Press release
Key Trends Reshaping the Hypoparathyroidism Market: Transcon Platform Enables Long-Acting Prodrugs For Sustained Hormone Release Industry Transformation
Hypoparathyroidism
Hypoparathyroidism Market Size Growth Forecast: What to Expect by 2025?
In recent times, the hypoparathyroidism market has experienced robust growth. The market size, which stands at $0.95 billion in 2024, is projected to expand to $1.03 billion in 2025, with a compound annual growth rate (CAGR) of 8.6%. This historical growth is due to factors such as the growing number of thyroid surgeries, increased awareness about hypoparathyroidism, a surge in post-operative complications, a rise in the demand for calcium and vitamin D supplements, and an enhanced focus on the management of endocrine disorders.
How Will the Hypoparathyroidism Market Size Evolve and Grow by 2029?
The market for hypoparathyroidism is predicted to experience substantial growth in the upcoming years, with expectations of reaching $1.42 billion in 2029, indicating a compound annual growth rate (CAGR) of 8.3%. This projected growth during the forecast period can be traced back to the increasing incorporation of recombinant parathyroid hormone therapies, escalating investment in hypoparathyroidism research, expansion of the healthcare sector, a growing elderly demographic susceptible to endocrine disorders, and rising awareness leading to early diagnosis. The forecast period is also expected to witness advancements in parathyroid hormone therapies, enhanced diagnostic procedures for hypoparathyroidism, emergence of sustained-release calcium supplements, innovations in minimally invasive thyroid surgery, and further advancements in patient monitoring technologies.
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What Drivers Are Propelling the Growth of Hypoparathyroidism Market Forward?
Rising cases of thyroid cancer are anticipated to fuel the expansion of the hypoparathyroidism market in the future. Thyroid cancer involves the abnormal growth of cells in the thyroid gland, often appearing as a lump in the neck. Improved diagnostic imaging technologies have led to increasing instances of thyroid cancer, as these technologies facilitate early and more regular detection of small, symptomless thyroid nodules. Hypoparathyroidism is indirectly prompted by thyroid cancer due to the increased need for thyroid surgeries, which can unintentionally harm the parathyroid glands. This results in calcium imbalance and persistent hormone deficiency, thereby increasing the need for enduring disease management solutions. For example, the American Cancer Society, a not-for-profit organization based in the US, reported in May 2024 that the number of new thyroid cancer cases surged to 44,020 in 2025 from 43,720 in 2023. Consequently, the escalating instances of thyroid cancer are spurring the growth of the hypoparathyroidism market.
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Which Emerging Trends Are Transforming the Hypoparathyroidism Market in 2025?
Leading companies in the hypoparathyroidism market are striving to create more technologically sophisticated products, such as those based on transition technology, to boost treatment effectiveness and better patient outcomes. These transition technology-based products are therapeutics created with TransCon (Transient Conjugation) technology, an exclusive platform aimed at enhancing drug delivery capabilities. For example, in January 2024, Ascendis Pharma A/S, a biopharmaceutical enterprise based in Denmark, introduced YORVIPATH (palopegteriparatide), its second product using TransCon technology, in Germany and Austria to treat adults suffering from chronic hypoparathyroidism. YORVIPATH is a once-a-day prodrug of parathyroid hormone (PTH 1-34) which aims to sustain physiological PTH levels throughout a 24-hour period, targeting the foundational hormone deficiency found in chronic hypoparathyroidism.
What Are the Key Segments in the Hypoparathyroidism Market?
The hypoparathyroidism market covered in this report is segmented -
1) By Treatment: Hormone Replacement Therapy, Adjunctive Therapies
2) By Type: Hormone Replacement Therapy, Calcium And Vitamin D Supplements, Emerging Therapies
3) By Route Of Administration: Oral, Parenteral
4) By Distribution Channel: Hospital Pharmacy, Retail Pharmacy, Online Pharmacy
5) By End User: Hospitals, Specialty Clinics, Homecare Settings
Subsegments:
1) By Hormone Replacement Therapy: Recombinant Parathyroid Hormone, Parathyroid Hormone Analogues, Calcimimetics, Calcium And Vitamin D Supplements
2) By Adjunctive Therapies: Magnesium Supplements, Phosphate Binders, Other Supportive Therapies
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Who Are the Key Players Shaping the Hypoparathyroidism Market's Competitive Landscape?
Major companies operating in the hypoparathyroidism market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck & Co Inc., AbbVie Inc., Sanofi S.A., Novartis AG, GlaxoSmithKline plc , Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Amgen Inc., Teva Pharmaceutical Industries Ltd., Dr. Reddy's Laboratories Ltd., Cipla Limited , Lupin Limited, Torrent Pharmaceuticals Ltd., Eagle Pharmaceuticals Inc., BridgeBio Pharma Inc., Ascendis Pharma A/S, Extend Biosciences Inc., Entera Bio Ltd.
What Geographic Markets Are Powering Growth in the Hypoparathyroidism Market?
North America was the largest region in the hypoparathyroidism market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the hypoparathyroidism market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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Hypoparathyroidism Market to Reach USD 2.06 Billion by 2034
Pune, India - December 2025 - The global Hypoparathyroidism Market, valued at USD 1.21 billion in 2024, is projected to reach USD 2.06 billion by 2034, growing at a 5.5% CAGR (2025-2034), according to Exactitude Consultancy. Increasing incidence of post-thyroidectomy hypoparathyroidism, improved diagnosis of chronic hypocalcemia, and expanding use of recombinant parathyroid hormone (PTH) therapies are key market growth drivers.
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