovations: As more targeted therapies enter the market, demand for outpatient infusion services increases.

Technological improvements: Smart infusion pumps, integration with EHR systems, and remote monitoring tools enhance safety and efficiency.

Patient preference: AICs reduce treatment burden, enabling patients to maintain daily routines.

The U.S. ambulatory infusion center market reflects this shift from volume-based care to value-based care-offering better outcomes, reduced costs, and higher satisfaction for patients and providers alike.

Market Drivers: Cost Efficiency and Favorable Reimbursement Models

One of the strongest market drivers is the cost-effectiveness of ambulatory infusion centers compared to hospital-based services. Studies have shown that treatments at AICs can lower healthcare costs by up to 30% relative to hospital outpatient departments-saving between US$ 1,000-1,500 per infusion.

Additionally, the Centers for Medicare & Medicaid Services (CMS) and commercial insurers are actively promoting site-neutral payments and bundled payment models to encourage treatment in lower-cost outpatient settings. These policies reduce financial barriers and boost the viability of AICs.

As U.S. healthcare continues its shift to value-based care, where the focus is on quality and efficiency rather than volume, AICs align perfectly with national cost containment and care optimization goals.

Technological Advancements Shaping the Future of AICs

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Technology plays a critical role in strengthening safety, efficiency, and patient experience:

Smart infusion pumps with real-time alerts reduce adverse events by detecting issues like infiltration or air bubbles.

EHR integration streamlines patient monitoring, dosage adjustments, and documentation.

Remote patient monitoring tools and wearable biosensors extend care beyond infusion sessions, improving post-treatment safety.

AI-driven analytics help identify patients at risk for infusion reactions, supporting personalized treatment plans.

These advancements enable centers to handle more complex therapies safely and efficiently, broadening the range of conditions treated-from multiple sclerosis and Crohn's disease to oncology and rare autoimmune disorders.

Leading Segment: Hospital-Based Infusion Centers

In 2024, hospital-based infusion centers held the largest market share among center types. This dominance is rooted in several factors:

Access to specialized staff, comprehensive care infrastructure, and emergency support.

Integrated, multidisciplinary care delivery-especially critical for complex conditions like cancer.

Preferential insurance and reimbursement policies that bundle infusion therapy costs with other hospital services.

Hospitals also have direct partnerships with pharmaceutical companies, ensuring consistent access to the latest biologics and specialty drugs-a competitive advantage over standalone centers.

U.S. Ambulatory Infusion Centers Market by Disease Specialties

AICs are rapidly diversifying to meet patient needs across disease specialties, including:

Oncology

Pulmonology

Neurology

Gastrointestinal

Immunology

Cardiology

Others (e.g., dermatology, orthopedics, rheumatology)

The rising use of biologics and personalized medicine is driving demand in each specialty, particularly for therapies that require regular, precise administration under clinical supervision.

Key Market Developments

Recent strategic expansions illustrate strong investment momentum:

In January 2025, Optum (part of UnitedHealth Group) agreed to acquire FlexCare Infusion, expanding into the outpatient infusion market to complement its ambulatory surgery network.

In April 2024, Hy-Vee, Inc. opened its first infusion clinic in West Des Moines, Iowa, offering services for chronic conditions in a dedicated outpatient setting.

These moves highlight how established healthcare organizations are investing in AICs to diversify care delivery and capture growing outpatient demand.

Competitive Landscape

Leading players profiled in the market report include:

Flexcare Infusion Centers

Thrivewell

Hy-Vee Health

Agile Infusion Services LLC

Infusion Solutions

IVXpress, Inc.

Infusion for Health

Cedars-Sinai

Arnot Health

PharmaScript

Naval Medical Center Portsmouth

Valley Health Systems

Cheyenne Regional Medical Center

Pacific Medical Centers

ChristianaCare

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These organizations focus on expanding service coverage, integrating digital tools, and offering specialty therapies to meet evolving patient and payer needs.

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