Hyperparathyroidism Pipeline 2025: Groundbreaking Clinical Advancements by 3+ Global Leaders - DelveInsight | Featuring Shanghai Hengrui Pharmaceutical Co., Ltd., Shaanxi Micot Technology Limited Company, Crinetics Pharmaceuticals, Inc., Pathalys Pharma

With Hyperparathyroidism reaching epidemic proportions globally and contributing significantly to comorbid conditions such as diabetes, cardiovascular disease, and certain cancers, there is a growing demand for safer, more effective treatment options. According to DelveInsight, the Hyperparathyroidism pipeline comprises 25+ pharmaceutical and biotech companies actively developing 30+ therapeutic candidates targeting Hyperparathyroidism. These therapies span various stages of clinical and non-clinical development, underscoring the intense innovation and commitment to addressing one of the most pressing public health challenges of our time.
DelveInsight's "Hyperparathyroidism Pipeline Insight 2025" report provides a detailed and strategic evaluation of the ongoing R&D landscape. It covers clinical trial progression, emerging therapies, mechanisms of action, competitive positioning, and key company initiatives. The report serves as a crucial resource for stakeholders, including researchers, healthcare investors, and decision-makers, seeking insights into the evolving Hyperparathyroidism Therapeutics Market and the breakthroughs shaping its future trajectory.

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Key Takeaways from the Hyperparathyroidism Pipeline Report

DelveInsight's Hyperparathyroidism pipeline report depicts a robust space with 3+ active players working to develop 3+ pipeline therapies for Hyperparathyroidism treatment.
In April 2025, Parsabiv (etelcalcetide) was formally approved for treating SHPT in adult dialysis patients. This intravenous calcimimetic is administered post-dialysis three times a week and has demonstrated strong efficacy in phase III trials by significantly reducing PTH levels.
Key Hyperparathyroidism companies such as Shanghai Hengrui Pharmaceutical Co., Ltd., Shaanxi Micot Technology Limited Company, Crinetics Pharmaceuticals, Inc., Pathalys Pharma, and others are evaluating new drugs for Hyperparathyroidism to improve the treatment landscape.
Promising Hyperparathyroidism pipeline therapies in various stages of development include SHR6508, MT1013, and others.

Hyperparathyroidism Overview:

Hyperparathyroidism is a condition in which one or more of the parathyroid glands become overactive and produce excessive parathyroid hormone (PTH). These tiny glands, located near the thyroid at the base of the neck, help regulate calcium and phosphate levels in the body. Under normal conditions, PTH maintains balance by prompting bones to release calcium and phosphate, the kidneys to retain calcium and excrete phosphate, and the intestines to absorb calcium via activated vitamin D. In hyperparathyroidism, elevated PTH levels lead to increased calcium in the blood (hypercalcemia), potentially causing bone weakening, kidney stone formation, and calcium deposits in soft tissues and blood vessels.

Primary hyperparathyroidism is frequently discovered during routine blood work, as it may not produce symptoms initially. When symptoms do arise, they often stem from the consequences of high calcium levels or decreased bone calcium. These may include bone fragility (osteoporosis), kidney stones, frequent urination, abdominal pain, fatigue, muscle weakness, depression, and memory difficulties. Other possible signs include nausea, vomiting, poor appetite, constipation, joint pain, confusion, and excessive thirst. In some cases, individuals may remain asymptomatic and receive a diagnosis only after unrelated medical tests.

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Hyperparathyroidism Pipeline Analysis
The Hyperparathyroidism pipeline insights report 2025, provides insights into:
Provides comprehensive insights into key companies developing therapies in the Hyperparathyroidism Market.

Categorizes Hyperparathyroidism therapeutic companies by development stage: early, mid, and late-stage.

Highlights major companies involved in targeted therapy development, including both active and inactive (paused/discontinued) projects.

Reviews emerging Hyperparathyroidism drugs under development based on:

Stage of development

Hyperparathyroidism Route of administration

Target receptor

Monotherapy vs. combination therapy

Hyperparathyroidism Mechanism of action

Molecular type

Offers detailed analysis of:

Company-to-company and company-academia collaborations

Hyperparathyroidism Licensing agreements

Funding and investment activities supporting future Hyperparathyroidism market advancement.

Unlock key insights into emerging Hyperparathyroidism therapies and market strategies here: https://www.delveinsight.com/report-store/hyperparathyroidism-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr

Hyperparathyroidism Emerging Drugs

SHR6508: Shanghai Hengrui Pharmaceutical Co., Ltd.

SHR6508 is an investigational calcimimetic small molecule developed by Shanghai Hengrui Pharmaceutical Co., Ltd. for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease undergoing hemodialysis. Acting as an agonist of the calcium-sensing receptor, SHR6508 helps regulate calcium signaling in parathyroid cells, thereby reducing the overproduction of parathyroid hormone (PTH). Although its exact molecular mechanism is still being explored, the drug offers a novel strategy by directly targeting receptor activity to help restore hormonal balance. SHR6508 is currently in Phase III clinical trials for managing hyperparathyroidism.

MT1013: Shaanxi Micot Technology Limited Company

MT1013 is a novel investigational therapy developed by Shaanxi Micot Technology Limited Company for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease. As an antagonist of the parathyroid hormone receptor type 1 (PTH1R), MT1013 aims to regulate PTH signaling pathways, providing a new strategy for controlling elevated hormone levels. The drug works by disrupting calcium-dependent signaling in parathyroid cells, which may help suppress the excessive secretion of parathyroid hormone often seen in individuals with impaired kidney function. MT1013 is currently in Phase II clinical trials for hyperparathyroidism.

Hyperparathyroidism Pipeline Therapeutic Assessment

Hyperparathyroidism Assessment by Product Type
• Mono
• Combination
• Mono/Combination

Hyperparathyroidism By Stage
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Hyperparathyroidism Assessment by Route of Administration
• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical

Hyperparathyroidism Assessment by Molecule Type
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

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Table of Contents

1. Report Introduction
2. Executive Summary
3. Hyperparathyroidism Current Treatment Patterns
4. Hyperparathyroidism - DelveInsight's Analytical Perspective
5. Therapeutic Assessment
6. Hyperparathyroidism Late-Stage Products (Phase-III)
7. Hyperparathyroidism Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Hyperparathyroidism Discontinued Products
13. Hyperparathyroidism Product Profiles
14. Hyperparathyroidism Key Companies
15. Hyperparathyroidism Key Products
16. Dormant and Discontinued Products
17. Hyperparathyroidism Unmet Needs
18. Hyperparathyroidism Future Perspectives
19. Hyperparathyroidism Analyst Review
20. Appendix
21. Report Methodology

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Contact Info:
Kritika Rehani
Assistant Manager, Marketing & Branding
krehani@delveinsight.com
info@delveinsight.com
+14699457679

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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